In this article, you can read the instructions for use of the drug. Depantol. Presented reviews of visitors to the site - the consumers of this medicine, as well as the opinions of medical specialists on the use of Depantol in their practice. A big request to add your feedback on the drug more actively: the medicine helped or did not help to get rid of the disease, what complications and side effects were observed, perhaps not stated by the manufacturer in the annotation. Depantol analogues with available structural analogues. Use for the treatment of cervical erosion, vaginitis and nipple cracks in adults, children, as well as during pregnancy and lactation.
Depantol - a combined preparation that improves trophism and tissue regeneration, with antimicrobial activity for external use.
Dexpanthenol is a vitamin B group, it is metabolized in the body to pantothenic acid, which is an integral part of coenzyme A and is involved in the processes of acetylation, carbohydrate and fat metabolism, in the synthesis of acetylcholine, glucocorticosteroids (GCS), porphyrins. Stimulates skin regeneration, normalizes cellular metabolism, accelerates mitosis and increases the strength of collagen fibers. It has a regenerating, vitamin, metabolic and anti-inflammatory effect.
Chlorhexidine - antimicrobial drug, antiseptic.
It is active against gram-positive and gram-negative bacteria, incl. Staphylococcus spp. (staphylococcus), Enterococcus spp., Pseudomonas aeruginosa, Escherichia coli (E. coli), Streptococcus spp. (streptococcus), as well as yeast-like fungi and dermatophytes.
Remains active in the presence of blood, pus, various secrets and organic matter. Cream Depantol protects the wound surface from infection, inhibits the course of the infection process and accelerates healing.
Depantol does not violate the functional activity of lactobacilli.
Dexpanthenol + Chlorhexidine digluconate (in the form of a 20% solution) + excipients.
Data on the pharmacokinetics of the drug is not provided.
- acute and chronic vaginitis,
- endocervicitis (including those complicated by cervical ectopia),
- true cervical erosion of a specific etiology (as part of complex therapy),
- to improve the regeneration of the mucous membrane of the vagina and cervix after destructive treatment methods (including diathermocoagulation, cryodestruction, laser destruction), in the postoperative and postnatal periods,
- treatment of wounds at the risk of infection (including abrasions, cuts, scratches, cracks, scratches, insect bites, burns, trophic ulcers),
- treatment of postoperative wounds,
- treatment of infected wounds, burns (incl. solar), bedsores, abrasions, cuts, cracks, trophic ulcers, diaper rash,
- treatment of infected dermatoses (including eczema and atopic dermatitis).
- diaper dermatitis, scratches with signs of infection in children,
- cracks and inflammation of the nipples of the mammary glands with signs of infection in nursing mothers.
Forms of release
Cream for external use (sometimes mistakenly called an ointment or gel).
Instructions for use and method of use
Depantol is administered intravaginally. Before use, the suppository should be removed from the contour packaging.
Introduce 1 candle 2 times a day for 7-10 days. If necessary, it is possible to extend the course of treatment up to 20 days.
The cream should be applied with a thin layer to the affected skin 1 or several times a day if indicated.
Nursing mothers are advised to lubricate the infected surface of the nipple with a cream after breastfeeding.
Infants cream is applied to the site of infection after a change of linen or water treatment.
- allergic reactions, itching and burning (passing after drug withdrawal).
- hypersensitivity to the drug.
Use during pregnancy and lactation
Depantol use during pregnancy and lactation is allowed.
Use in children
It is possible to use the cream according to indications.
Do not let the cream in the eyes.
Depantol is incompatible with detergents containing an anionic group (including saponins, sodium lauryl sulfate, sodium carboxymethylcellulose) and soaps, if they are administered intravaginally.
Analogues of the drug Depantol
Structural analogues of the active substance:
Analogs for pharmacological group (means for treating cervical erosion):
- Tykveol oil for oral administration,
- Chlorophyllipta solution in oil 2%.
Candles "Depantol", the instruction of which must be necessarily studied before their use, is very often used in gynecology. This drug is intended for vaginal administration, and therefore has a special shape and composition. You will learn more about the diseases with which this local medicine is used, whether it has contraindications and what its dosage is.
Description of the drug, its composition
According to the instructions for use, candles "Depantol" have a torpedo shape with a funnel-shaped recess, as well as white, grayish or yellowish color (sometimes marbling is present) without the presence of any pronounced odor.
Vaginal suppositories go on sale in two cellular packs of five pieces, which are placed in a cardboard box with detailed instructions.
Candles "Depantol" contain two active components:
- chlorhexidine digluconate.
Also in the composition of the local medication are auxiliary substances in the form of a basis for the preparation of suppositories and macrogol.
What are the candles "Depantol"? The instructions attached to this drug contain the information that such suppositories are a universal remedy, which is very often recommended to women for the prevention and treatment of various gynecological diseases.
Included in the drug active ingredients have a pronounced regenerating and antimicrobial effect. In addition, they are able to relieve inflammation and suppress the activity of pathogenic microflora.
In the process of absorption of active substances in the mucous membranes of the genital tract improves the renewal of their epithelial layer and restores local metabolism.
Action of active ingredients
The instructions of candles "Depantol" (10 pcs.) States that a substance such as chlorhexidine is able to exhibit pronounced therapeutic activity against gram-negative and gram-positive flora, including chlamydia, treponema, ureaplasma, gardrenella, escherychia, dermatophytes, staphylococci, yeast-like fungi, trichomonads.
As for dexapanthenol, thanks to this component, the considered suppositories accelerate the process of updating the epithelial layer of the mucous membrane and increase the strength of collagen fibers. Also mentioned active substance contributes to the speedy healing of wounds and damage to the genital tract.
It should be noted that the candles "Depantol", the instruction of which contains a lot of useful information for patients, does not adversely affect the growth of beneficial flora. The therapeutic effect after using the suppository is maintained even in the presence of blood and pus.
Prescribing local medication
What is the purpose of using candles "Depantol" in gynecology? Instructions for use reports that the main indications for the appointment of such vaginal suppositories are the following diseases:
- inflammation of the mucous membrane of the vagina, occurring in a chronic or acute form,
- polyps of the vagina or cervix (as part of a complex treatment),
- cervical erosion,
- recurrent thrush,
- rehabilitation of the birth canal before the upcoming childbirth.
Other indications for use of the drug
The Depantol Candle Instructions (analogs of the drug should be used only after consulting with a gynecologist!) Informs that such suppositories can be prescribed to women as a preventive medicine before upcoming or postponed gynecological manipulations, including after insertion / removal of the intrauterine device, surgical abortion, transferred operations, before electrocoagulation of the cervix, etc.
Sometimes the considered drug is used as part of complex therapy for some diseases that are sexually transmitted.
Contraindications to the use of suppositories
Before using candles "Depantol" should definitely refer to a gynecologist, and if necessary - pass tests. It is undesirable to use suppositories without consulting a specialist, as they have such contraindications as:
- malignant growth of cells in the cervix or vagina, including accompanied by severe metastasis,
- idiosyncrasy of the active ingredients of the local drug.
Instructions candles "Depantol"
How many days should the medication be used, and in what dosage should it be used? The number and frequency of use of such suppositories is determined by the doctor individually. It should be recalled that "Depantol" is administered intravaginally for the prevention and treatment of gynecological diseases only for women from 18 years of age.
To properly insert the candle into the vagina, you must take a position lying on your back. The suppository should be inserted deep into the vagina. To achieve the best effect after the procedure, it is recommended to stay in the accepted position for another 40 minutes.
For the treatment of gynecological diseases, this drug is prescribed 1 unit 2 times a day (preferably in the morning and evening). Wash hands thoroughly before inserting the suppository and after the procedure.
The duration of the course of therapy with this medication is 7-10 days. If necessary, it can be prolonged by a doctor’s appointment for the same period.
If the expected therapeutic effect is absent, or the patient's condition worsens, you should immediately contact a specialist to clarify the diagnosis and additional examination.
Side Effects, Overdose Cases
According to experts, the drug in the form of vaginal candles "Depantol" is tolerated by women quite well. In the presence of hypersensitivity to the components that make up the drug, in some cases it is possible to develop such side effects of a local nature as:
- discomfort, itching of the vagina,
- burning in the vagina
- foreign body sensation inside the genital tract.
Usually such manifestations are not dangerous and pass independently after 20 minutes. When they occur, the cancellation of therapy is not required.
As for the cases of overdose, these are not described in the instructions. But to prevent the development of side effects, it is highly undesirable to exceed the dose of the drug, as well as independently increase the duration of the allowable course of therapy.
Analogues of candles
What can replace the considered drug? What are his analogues? Instructions for the use of candles "Depantol" does not provide answers to these questions. To find a similar medicine for the treatment of gynecological diseases, you should consult a specialist.
Typically, such a drug is replaced by the following means: "Miramistin", "Hexicon", "Livarol", "Chlorhexidine". The forms of such drugs may differ from those considered, but they all have similar properties and therapeutic effects.
There are quite a lot of messages from women about candles “Depantol”. And this is not surprising, because such a drug is very often used in gynecological practice.
In the majority of reviews of such suppositories are positive. Patients like not only its convenient form, adjusted dosage and affordable price, but also efficiency. Many women note that after several days of using this drug, the unpleasant symptoms of gynecological diseases disappeared. At the same time, experts remind that in such cases it is not necessary to interrupt the course of treatment. For a lasting effect, you must go through all the prescribed therapy.
We can not say that some patients were unhappy with the results of treatment. In addition, in some cases, women had a problem using candles in the morning, as suppositories quickly melted and flowed out.
Also, patients rarely had side effects in the form of itching and burning in the vagina, but after a short period of time, these symptoms disappeared on their own.
Depanthol treatment for cervical erosion
The substance chlorhexidine (chlorhexidine digluconate) is active against the most common causative agents of female infectionswhich are found in 90% of women suffering from erosive tissue changes in the cervix area. These are bacteria, protozoa and viruses, such as gardnerella, trichomonas, E. coli, treponema, ureaplasma, chlamydia, streptococcus, staphylococcus, neyseriya, herpes simplex virus.
This chemical compound exhibits a rather high activity even in the presence of bloody, purulent or mucous secretions in a patient. However, there is no negative impact on the natural microflora (lactobacilli and bifidobacteria) of the vagina.
The substance dexpanthenol in the patient's body is transformed into pantothenic acid, which is a component of coenzyme A. This process triggers a number of biochemical reactions, which result in acceleration of tissue repair processes in the cervix (regeneration), normalization of metabolic processes in cells.
Contraindications to the use of Depantol is enough few. This drug is used locally, it does not enter the systemic blood circulation, therefore it does not affect other organs. The conditions under which this tool not assigned or canceled:
- Allergy to the components of the drug,
- Children under 18,
Dosage and administration
In the case of therapy of erosive changes in the female genital tract, the only form of the drug is used - vaginal suppositories (candles). It is recommended to remove from packing just before use. Then, in the supine position, a candle should be inserted as deeply as possible into the vagina. This procedure is necessary Once a day, before bedtime. The duration of treatment is from 1 week to 10 days.
In neglected severe cases of the disease, the multiplicity of application of the agent is increased up to 2 times per day (in the morning and before bedtime).
Depantol also applies after cauterization erosion for the early regeneration of cervical tissue as a result of invasive effects.
Use during pregnancy and lactation
Depantol can be used during pregnancy. Substances that are part of this tool have no effect on the development and growth of the baby in the womb. In addition, the drug prevents infection of the fetus during labor, as it passes through the birth canal.
This drug can be used during the period of lactation and feeding an infant with mother's milk. Local application of Depantol does not allow its active substances to penetrate into the systemic circulation and enter the baby’s body.
Side effects Depantol are quite rare, with the patient's hypersensitivity to its components:
- Vaginal mucosa dryness,
- Itching of the vagina and vulva (perineum area),
- Burning during urination and intercourse,
- Redness of the vaginal cavity, perineal skin,
As a rule, all the symptoms of side effects disappear without additional intervention after discontinuation of the medication. Data on a possible overdose of this tool have been reported.
Various forms of release
For the treatment of cervical erosion, a single release form of Depantol is used - vaginal suppositories. Each candle contains 0.016 g (16 mg) of chlorhexidine and 0.1 g (100 mg) of dexpanthenol. The package contains 5 and 10 suppositories.
Also, the drug is produced yet in two formsused in other pathologies:
- Cream for outdoor use
- Spray for outdoor use.
Depantol analogues with identical composition and release form does not exist. The only drug with the same composition is Bepanten plus, but it is available only in the form of a cream for external use and is not used intravaginally.
What is erosion
Erosion of the cervix is a site ranging in size from a few millimeters to 1.5-2 centimeters, red in color, located at the edges of the external os of the cervix that extends into the vagina. Pathology is almost painless and asymptomatic.
The appearance of pathology is influenced by many external and internal factors, but the following are often the main ones:
- non-compliance with the rules of personal, intimate hygiene,
- frequent change of sexual partners
- mechanical injury to the mucous membranes, which often occurs during certain medical procedures, during abortions and difficult births, sometimes with the use of some vaginal contraceptives and self-douching, as well as during too rough sexual contacts,
- hormonal disorders,
- some infectious or inflammatory diseases of the genitourinary system and, as a consequence, reduced immunity.
Early sexual life, pregnancy and childbirth at a young enough age can also trigger cervical erosion.
However, sometimes erosion is manifested by bloody discharge in the middle of the menstrual cycle, especially often after intercourse, soreness during sex or vaginal discharge.
There are several types of pathology:
- congenital - is expressed in redness and displacement of the boundaries of the epithelium lining the cervical canal to the outside. Such pathology appears in girls even in the period of prenatal development and in most cases is self-cured. But there is a likelihood of infection of such erosion, which provokes the appearance of foci of inflammation. It is this form of pathology that never degenerates into a malignant tumor,
- pseudo-erosion –Small red area (about 5 mm), sometimes located outside the cervical canal. This pathology is characteristic of patients with an increased hormonal background, and its danger lies in a rather high risk. reincarnation in cancer. Sometimes this erosion can fester, which indicates the neglect of its development,
- the true - the most common form of pathology, which appears on the cervix in the form of a bright red spot, bleeding when pressed. Often inflamed and festers. True erosion in a woman there is only a few weeks, and then develops into pseudo-erosion due to the growth of connective tissue.
After diagnosing the pathology and determining the type of erosion, the treatment method is determined by the gynecologist.
In the case of congenital and pseudo-erosion, therapy can be avoided and get by with minimal procedures for its eradication. True erosion of the cervix requires conservative treatment, and sometimes surgery.
Conservative treatment is aimed at eliminating the root cause of the pathology, and is also used in the presence of concomitant infectious and inflammatory processes.
About this drug
To date, candles "Depantol" - the most effective tool for the treatment of cervical erosion.
Available vaginal suppository in the form of candles, packaged in plastic packaging, which should be opened immediately before use.
The drug actively affects the pathology even in the presence of purulent and bloody dischargewithout disrupting the natural microflora of the vagina.
The drug has an active effect on the microflora of the female genital organs, as it contains dexpanthenol, which accelerates tissue regeneration, and chlorhexidine, which is a good antiseptic that has antimicrobial and anti-inflammatory effects.
Especially active substances contained in the candles, affect the causative agents of female genital diseases, significantly reducing their number and preventing development.
Candles "Depantol" are used to treat exocervites and vaginitis, as well as a restorative drug after cauterization of erosion, regenerating the mucous membrane of the uterus and vagina.
The drug has anti-inflammatory effect, therefore it is recommended after obstetric and gynecological surgical interventions and after childbirth.
Instructions and dosage
The drug is applied intravaginally - lying on his back, gently inject the candle directly into the vagina, as deeply as possible.
A woman must first carry out all the necessary procedures for personal hygiene to prevent infection.
The dosage depends on the individual characteristics of each patient and the degree of development of the pathology.
The composition of one candle of the drug contains 0.1 g of dexpanthenol, 0.016 g of chlorhexidine and other auxiliary substances sufficient to produce a suppository weighing 3 g.
Candles should be put once a day, preferably at night, and the duration of the course of treatment can vary from a few days to 1-2 weeks.
In fairly complex cases of pathology, the frequency of using candles can be increased up to 2 times per day.
Vaginal candles Depantol
This combined preparation is used in gynecology, has antimicrobial and antiseptic properties, improves tissue regeneration. It has several forms of release, among them - vaginal suppositories. Antiseptic action is local, but, nevertheless, superficial self-treatment is strictly contraindicated. Depantol candles after cauterization of erosion, as an integral part of the rehabilitation period, have proven themselves to be good.
The effectiveness of vaginal suppositories determines the chemical composition of the drug. Outwardly, these are oblong tablets of a light gray color with a yellowish tinge, with a slight depression in the center. Introduced intravaginally, necessary for the productive restoration of mucous membranes. Can only be recommended by a gynecologist for certain gynecological diseases of an inflammatory nature, possibly infectious in nature. Instructions for use determines the following chemical composition of the drug:
Mg concentration in 1 suppositories
The characteristic medicine has several forms of release, but in modern gynecology, suppositories for vaginal and cream use have been particularly well established. After the introduction of suppositories, a stable positive dynamics of the underlying disease is ensured; however, such conservative treatment in practice may provoke an allergic reaction. In any case, there are 5 candles on a blister in one carton box, instructions for use are attached.
Candles Depantol - indications for use
This antiseptic substance in the chemical composition disinfects the microflora, restores the mucous membranes of the vagina. In addition, the drug in the form of suppositories accelerates healing after pathological labors, destroys many forms of bacteria of a pathogenic nature. Depantol is recommended for use in patients in the following clinical pictures:
- acute and chronic vaginitis,
- true cervical erosion,
- rehabilitation after destructive therapies,
- exo- and endocervicitis,
- the postoperative period for accelerated healing of sutures,
If you say a few words about the same cream, it is used externally for breast nipple cracks, tears, as a local antiseptic. The chemical composition of both drugs is identical, but vaginal suppositories act much faster on the pathology, while providing marked changes for the better in the shortest possible time of conservative treatment at home. In gynecology, doctors often choose not a cream, but Depantol suppositories.
Depantol - instructions for use
Candles Depantol are intended as an effective medicine for diseases of the vagina, used intravaginally. Possessing antimicrobial activity, a positive trend is observed at the very beginning of the course of treatment, but the prescribed therapy is indicated to be completed. Use this antiseptic is shown from 7 to 10 days, but if necessary, this time interval is increased to 20 days. For the treatment of erosion requires to introduce a suppository deep into the vagina in the morning and evening.
A similar pharmacological appointment with thrush, and the discharge after suppository Depantol will stop for 2-3 days. The pathogenic fungus reduces its harmful activity, so the unpleasant smell from the vagina, burning and severe itching disappear. Abnormal discharge becomes scarce, soon cease to appear at all. It is better to start the treatment when the periods have ended, and the risk of uterine bleeding is minimal. Intensive therapy must be completed to the end, otherwise recovery is inconclusive, relapses are possible.
It is possible to treat cervical erosion in this way only by the permission of the attending physician and the previously passed diagnosis. To heal mucous membranes and increase the strength of the fibers, you must act strictly according to the instructions. Depantol candles are shown to be stored in a refrigerator at low temperatures, and it is necessary to control the shelf life of the specified drug.
Used to heal wounds, candles do not penetrate into the blood, do not affect the psychomotor reaction and concentration of attention of the patient. Such antimicrobials, like Depantol, have a local effect in the body, so they regenerate mucous membranes without noticeable side effects, or signs of overdose.
When carrying a fetus and during lactation, doctors do not exclude such a pharmacological appointment at home. The use of Depantol candles is appropriate when thrush is progressing against the background of a weakened immunity for productive healing of the mucous membranes. The healing processes are not accompanied by deterioration of the general state of health, the active components of the candles are not excreted in breast milk, they do not overcome the placental barrier. Therefore, restrictions on the use of these categories of patients do not apply.
Interaction with other drugs
Since Depantol suppositories are often prescribed as part of complex treatment, it is important to know about their behavior in the body after a single dose, as the concentration of the active ingredient increases. There is a drug interaction, which can worsen the general condition of the patient, provoke the occurrence and enhancement of side effects. For example, Depantol is incompatible with detergents with anionic substances. It is not necessary to combine in one clinical picture with saponins, sodium lauryl sulfates, sodium carboxymethylcellulose, especially with the introduction of such intravaginal.
In case of intolerance of active components of suppository Depantol, it is better to exclude such an appointment, otherwise the risk of developing and spreading side effects increases. Such a collagen effect is not appropriate in case of disturbed metabolism at the cellular level, in childhood. In any case, only the attending physician can appoint candles for the vaginal mucosa strictly for medical reasons.