How to use doxycycline in cystitis: effectiveness, reviews, contraindications


Doxycycline for cystitis - effective antibiotics, characterized by a sparing effect on the body. Doxycycline tablets have pronounced antimicrobial and antibacterial properties, have anti-inflammatory effect, effectively fight against pathogenic bacteria, significantly alleviating the patient's condition with diagnosed cystitis.

Indications for use

The urologist conducts a comprehensive examination, analysis of the pathogen, and then develops an adequate and most effective treatment.

Doxycycline is recommended for patients suffering from cystitis in the following cases:

  • infectious inflammation of the bladder, occurring in acute form,
  • with chronic form
  • during exacerbation of infection.

Doxycycline begins to act quickly enough, saving patients from such clinical manifestations of cystitis as pain, impaired urination, signs of inflammation

Characteristically, Doxycycline is not indicated in the diagnosed non-bacterial form of cystitis. Even if the inflammation in the bladder is acute, therapy is based primarily on analgesic and antispasmodic drugs.

Dosage and administration

The optimal dosage of an antibiotic is determined by the doctor according to an individual scheme, depending on the age category and the general condition of the patient, the degree of manifestation of the infectious-inflammatory process.

According to the instructions, the drug is recommended to take 1 tablet 2 times during the day, the next day, reduce the dosage to 1 pc.

With chronic cystitis, it is recommended to take 2 tablets per day, divided into 2 doses (for example, in the morning and evening). The maximum daily dosage of doxycycline should not exceed 600 mg.

Doctors recommend taking the medicine at the same time to maintain a constant concentration of active substances in the patient’s bloodstream. Otherwise, the risk of increasing the resistance of the pathogen to the medicinal agent increases, as a result of which the treatment loses its effectiveness or is delayed greatly.

The medicine is recommended to be taken during a meal (use of an antibiotic on an empty stomach is absolutely contraindicated), drinking plenty of pure water (at least 1 cup).

Side effects

In the process of treating cystitis with the drug Doxycycline, there is a possibility of the following undesirable reactions:

  • diarrhea, nausea, vomiting,
  • lack of appetite (up to anorexia),
  • anemia,
  • lowering blood pressure
  • cardiopalmus,
  • muscle and joint pain
  • dysbacteriosis,
  • stomatitis,
  • proctites,
  • vaginal inflammation in women
  • inflammation of the mucous tongues,
  • impaired hepatic function (with prolonged use).

In rare cases, patients complain of bouts of dizziness, decreased visual function, headaches, poor coordination of movements.

Doxycycline has an impact on driving because of the possible overwhelming effect on the central nervous system. Therefore, in the first days of treatment of cystitis, it is recommended to refrain from driving and other actions that require attention, speed of reactions.


Doxycycline for the treatment of cystitis is not prescribed to patients with the following clinical contraindications:

  • leukopenia,
  • porphyria,
  • severe liver failure,
  • lactose intolerance,
  • age up to 12 years
  • patient weight less than 45 kg
  • hypersensitivity and individual intolerance to active substances.

Doxycycline is not compatible with alcohol. Reactions to the combination of drugs with alcohol can be the most unpredictable and extremely dangerous.

Interaction with other drugs

Doxycycline with simultaneous use with oral contraceptives and penicillin antibiotics suppresses their action. Reception of barbiturates, sedatives activates metabolic processes and enhances the action of doxycycline. In this case, you should consult your doctor about the dosage.


Doxycycline overdose cases are rarely recorded in medical practice. At the same time, the patient has a state of general intoxication of the body, the adverse reactions characteristic of the drug are more pronounced. Symptomatic treatment is performed: gastric lavage and sorbents (for example, activated carbon).

Pregnancy and lactation

Doxycycline is absolutely contraindicated for pregnant women and breastfeeding. The active ingredients of the antibiotic enter the child's body through placental blood flow or through mother's milk. As a result, adverse effects and complications may occur:

  • Delays and disorders of intrauterine development.
  • Fatty infiltration.
  • Allergic reactions.
  • Hepatic diseases.

Therefore, if doxycycline is prescribed for a severe form of cystitis in a nursing woman, the child is temporarily transferred to artificial feeding for the period of treatment.

Use in childhood

Doxycycline is strictly forbidden to use for the treatment of patients under the age of 12 years. The active ingredients of the antibiotic adversely affect the growing body, causing a number of undesirable reactions, and entering into a combination with calcium ions, they cause deposits in the bone tissue, skeleton, and tooth enamel.

When and to whom doxycycline is prescribed for cystitis

Doxycycline - not the drug that is included in the primary list of appointments. This is due to the fact that in case of cystitis, urologists prefer to begin therapy with softer and safer means, and only then proceed to the means of modern antibacterial groups. If you skip this point, then a situation may occur in which the patient’s bacterial environment quickly develops doxycycline resistance, and its effectiveness will drop dramatically. So, Doxycycline will be useful when the pathogenic flora does not respond to the use of antibacterial agents of the cephalosporin and penicillin groups.

To whom doxycycline is prescribed for cystitis? First, patients whose bacterial urine culture showed that pathogens are sensitive to this antibiotic. Secondly, the drug will be useful for patients with cystitis immediately after surgery. Such prophylactic use of an antibacterial agent is fully justified, because the patient's body, especially its urinary organs, is now less protected than ever. Doxycycline will help prevent possible infection.

The effectiveness of an antibacterial drug that has the ability to inhibit the growth and reproduction of various bacteria can be noted in relation to such microorganisms:

  • Klebsiella,
  • meningococci
  • Clostridium
  • gonococcus,
  • Streptococcus
  • hemophilic bacteria
  • listeria
  • staphylococcus,
  • enterobacteria.

What is special about this remedy for other antibiotics?

Experts note the main advantage of this drug is a relatively gentle effect on the patient's digestive system, which is an undoubted advantage. This reduces the impact on organs that are not directly involved in the fight against the disease.

To systematize the differences of the drug should be as follows:

  1. Doxycycline to a lesser extent affects the change in microflora. It would seem that this fact is not remarkable, because the main thing that a cystitis patient seeks is to reduce inflammation in the bladder and get rid of the bacteria inhabiting this organ. In fact, this obscure feature is a huge advantage for many patients. So, some women, along with the symptoms of cystitis, note unpleasant sensations in the vagina and other genitals, which are only intensified with the use of antibacterial agents. One can only imagine how glad such a therapy with Doxycycline will be for such patients who are no longer affected by the deterioration of the condition of adjacent organs. Also, the violation of the microflora of the urinary organs can also affect men, especially those who are no longer the first course of antibiotic therapy, and even without a sufficient time interval between them. Doxycycline will not aggravate the situation and will effectively treat inflammation in the bladder.
  2. Very affordable price. Inflammation of the bladder affects all segments of the population. Of course, the availability of funds may affect the speed and effectiveness of treatment, but ordinary patients should also be able to quickly recover from inflammatory processes. Doxycycline is just the drug that even the most economical consumer can afford.
  3. Good absorbability. Any components of the food that the patient absorbs do not affect the effectiveness of the active ingredient Doxycycline. For many patients, this fact matters, because it is not always pleasant to memorize such “trifles” - with which you can drink the medicine and what should be excluded when taking it.
  4. Long term activity of the component Doxycycline, which is stored in the bloodstream for 24 hours. No other drug can boast such success. By the way, this also affects the efficacy of the drug, because patients often fail the regimen of 2-3-4-fold medication. Forgetting to take a capsule once a day is almost impossible.
On average, a drug pack of 10 capsules will cost the patient no more than 30 rubles.

When doxycycline prescribing for cystitis is not effective

If this drug is so good, then why not use it in all patients with bladder inflammation? If we recall, sometimes cystitis is caused not by bacteria, but by viruses, fungi, or does not have an infectious nature of origin at all. In such cases, the use of doxycycline will not be justified. Its use will not have a positive effect on the inflammatory process. Moreover, like any medicament, it has a negative effect on the functioning of a number of organs - the liver and kidneys, which can only aggravate the situation.

How to use

Antibacterial agents are those drugs that must be taken exactly as prescribed by a doctor. Even the summary of the drug is not always true, because the urologist takes into account all the features of this clinical picture - the patient's weight, its comorbidities, previously used antibiotics, the form and type of inflammation in the bladder, etc. Following the exact dosage - the key to successful treatment.

So, how should doxycycline be taken for cystitis? The pharmacological agent itself is considered to be a drug of prolonged action, and therefore it is usually enough to take only one capsule per day. The day in this case should report not from 12 o'clock at night, but from the time of reception of the last capsule. In other words, if a patient drank an antibiotic at 3 o'clock in the afternoon, then the next intake should be at the same time of the next day.

What could be dangerous to change the time of the drug? First, the concentration of the active substance in the patient’s bloodstream must remain unchanged throughout the duration of therapy. Even a slight decrease due to the late intake of doxycycline will lead to the acquisition of resistance to this drug from the bacterium, and the therapy will ultimately be ineffective. Moreover, the further intake of drugs of this group will not make sense, and the urologist will have to prescribe the patient antibacterial agents of another group, to which the pathogens do not yet have resistance.

Secondly, with a decrease in the time between taking the capsules of Doxycycline, the patient may receive an overdose, which will lead to the appearance of side effects. It is such patients who violate the therapeutic course that have a chance to get a negative impression of the treatment of cystitis with Doxycycline.

When taking the medication, it is necessary to stock up with water, since it is necessary to drink Doxycycline capsule with liquid in an amount of at least 1 cup. Also, do not drink Doxycycline on an empty stomach. It is better to choose a meal time for this. Food itself does not affect the absorption of the active ingredient.

How long doxycycline treatment for cystitis on average? In most cases, it is enough to drink the drug for 5 days, but sometimes, for example, for chronic cystitis, this period can be extended.

Side effects and recommendations for admission

All the negative effects are usually associated with long-term use of Doxycycline, and therefore, with a standard course of no more than 7 days, the patient is unlikely to feel them. So, the possible side effects of doxycycline use:

  • dysbacteriosis,
  • pressure jumps or symptoms of hypertension,
  • changes in the composition of the blood, in particular - violation of the norms of the content of eosinophils and leukocytes,
  • manifestations of inflammatory processes in the oral cavity - stomatitis, glossitis,
  • appearance of body aches,
  • disruption of the liver and kidneys,
  • blurred vision, headaches.

This list of side effects is extensive, and therefore for patients at the time of therapy it is strongly recommended to refuse to drive vehicles or perform other actions related to the need for precision movements. Mistakes that a cystitis patient can make are sometimes fatal.

Also, patients may experience an individual photosensitivity reaction. Even a small amount of time spent in the sun, becomes the source of pigmentation and rapid redness of the skin. A visit to the tanning salon, of course, is also forbidden.

If a patient develops an active development of dental tissue, then doxycycline intake may affect the formation of its color. The color of the teeth of such patients for a long period becomes dark, yellow. Most often this applies to patients with cystitis adolescents.

Women taking oral contraceptives should be aware that Doxycycline reduces the effect of such drugs, and the occurrence of pregnancy, which is now undesirable, is likely.

Finally, control over the functioning of the liver and the composition of the blood can be attributed to the recommendations for admission, even if the patient does not note any negative consequences when taking the medicine. This is especially true of those patients for whom doxycycline is not prescribed for the first time. Such preventive measures sometimes help to prevent significant disturbances in the body, the consequences of which are much more difficult to treat.

To whom doxycycline use is contraindicated?

There are a number of people who do not treat cystitis using Doxycycline:

  1. Pregnant and lactating. The drug penetrates through the placenta of the fetus and into breast milk. During pregnancy, the drug can cause pathological changes in the development of the fetus, it causes the development of fatty infiltration in a still unborn child, as well as a significant delay in the skeleton of an organism growing in the womb. This antibiotic has a negative effect on infants and babies. If, in case of cystitis in women with HB, the doctor decided to prescribe Doxycycline, then it is necessary to transfer the baby to artificial feeding for the duration of therapy. If a woman during lactation saw Doxycycline, then the milk in the breast glands must be decanted and poured out.
  2. Patients with lactase intolerance. This violation of enzyme composition is also a contraindication for the use of doxycycline in the treatment of cystitis, since such patients are much more likely to experience side effects from this antibiotic.
  3. Young patients whose age is less than 12 years. Up to 12 years old, the child's body is actively forming, and it is possible to intervene in natural processes very carefully. Doxycycline can change and adversely affect processes. What is this about? In young patients, a skeleton is formed, and the active ingredient Doxycycline reacts with calcium ions and is deposited in the bone tissue during the formation of insoluble complexes.
  4. Patients with low weight. The critical threshold is 45-50 kg of patient weight. Patients with low weight do not tolerate receiving doxycycline, and therefore it is better to replace it with another antibacterial agent.
  5. Intolerance to tetracyclines. If the patient knows about this particular feature of his body, then he is obliged to inform the doctor about it. If the body when taking the drug tetracycline group responds with an allergic reaction, the treatment will not have the desired effect.
  6. Liver failure. The classic case of taking an antibiotic can exacerbate comorbidities is the treatment of cystitis with Doxycycline in the presence of an abnormality in the patient’s liver function. It is impossible to treat one disease to the detriment of other organs.

Doxycycline Reviews

Today you can find many different reviews on the use of doxycycline from cystitis. By the way, this contributes to the low cost of the drug. Due to the wide availability of the drug, it is not surprising that he has both grateful admirers, cured of cystitis, and ardent opponents, who were not helped by the medicine.

There are both positive words of gratitude to this drug, and negative words. In general, if Doxycycline was prescribed by a doctor, then such patients note an improvement in the condition of the urinary organs and are often completely cured of cystitis, including chronic.

Negative reviews of doxycycline in case of cystitis are left by persons who took the drug "according to the advice of friends", as well as with a low qualification of the attending physician. A poor, incomplete study of the clinical picture and the early appointment of Doxycycline without taking into account the individual characteristics of the patient is more likely to lead to another failure in the treatment of cystitis.

How and with what doxycycline can help with cystitis?

This drug belongs to the synthetic drugs group tetracycline. It can be characterized by a rather large range of action against bacteria. It negatively affects gram-positive flora. It includes, in scientific terms, various "cocci", that is, globular bacteria: staphylococci and streptococci, as well as clostridia and Listeria.

Also, the drug has a negative effect on gram-negative microbes, such as meningococci, gonococci, hemophilic infections, enterobacteria of various types, E. coli and a number of other bacteria. The flora is inhibited, being resistant to the antibiotics of the most famous groups - penicillins, cephalosporins.

Doxycycline has a number of beneficial properties for cystitis:

  1. The speed of action.
  2. Wide coverage of harmful bacteria.
  3. Help for patients with not only cystitis, but also other serious bacterial diseases.
  4. Long lasting effect.
  5. Easy suction.

This drug will help avoid visiting the doctor and prevent the patient from entering the hospital.

Instructions and application

You can use this drug only after consulting a doctor, because when taking antibiotics is especially important to observe the correct dosage. A full examination is required from a health worker, a man from a urologist, a woman, respectively, from a gynecologist. Doxycycline is usually taken 1 time per day, and in the case of acute illness - 2 times a dayin the morning and evening. The course ranges from several days to a month. Overdose is also possible. Its main symptoms are:

  • Nausea, vomiting.
  • Coordination problems.
  • Nebula of consciousness, lethargy.
  • Fainting

If these symptoms appear, you should immediately use products that have an antacid effect (even classical activated carbon will do) and call an ambulance.

Prevention of cystitis

Based on all the above, we can conclude: Doxycycline is a strong proven drug against cystitis and other bacterial diseases. But it is always important to keep in mind the need to follow the instructions, and in case of any change in state of health for the worse - to call the doctor immediately. But the most correct approach to the problem is the prevention of cystitis:

  1. Do not stay long in the cold, as hypothermia is the most common cause of cystitis.
  2. Hygiene. You just need to follow basic rules of hygiene (shower, the use of individual toilet products).
  3. Constant movement. Do not linger in one place, and in the case of sedentary work - systematic gymnastics or a walk.
  4. Do not self-medicate. Even a slight violation of the dosage of antibiotics can lead to disastrous consequences. And even more so you never need to turn to various healers, drink "magic folk remedies", the recipes of which are full of various sites on this topic.
  5. Periodically undergo a comprehensive examination, once a year - in two to go to a urologist or gynecologist, even absolutely healthy people. And having any predisposition to cystitis in general as often as possible.

If you take these simple rules seriously, you can make your life easier for yourself and never face such an unpleasant disease as cystitis.

Short description

To the action of "Doxycycline" are resistant to the neuropurulent bacillus, proteus and bacteroids. These are causative agents of nosocomial infections. The drug is active against the following microorganisms:

  • staphylococcus,
  • Streptococcus
  • Clostridium
  • neisserii (pathogen gonorrhea),
  • E. coli
  • causative agent of dysentery,
  • salmonella,
  • treponema (causative agent of syphilis),
  • mycoplasma
  • chlamydia.

The drug is effective in most inflammatory diseases of the respiratory and urinary tract.

What is the drug for?

In humans, there is a constant microflora. It is divided into beneficial and opportunistic. The latter is located on the skin, in the tonsils and intestines, is present on the mucous membrane of the urinary tract. Conditionally pathogenic microorganisms can cause inflammatory diseases in the case when the necessary bacteria cease to “restrain” their growth and reproduction. This happens when immunity is weakened (hypothermia, cold) or dysbacteriosis.

Other pathogens are infectious pathogens. For their introduction into the body requires contact with the patient or with the carrier of the virus. In a healthy person, such microorganisms are normally not detected. These include pathogens of syphilis, gonorrhea, dysentery, salmonella.

The disease occurs with a local inflammatory reaction and recognizable diagnostic symptoms. The condition is characterized by generalized systemic exposure to toxins, manifested by the clinic of infectious intoxication. Observed symptoms such as:

  • fever,
  • chills,
  • muscle aches,
  • pain in the eyeballs
  • weakness,
  • dizziness.

Local symptoms disrupt the body, common - can be fatal due to severe intoxication. The use of the antibiotic doxycycline for the treatment of such diseases is due to the need to destroy the bacteria.

Relevance to cystitis

Inflammation of the mucous membrane of the bladder is called cystitis. Clinically manifested dysfunction of the body and local changes. General toxic effects are rare, only if complications occur. Symptoms of cystitis are the following characteristic symptoms:

  • pain when urinating,
  • cutting after emptying
  • frequent or false urges,
  • change of color, smell of urine and its transparency,
  • leukocytosis, bacteriuria in urine analysis.

The danger of untreated cystitis is not only in the addition of complications, such as pyelonephritis and urethritis. Bacteria that provoke inflammation on the mucous membrane, eventually migrate to the inner layer of the bladder. However, they become difficult to achieve for drugs. Pathogens do not just live in the submucosal layer, there they support inflammation. This is manifested by signs of chronic cystitis.

The danger of this condition is in violation of the function of the bladder, leading to stagnation of urine, the formation of inflammatory cicatricial changes in the walls of the organ. Chronic dysfunction leads to a decrease in local immunity, easy adherence of specific infections (syphilis, gonorrhea, trichomoniasis), even through domestic infection. Combined infection causes intoxication, purulent processes.

For women, untreated cystitis is dangerous in terms of fertility and childbearing ability. The disease can provoke inflammation and adhesions in the internal genitals, which will lead to infertility.

Doxycycline in women with cystitis prevents these effects. For men, the disease is dangerous development of prostatitis, urethritis, also leading to infertility.

Therefore, the treatment of inflammation of the bladder should be made in accordance with the following principles:

  1. Timeliness.
  2. The correct selection of antibacterial drugs (such that are susceptible to infection).
  3. Exact adherence to the dosage regimen, dosage and duration of the course.

Checking the effectiveness of doxycycline in relation to the pathogen is carried out by the study of urinalysis after 5, 7 and 10 days from the start of treatment. Additional control is made a few weeks after clinical recovery. This is necessary to exclude the transition of cystitis in the recurrent stage.

Doxycycline has a fast bacteriostatic effect on most pathogens that can cause cystitis. By destroying infectious pathogens, it contributes to the cessation of inflammation, prevents the spread of the process and the formation of complications. Also, the drug does not allow pathology to acquire a chronic form.

Prohibition of use

Antibiotic therapy has no absolute contraindications, except for allergies to a particular drug or class. Renal or hepatic impairment does not prevent the use of antibiotics, they only require dose adjustment. Medications may be prohibited for use during pregnancy, lactation, and until a certain age the child. Doxycycline has the following contraindications:

  • hypersensitivity to the drug or its intolerance,
  • severe liver failure
  • leukopenia,
  • pregnancy,
  • children's age up to 14 years.

Contraindications in the appointment of "doxycycline" are relative, except for intolerance. Correction of dosage if necessary therapy with this antibiotic is allowed.

The drug is actively used to treat various infectious diseases, due to availability, a wide range of actions and a small number of contraindications.

Negative effects

With antibiotic treatment, adverse reactions are possible. This is due to the detrimental effect on the microflora, which is the main expected effect. At the same time, along with infectious agents, the necessary bacteria of the intestine and genital tract die. The use of antibacterial therapy causes dysbacteriosis and, as a result, diarrhea, constipation, dyspepsia.

Women may develop disvaginosis, which is manifested in various secretions with an unpleasant odor. Such phenomena are due to the death of the beneficial microflora of these organs and the growth of pathogenic strains. This side effect is adjusted by the appointment of probiotics and antifungal drugs.

Side Effects of Doxycycline:

  • dyspepsia,
  • photosensitization
  • allergic reactions
  • neutropenia,
  • anemia,
  • transaminase enhancement,
  • discoloration of tooth enamel.

Usually the drug is well tolerated. These side effects occur with prolonged use. They do not reach dangerous severity and quickly normalize after the end of treatment.

How to properly treat, scheme, dosage, duration

Patients starting the treatment with the prescribed drug should have an idea how to take doxycycline correctly for cystitis. The drug is available in capsules of 100 mg. This dosage form is due to the need to reduce the impact on the gastric mucosa. Substance begins to be absorbed in the duodenum after the capsule shell dissolves.

The daily dose of the active substance (doxycycline) - 200 mg. For children weighing more than 50 kg, it is 4 mg per kg of body weight per day. The medicine should be taken at regular intervals. Be sure to take the drug after meals. The capsule is swallowed whole and washed down with plenty of water. The course of treatment from 10 to 14 days. You should drink plenty of fluids to remove the antibiotic breakdown products.

When treating cystitis with Doxycycline, repeated urinalysis tests are required for leukocytosis, turbidity, density, and the presence of red blood cells. That's right, if the first study is done no earlier than 5 days from the start of therapy.

Actions in case of overdose

The rules of drug intake should be complied with in accordance with the instructions. If they are exceeded, negative effects may occur. The clinical symptoms are as follows:

  • nausea,
  • vomiting
  • rash,
  • headache,
  • impaired reaction to light.

If there are signs of overdose, stop taking the drug. It is necessary to wash the stomach and ingest sorbents (activated carbon). You should definitely call an ambulance, because the clinical manifestations can increase and lead to complications.

How doxycycline interacts with other drugs

When prescribing any drugs, be sure to know about their interaction with other drugs. "Doxycycline" is not used in conjunction with antacids based on aluminum, calcium and magnesium salts, as well as with medications for the treatment of anemia (iron).

Barbiturates reduce the half-life of the antibiotic, which impair its effectiveness. Combination with penicillins reduces the effect of both agents. Estrogen-based drugs (oral contraceptives) help to increase the frequency of bleeding, as well as reduce the reliability of contraceptive drugs for the period of "Doxycycline".

What replace the drug

If it is necessary to take an antibacterial agent from the tetracycline class, the replacement of "doxycycline" can be made in two directions. The first is the choice of such an active substance.

Another way to replace - the selection of the trade name of the substance. Glycocline, methacycline and oleandomycin - oletethrin are also included in the tetracycline class. From direct substitutes, various doxycyclines are used, such as: "Vibromycin", "Doxybene", "Doxy-M-Ratiopharm", "Doxycycline-Soluteb", "Unidox".

What do experts and patients think of “doxycycline”?

Antibiotic therapy allows you to treat a variety of infectious and inflammatory diseases. To choose the right drug, you need a smear from the focus of inflammation or a study of urine to identify the pathogen and then identify its sensitivity to antibiotics. This takes some time, during which serious complications can develop, even with cystitis. Therefore, a wide-spectrum antibacterial drug is required for outpatient therapy. Also, it should be as safe as possible when receiving, have a wide therapeutic window. This is the difference between the active dosage used in therapy and that which can cause dangerous side effects to be toxic.

"Doxycycline" is used for cystitis, has a broad spectrum of antimicrobial action and high safety profile. According to reviews of patients, the drug can help with various forms of pathology and is well tolerated, is widely represented in the pharmacy chain and has an affordable price. It should be noted that manufacturers produce the drug at different retail prices. It depends not only on the name of the company and the importance of the brand, but also on the raw materials and the degree of purification.

The appointment of "Doxycycline" with cystitis has positive feedback from doctors (urologists, general practitioners, surgeons). The drug fully justifies the expectations of therapy: quickly relieves symptoms, leads to complete recovery, confirmed by control urine tests. Adverse reactions are rare, mainly associated with individual intolerance. To avoid such an action fails any drug.

What is this means

The drug has a broad antimicrobial effect on gram-positive microorganisms that change color when using a special dye:

  • staphylococcus,
  • streptococci
  • Clostridia (conditionally pathogenic anaerobic bacteria, enter the normal flora, but with excessive reproduction can be a health hazard, can cause clostridioses - botulism, tetanus, toxicoinfections, etc.),
  • actinomycetes, with a gram-positive reaction, have a structure close to gram-negative (fungal microorganisms that have pathogenic forms that create health problems),
  • Listeria (intracellular parasitic microorganisms, may be the cause of abscesses, meningitis).

Also affect the gram-negative flora:

  • meningococci
  • gonococci (pathogens of gonorrhea),
  • Klebsiella (can cause pneumonia, urogenital diseases, sepsis, acute intestinal infections),
  • enterobacteria,
  • hemophilic bacterium (is the cause of the occurrence of acute conditions accompanied by the development of ulcers in various organs, lesions of the respiratory system and the central nervous system).

    Suppresses the activity of flora, which is immune to penicillin and cephalosporin antibiotics.

    Disturbance of the normal flora with doxycycline occurs to a lesser extent than with other antibiotics.

    Who is he assigned to

    More often, doxycycline is prescribed to patients with various pathologies of the respiratory tract (in case of bronchial asthma, pulmonary infectious lesions, and other painful conditions caused by various microorganisms).

    Doxycycline should be used only as prescribed by a doctor.

    With urogenital infectious diseases, including urinary and genital pathologies.

    Diagnosis of cystitis

    A full range of procedures for examination is usually prescribed for the chronic course of the disease, when the symptoms are mild or in the absence of the result of the treatment.

    Most often, cystitis has an infectious nature, and antibiotics are used to treat it.

    The purpose of diagnosis is accurate diagnosis, with the bacterial form of the disease - the identification of the pathogen.

  • General urine analysis.
  • Sowing on bacteria.
  • Urine research according to Nechyporenko.
  • PCR-diagnostics (Polymerase chain reaction - a method that allows to detect infectious diseases with great accuracy).
  • Cystoscopy (examination of the internal surface of an organ with the help of an endoscope, carried out after the disappearance of acute symptoms).
  • Ultrasound of the genitourinary system.
  • Biopsy material may be taken.

    Women need a thorough gynecological examination to detect diseases of the organs that contribute to the development of secondary cystitis.

    In which case can assign doxycycline

    When diagnosing cystitis, there are several forms of the disease:

  • chronic (signs of disease are less pronounced),
  • primary (as an independent disease),
  • secondary (accompanies another disease),
  • bacterial (caused by infectious microorganisms),
  • non-bacterial (is due to irritation of the walls of the bladder).

    The causative agents of inflammation of the bladder can be staphylococci, streptococci, E. coli and other pathogens. At the same time, it can develop in combination with other diseases, respectively, the paths of infection can also be different and depend on the nature of the underlying disease (with blood flow, lymph, descending, ascending).

    Unidox Solutab - a common analogue of doxycycline

    If the diagnosis confirms the development of non-bacterial cystitis, antibiotics are not prescribed. In this case, the treatment will be aimed at alleviating pain and spasms, in most cases, the inflammation is quite fast. The difficulty lies in the fact that the symptoms of these two types of cystitis do not practically differ, therefore it is required to conduct a survey and pass tests for the identification of the pathogen or to confirm its absence.

    Unidox Solutab in the treatment of cystitis

    Cystitis is characterized as an inflammatory process in the body. A clearer name is inflammation of the bladder. The treatment is aimed at suppressing the action of the microorganisms that caused the disease. Treatment is chosen strictly on doctor's prescription. This is especially true of antibiotics. If you get rid of inflammation in time, the illness will pass very quickly. The chronic form causes painful symptoms several times a year, interferes with the normal flow of life. Unidox Solutab can help in all this.

    Symptoms of cystitis

    The brightest of them are:

  • Burning and pain when urinating.
  • Discomfort in the genital area.

  • Temperature rise,.
  • The feeling of constant fullness of the bladder (a feeling of being unable to fully urinate).
  • The appearance in the urine bleeding.
  • Frequent urge to urinate.

    Causes of illness

    In girls, cystitis appears with the appearance of the first menstrual period, vitamin deficiency. Cystitis develops when girls do not comply with hygienic norms, synthetic underwear in the cold period of time. Impact on the development of cystitis weak immunity, undermined by frequent acute respiratory diseases.

    In old age, dyshormonal changes, hypothermia of the body, non-compliance with the rules of personal hygiene (especially the genitals), irregular and delayed urination can be the cause of the disease. Causes are infections in organs located near the genitals, immunodeficiency, vitamin deficiency.

    Tablets for complete and instant healing does not exist. This is due to various types of pathogens.

    There are a lot of parasites that can cause cystitis:

    It is difficult to isolate and determine the causative agent; a wide examination is necessary, including analyzes. Antibiotics have different strengths of action, direction and level of susceptibility by the body.

    Unidox Solutab - spectrum of action

    Cystitis uses various antibiotics. According to statistics from medical sources in the first place is Unidox Solutab. The antibiotic belongs to the third generation cephalosporins. Pharmacological affiliation is a tetracycline group.

    The drug has a strong bactericidal effect. The substance produces a strong effect on the microflora of the affected organs within a full day, therefore it is recommended to use one tablet during the day. The course of medication is a week.

    The benefits of pills

    The drug differs from other similar tablets by the active action of doxycycline. The generic name of the drug, recognized as international, is most commonly used by the people - doxycycline. Usually the substance is a capsule. In the case of Unidox Solutab, doxycycline is in the form of a monohydrate, more often it is contained in the form of hydrochloride. The tablets dissolve, reaching the intestine.

    There are several advantages of the drug:

    1. Actively acting on the cause of the disease, the substance dissolves in the area of ​​maximum absorption by the tissues.
    2. The loss of beneficial properties of the substance is practically excluded.
    3. The occurrence of side effects (stomach diseases) is not observed.
    4. The patient has the opportunity to choose a convenient method of taking the pill: simple swallowing, taking after dissolving in water.

    Cons medications

    The cost of Unidox Solutab is higher than similar drugs. Sometimes the difference comes up to 20 times. This leads to low-income patients prefer cheaper medicines.

    Reviews Elena N. 42 years: The price of the medicine is higher compared to peers. But unidox solutab is required less in quantity and course of administration.

    It is clear that not always taking such drugs ends with a negative result. The same disease in different patients requires an individual treatment regimen.

    The composition of the drug and the use of

    Unidox Solutab is a member of the antibiotic group. A number of drugs - tetracycline. One tablet contains several parts of the content, which can be divided into two large subgroups: active and auxiliary. Pure doxycycline is active.

    To auxiliary elements:

  • hyprolosis 18.75mg,
  • microcrystalline cellulose (MCC) 45 mg,
  • magnesium stearate 2mg
  • hypromellose,
  • saccharin 10 mg,
  • lactose monohydrate 25mg
  • colloidal silicon dioxide (anhydrous).

    Drug pharmacology

    Doxycycline, which is the main element of the unidox solutab, stops the growth of bacteria that cause the development of cystitis.

  • pneumococci,
  • enterococci,
  • moraxella,
  • meningococci.

    No sensitivity to the action of the drug gonococci.

    The drug is active against such microorganisms:

  • leptospira,
  • rickettsia,
  • spirochetes,
  • chlamydia
  • borrelia,
  • mycoplasmas
  • some actinomycetes.

    The processes taking place while taking the medicine

    The unidox solutab tablet enters the body with water and is absorbed by the intestinal walls. The action begins approximately 1, 2 or 3 hours after ingestion. In blood, tissues, there is a maximum level of doxycycline. In the cerebrospinal fluid, in the bile, the amount of medication is 20-25% more than in the blood systems. The withdrawal of the substance from the body takes quite a long period: half of the dose taken out in 20 hours.

    The drug actively interacts with concomitant drugs, so sometimes it is included in the complex recommended by a specialist. The treatment gives the result not only in getting rid of cystitis, but also cleansing the face from acne, improving in the condition of the glands.

    Reviews Tatiana E. 28 years old: The skin becomes smooth, clean, healthy.

    Independently choose the interaction can not be. The action has very complex effects, so self-treatment can lead to serious illnesses.

    Correct application

    Tablets for the treatment of cystitis is recommended to take standing in full growth. It is recommended to drink a maximum amount of water - a glass. Water will protect the esophagus and prevent irritation in the intestinal mucosa and stomach. To take the medicine, the time convenient for repetition is chosen: at bedtime, in the morning, in the afternoon.

    Responses of Maria V. 32 years: Evening medication is not recommended. At night, unpleasant sensations will begin to appear that will disturb the night's rest.

    A rested patient spends the day easier, more imperceptibly, an internal improvement of the patient’s condition flows. Take 1 tablet for treatment of cystitis at the same time. Approaching this time to eat is not necessary. Change the dose during the course of treatment can not be either up or down.

    Treatment with pills is recommended not to accompany the rest in the open sun. Direct exposure to the sun on the patient’s body should be avoided.

    In case of overdose, symptoms similar to liver disease are noted:

  • Vomiting.
  • Fever.
  • Jaundice.
  • Azotemia and others.

    Doctors spend washing, give a large amount of liquid for drinking and cleaning the stomach. Activated carbon and laxatives are chosen as medicinal assistants.

    Internal processes

    Absorption occurs quickly with an increased degree of absorption. Food intake during the course practically does not change the action of the antibiotic. The active substance combines with plasma proteins, enters the tissues of internal organs. Part of the drug is subject to metabolism. Drug withdrawal occurs in approximately 22-24 hours.

    Adverse negative symptoms

    In the treatment of cystitis with an antibiotic may be a manifestation of side effects. Some organs and systems react negatively to tablets.

    Symptoms of such adverse reactions may be different:

  • The manifestation of a little nausea.
  • Frequent vomit in the mouth.
  • Rezi in the abdomen.
  • Diarrhea.
  • Inflammation of the pancreas, colon.
  • Violation of the intestinal microflora.
  • Increased pressure and dizziness associated with it.
  • Violation of the liver.
  • The change in the state of tooth enamel (color change).

    Testimonials of Lyudmila V. 29 years old: Headaches and heaviness in the liver appeared during the admission. Olga I. 26 years old. The treatment of unidox resulted in constipation.

    All taking pills talk about the relief of side effects when taking a large amount of water. Need to drink almost all day.

    Recommendations for contraindications

    Unidox Solutab can not be used during pregnancy at any time. A strong active substance can easily penetrate the fetus and impair its growth and development. Especially negative violations are noted in the structure of the bone tissue of the fetus. Pregnant grass help. Physical therapy will make the procedure safe for the child and mother.

    It is not recommended to take antibiotic at the same time as alcoholic beverages. The action of antibiotics is activated by alcohol and increases the toxicity of the effects on the liver. Refusal from the recommendations of experts can lead to toxic type of hepatitis. Alcohol reduces the therapeutic effect. You can take it after 7-8 days after the end of the course of treatment.

    Treatment of cystitis in children

    The dose of antibiotic is calculated by the weight of the child and age. The separation is carried out by weight from 50kg and above, and age from 8 to 12 years and older. Under 8 years old the drug is prohibited. For children, the best option is to dissolve in water, in liquid form. It is not necessary to make a large amount, 20ml is enough. During the day, water intake is needed to increase.

    Antibacterial action of Unidox Solutab has the desired effect and result. When choosing for the treatment of this drug should examine the individual characteristics of the person, check for tolerability of the components of the therapeutic substance. The drug has a clear dosage and selection. An antibiotic should not be used for a long period, it can make an imbalance in the body, weaken it to other infections and diseases.

    Description and instructions doxycycline

    Doxycycline is an antibiotic drug that belongs to the tetracycline group. This drug is distinguished by a rather wide spectrum of antibacterial actions, which allows it to block the reproduction process of microorganisms in the cell. The list of causative bacteria that may differ in particular sensitivity to the action of "doxycycline", in general, almost coincides with the list for "tetracycline". One of the main features of this drug can be called the fact that the drug has an active inhibitory effect on intracellular pathogens, among them - chlamydia. rickettsia, mycoplasma. Comprehensive treatment, which involves the simultaneous use of drugs such as quinine and doxycycline, is especially effective for diseases such as, for example, malaria infection. Among other distinctive features of the drug can also highlight its high activity, almost complete absorption, as well as the duration of its action. As a result, taking this drug in therapeutic doses may be slightly less effective than taking other antibiotics of this group in similar doses. Taking the drug does not adversely affect the natural intestinal microflora, as other tetracycline drugs affect. Among the indications for treatment with "doxycycline" are various infectious diseases that are caused by microorganisms, and are particularly sensitive to the nature of its bacteriostatic effects.

    Doxycycline is made in the form of tablets, as well as capsules. In accordance with the annotation to the drug, its dosage, as well as the duration of the course of administration should be determined only by the attending physician. In addition, a qualified physician may develop a plan for taking the drug at the same time as other drugs, antibiotics. Treatment with this drug is not indicated for patients suffering from severe kidney and liver damage, as well as the hematopoietic system, a number of autoimmune diseases, as well as children during the period of changing milk teeth, pregnant and lactating women.

    Side Effects and Doxycycline Overdose

    It is known that all types of antibiotics intended for internal use - in the form of solutions, tablets, as well as suppositories or injections - are distinguished by a systemic nature of their action. For this reason, virtually any system of the human body, or an organ, can react to the drug Doxycycline. This may be the cardiovascular, digestive, musculoskeletal, nervous system. For example, taking this drug is not indicated for children during the period of changing milk teeth, precisely because it can disrupt the state of tooth enamel or cause the formation of tartar.

    If there was an overdose of "doxycycline", then the first thing that needs to be done is to promptly remove the excess of this drug from the patient's body. This can be done, for example, in the process of washing the stomach, or by taking activated charcoal. In addition, the patient may require proper medical monitoring of the condition in order to select and administer modern symptomatic therapy.

    Doxycycline application rules

    The causes of cystitis (inflammatory processes in the tissues of the bladder) are different. Irritation of the mucous membranes can occur after drinking alcohol or irritating food (spicy, salty), in the presence of sand or stones (urolithiasis), as a result of injuries, surgical interventions.

    Doxycycline is resorted to, if necessary, to cope with the bacterial form of the disease.

    The most common cause of inflammation is a bacterial infection. And in this case, treatment necessarily includes taking antibiotics. Doxycycline is one of the antimicrobial agents prescribed for cystitis.

    What is a drug

    Most often, when inflammation of the bladder by bacteriological analysis, E. coli, streptococcal or staphylococcal infections are detected. Less commonly, inflammation accompanies sexually transmitted infections - gonorrhea, chlamydia, trichomoniasis and mycoplasma.

    Doxycycline is a semisynthetic antibacterial agent of the tetracycline group. Available in capsules of 100 mg. It is characterized by a wide range of antimicrobial action: it has a detrimental effect on gram-positive flora (staphylococci and streptococci, clostridia, actinomycetes, listeria) and gram-negative microbes (meningococci, gonococci, hemophilic infection, klebsiella, chromsiella, chypsophilia, gums, klebsillie, spermidia, klebsridki, klestridii, klestridii, klestridii, klebsridii, klebsridii) It inhibits flora that is resistant to antibiotics of other groups - penicillins, cephalosporins.

    The drug is able to fight many germs and bacteria.

    The advantages of the drug in comparison with other means of the tetracycline group:

  • It suppresses the beneficial intestinal bacterial flora less.
  • Better absorbed.
  • Acts longer.
  • It has a stronger therapeutic effect (10 times smaller doses are used for treatment, and the therapeutic effect lasts longer).
  • It is taken once a day.

    Scheme and features of admission

    Dosages are determined by the doctor for each patient individually, taking into account the form and severity of inflammation. Usually, in acute cystitis for adults and children over the age of twelve (weighing more than 45 kg), the antibiotic is prescribed twice a day on the first day and once a day on the next day.

    Пить антибиотик при хроническом цистите рекомендуется по 2 таблетки в сутки (лучше в два приема) на протяжении всего терапевтического курса. The therapeutic course lasts on average up to 5 days, is also set by the doctor individually.

    Intracranial pressure may increase if the drug dosage is not followed.

    As a result of taking the antibiotic, the mucous membranes of the digestive organs are irritated; therefore, it is recommended to take the medicine along with food and drink a large amount of liquid.

    Maximum per day you can drink 600 mg of doxycycline for gonococcal infection and 300 mg for other infections. If these doses are exceeded, signs of overdose and drug poisoning may develop - neurotoxic reactions that manifest themselves:

  • Nausea and vomiting.
  • Cramps.
  • Increased intracranial pressure and the resulting confusion of consciousness.

    When these symptoms appear, immediate withdrawal of the drug, gastric lavage is required. To prevent and reduce the absorption of the drug, magnesium sulfate, antacid preparations, activated carbon are prescribed.

    What adverse reactions to expect

    The list of side effects of the drug is extensive. Doxycycline provokes side effects from virtually all body systems, organs of the senses.

  • Reception means can cause disruptions in metabolism and the development of anorexia. On the part of the digestive system, nausea and vomiting, diarrhea, abdominal pain, colitis and enterocolitis, esophagitis, dysphagia, gastritis and peptic ulcer can occur.
  • With the passage of a therapeutic course, blood pressure may decrease, heart rate rises. Possible functional disorders of the hematopoietic system: increased destruction of red blood cells (hemolytic anemia), a decrease in platelets (thrombocytopenia) or leukocytes (leukopenia), increased eosinophilia (eosinophilia).
  • Sometimes there is a violation of the liver, cholestasis. Arthralgia and myalgia may develop (pain in the joints and muscles, respectively). In the urine increases the concentration of nitrogen.
  • Frequent adverse reactions include dysbiosis, inflammatory processes in the mucous membranes of the mouth (stomatitis), tongue (glossitis), rectum (proctitis), and vagina in women (vaginitis).

    Patients taking doxycycline may complain of tinnitus, blurred vision, headache, and loss of appetite, triggered by an increase in intracranial pressure. There is dizziness, imbalance and coordination.

    Sometimes when taking Doxycycline, you may experience liver problems.

    Due to the high risk of developing side effects, taking an antibiotic is only needed by a doctor.

    Antibiotic is contraindicated

    Doxycycline is not assigned:

  • Patients with lactase deficiency.
  • With lactose intolerance.
  • Patients with leukopenia.
  • With porphyria.
  • When liver failure (severe).
  • Patients with intolerance to doxycycline and other tetracycline antibiotics, auxiliary components of the drug.
  • Children under the age of 12 and / or lighter than 45 kg.
  • For the treatment of pregnant women.
  • Women during breastfeeding.

    Doxycycline is prohibited to take during pregnancy.

    The drug is not used in pediatric practice, since the active substance, interacting with calcium ions, forms insoluble complexes that are deposited in the bone tissue (skeleton, tooth enamel, dentin).

    In case of cystitis, an antibiotic is not used in pregnant women because of the toxic effect on the fetus: the drug causes a delay in skeletal development, fatty infiltration of the liver. If it is necessary to take an antibiotic for a nursing woman, feeding for the period of therapy is stopped.

    What antibiotics to drink with cystitis: names, descriptions

    Those who have already experienced a disease such as cystitis, know that this disease is accompanied by many unpleasant symptoms. Not only women suffer from cystitis, but also men, and they are prescribed the same medications for treatment. In acute forms of the disease, antibiotics for cystitis are prescribed in cases where the pathogens are microbes and bacteria.


    In order to properly prescribe treatment, the doctor first writes out a referral for tests, since only the urine sap of the urine will help determine the causative agent of the disease and the group of antibiotics that will help to destroy it. Most of the drugs used treat not only cystitis, but also pyelonephritis and urethritis. In chronic forms, antibiotics may be prescribed for prophylactic purposes. If the cause of the disease are not microorganisms, the treatment is carried out with other medicines.

    When prescribing antibiotics, doctors are guided by the following principles:

  • the causative agent of the disease has a high sensitivity to such drugs and quickly dies,
  • the active substance is concentrated in the urine, thereby increasing the effectiveness of treatment,
  • the risk of side effects is minimal, the drug is safe for the patient (this is especially important for pregnant women).
  • the drug is administered orally and not by injection (important for children).

    Pregnant most drugs can not be taken. In order not to harm the woman and the fetus, you can not self-medicate, it is necessary to consult with your doctor. Currently, there are herbal preparations that will help cure cystitis. Pharmacists can offer antibiotics that are effective but safe for pregnant women.

    Most drugs that are prescribed to both women and men have a wide spectrum of action, thanks to which they can destroy several types of bacteria at once. It is usually recommended to take the medicine by one of three methods: a single dose of the medicine, a three-day course and a week course. The most commonly prescribed antibiotics for cystitis will be described below.

    Prolonged treatment is prescribed to people at risk. These include pregnant women, men with acute cystitis, women after 65 years, diabetics. They may also prescribe a weekly course of treatment for recurrence of cystitis, if the woman was ill in adolescence, if the patient's mother had chronic cystitis. This technique helps to prevent the recurrence of the disease.

    Diabetics are a group of people who are prescribed long-term treatment.

    Prolonged treatment is prescribed to people at risk, these include pregnant women.

    Men with acute cystitis are prescribed long-term treatment, as they are at risk.

    The tool is available in the form of granules, which are easily dissolved in water. Before taking them diluted in 1/3 cup of warm water. One sachet contains a dose for a single dose - 3 g.

    Men and women with mild disease are prescribed a single dose of Monural (1 sachet before sleep on an empty stomach). For severe forms - 1 sachet per day for 2 days. Children older than 5 years are also prescribed a single dose, but in the amount of 2 g.

    Nolitsin - a drug containing a substance from the group of quinolines. It is effective against gram-negative aerobic bacteria and some strains of gram-positive microorganisms. When taking Nolicin substance concentrates in the urine, which helps to actively fight the cause of inflammation.

    Nolitsin is used to treat chronic and acute cystitis, pyelonephritis and pyelitis, as well as chronic prostatitis in men. Available in the form of tablets, film-coated. Before use, Nolitsin does not need to grind.

    Nolitsin is effective against gram-negative aerobic bacteria and some strains of gram-positive microorganisms.

    It is recommended to drink it an hour before meals or two hours after. The dose is determined by the doctor, but usually for both men and women, it is 1 tablet 2 times a day. In case of inflammation of the lower urinary tract, the course of treatment with Nolitsin is 3 days, the upper - 7 days, recurrent chronic diseases - up to 12 weeks.

    The drug has a bactericidal action from the group of nitrofurans. It copes well with gram-positive and gram-negative bacteria such as streptococci, staphylococci, Salmonella, enterobacteria, destroying them at the cellular level.

    The tool is intended for the treatment of infections and inflammatory processes of the urinary system. These include pyelonephritis, cystitis and urethritis.

    Furadonin is also used for urological operations, with cystoscopy, catheterization.

    Drink pills recommended 3-4 times a day, drinking plenty of water. A single dose for an adult should not exceed 0.3 g, daily - 0.6 g. The course of treatment for acute forms of the disease is 7–10 days, for prophylaxis - 3–12 months. In the latter case, the doctor prescribes the dosage.

    Choosing an antibiotic for cystitis, you need to rely only on the recommendations of the doctor.

    Overview of the drug

    Doxycycline is a broad-spectrum antibacterial agent. Available in hard yellow capsules, inside the powder is yellow-green in color with white patches, which is the norm.

    • Staphylococcus,
    • streptococcus,
    • enterobacteria,
    • E. coli
    • Protea,
    • Klebsiella,
    • mycoplasma
    • chlamydia.

    Purpose for inflammation of the urea

    In primary cystitis, the drug is not prescribed. First, antibiotics are prescribed for a milder effect (penicillins, cephalosporins). If you immediately apply doxycycline, it will cause addiction, not only to this tool, but also to other groups of antibiotics.

    Indications for appointment women:

    • acute form of cystitis with severe course, complications,
    • chronic urinary tract infection in the acute stage,
    • if the bacterial culture of urine has determined the sensitivity to the active substance,
    • cystitis developed after surgical treatment.

    Doxycycline use is not justified if inflammation is caused by viruses, fungal flora, or the infectious cause of the disease has not been established.

    To whom the drug is contraindicated

    The drug is contraindicated in severe functional liver failure, which is accompanied by irreversible structural changes. You can not prescribe an antibiotic for porphyria ─ a genetic disease, a violation of the synthesis of hemoglobin in the liver, when the qualitative composition of the red cells changes.

    The antibiotic is not prescribed to patients with high sensitivity to tetracyclines, individual intolerance to doxycycline. As well as women with low leukocytes in the blood.

    Possible side effects

    While prescribing doxycycline for the treatment of cystitis in women, patients should be warned about the possible development of side effects:

    • on the part of the immune system ─ allergic reactions, rashes all over the body, rapid heartbeat, shortness of breath at rest, rarely ─ angioedema, anaphylactic shock, decrease in blood pressure,
    • on the part of the nervous system ─ pain in the temples and parietal zone, dizziness, decreased visual acuity, convulsions, general weakness, indisposition, drowsiness,
    • on the part of the psyche ─ an inexplicable feeling of anxiety, fear, confusion, depressive mood, hallucinations,
    • on the part of the digestive system: nausea, heartburn, single vomiting, dyspepsia, dry mouth, inflammation of the pancreas.

    According to the official instructions for use, the listed side effects occur only in case of violation of recommendations for reception, overdose.

    Antibiotic Uses

    Doxycycline capsules for cystitis in women are prescribed on an individual basis. Depending on the diagnosis, one course lasts a week on average, but does not exceed 10 days.

    In an acute attack of inflammation of the bladder, the first day is prescribed 2 capsules once or in the morning and evening, 1 capsule with an interval of 12 hours. Subsequent days drink 1 capsule per day.

    Chronic cystitis with frequent recurrences requires an increased dose. 200 mg is prescribed (2 drops) 1-2 times a day.

    Doxycycline irritates the mucous membrane of the esophagus and stomach, with prolonged treatment can provoke the development of ulcers and erosions. To prevent this, the drug is taken after meals. Instead of eating, you can drink a glass of milk or kefir, which does not affect the degree of absorption of the substance.

    The drug is washed down with plenty of liquid. It is better to use it in the morning. Use immediately before bedtime increases the risk of irritation of the gastrointestinal mucosa.

    During therapy, it is necessary to observe the exact dosage and the interval between doses of the antibiotic. For the effectiveness of treatment of cystitis, it is important that the concentration of the active substance in the blood is constant. Its reduction leads to the development of bacterial resistance. This situation requires the abolition of the drug and the appointment of more potent antimicrobial agents. If capsules are drunk more often, it will lead to an overdose and the manifestation of such negative consequences:

    • non-infectious kidney damage,
    • pancreatitis,
    • excess calcium in the blood.

    Doxycycline begins to act after 1.5 -2 hours after administration, when the concentration of a substance in the blood plasma reaches its maximum. The first days on the background of antibacterial therapy in a woman pass sharp pains, pain decreases during urination, the number of false urges to empty the bladder is reduced.

    The inflammatory process is quickly eliminated, signs of cystitis stop. During this period, the woman should not stop drinking the drug, so as not to provoke the re-development of cystitis. A noticeable improvement occurs in 3-4 days. It is necessary to complete the whole course of treatment, even if the symptoms of the disease have disappeared.

    Unidox as an available Doxycycline analog

    If, for certain circumstances, the patient cannot take medicine in the form of hard capsules, Unidox Solutab is prescribed for cystitis. The drug is an absolute analogue of doxycycline, but differs in the form of release.

    The antibiotic is made in the form of tablets, of which they independently prepare a suspension for oral administration (inside). They are biconvex, may differ in color, from yellow with a gray tinge to brown with splashes.

    Unidox for cystitis is prescribed in such cases:

    • bacterial infection (staphylococci, streptococci, gonococci),
    • inflammation of the bladder on the background of sexually transmitted diseases (urogenital mycoplasmosis, chlamydia),
    • cystitis, as a consequence of pyelonephritis (infectious inflammation of the renal pelvis), endometritis (inflammation of the inner lining of the uterus).

    Negative effects during treatment

    The list of side effects is extensive, similar to doxycycline. Since the antibiotic treatment of cystitis is short, women rarely complain of side effects from other organs and systems.

    In order to avoid unforeseen situations, patients are not recommended to drive a car during a therapeutic course. The antibiotic reduces concentration, slows down reactive abilities at the level of reflexes.

    The drug is prone to cause photosensitivity (sensitization) - an allergic reaction to ultraviolet rays. Therefore, for 3-4 weeks after treatment is forbidden to go to the solarium, sunbathe under the sun. This will lead to the appearance of age spots on the skin.

    Doxycycline reduces the effects of oral (hormonal) contraceptives. Therefore, while taking these drugs at the same time increases the risk of becoming pregnant.

    How to take Unidox

    Unidox Solutab with cystitis is taken orally as a suspension. To prepare it, take 1 tablet (100 mg), add 20 ml of pure water, stir until dissolved.

    The standard dosage for acute or acute chronic cystitis is 100 mg per day (for the first day, 200 mg can be prescribed as indicated). Severe, recurrent forms of inflammation of the bladder, with complications, require double dosage (200 ml) throughout the treatment.

    The antibiotic is taken 7 days, with streptococcal infection ─ 10 days.

    Interaction with other drugs

    The absorption of the substance slows down with the simultaneous use of antacid agents (for heartburn, in violation of the acidity of the stomach) ─ Almagel, Renny. If you can not cancel antacids, it is necessary to maximally divide the time of their reception with antibiotics.

    If patients are prescribed drugs of narcotic action (barbiturates), the dose of doxycycline should be increased, since psychotropic drugs accelerate the process of removing the active substance from the body.

    Alcohol affects the level of drug concentration in the blood.

    What is this medicine?

    This is a tetracycline drug, a broad-spectrum antibiotic. Doxycycline is active against most known pathogenic bacteria, both gram-positive and gram-negative.

    The drug is absorbed in the gastrointestinal tract almost in full, the effect of food on the absorption of the drug is not particularly significant. The average indicators of the degree of binding to the blood protein for this preparation are 80 = 95%. The half-life of the components of the drug - 18-22 hours. In some cases, the half-life is delayed up to a day, but this happens extremely rarely.

    The drug is removed from the body mostly with feces, up to 60% of the accepted amount of funds, less with urine. Metabolism for this drug is characteristic of the liver, and the antibiotic also affects the secretion of bile inside the human body.

    Forms of release

    It is available not only in the form of tablets, but also in the form of solutions for intramuscular injections and capsules, as well as concentrated lyophilisates for the preparation of solutions.

    Doxycycline is not only sold under this name, but also has trade names:

    Отличий между этими препаратами и упаковкой, на которой написано «Доксициклин» нет ни в чем.

    Показания при цистите

    The main indication for taking antibiotics in general and Doxycycline in particular in the treatment of cystitis is the presence of infection in the urethra or bladder. Taking this antibiotic is an effective way to quickly destroy almost all types of pathogenic bacteria, viruses, or microbes.

    That is, the use of drugs is advisable in the infectious nature of the disease, regardless of what form it takes.

    In addition to the initial presence of infectious agents in the urogenital system, which have become the causative agents of cystitis, the drug can also be recommended by doctors in the non-infectious nature of the disease. During the development of cystitis, the internal balance of flora is disturbed, which is the reason for the development of pathogenic microorganisms. This is especially common in women suffering from a chronic type of illness.

    Treatment with antibiotics, including Doxycycline, is also carried out with the development of secondary cystitis, which has arisen as a result of the presence of any infection in the body. For example, in men, cystitis often develops after an incompletely treated urogenital infectious disease, absolutely any, not necessarily venereal.

    The defeat of the body by fungi, for example, progressive thrush, is also the reason that antibiotics are used in therapy.

    Thus, the use of Doxycycline is advisable in almost any type of cystitis, including non-infectious chronic disease.

    It is also a very good drug Ampicillin. Read more.

    When and why not?

    Even in the case of the urgent need for the use of antibiotics in the treatment of the disease, doxycycline should be avoided:

    • in the treatment of children under the age of eight,
    • while carrying a child
    • during lactation.

    With regard to the state of pregnancy, it is strictly prohibited to use the drug in the II and III trimesters. Doxycycline therapy in the first trimester is permissible if absolutely necessary. This means that the use of the medicine is left to the discretion of the attending physicians, but only in the first part of the period of carrying the baby.

    The drug easily overcomes the placenta and enters the forming organism. Once inside, the medicine has a completely irreversible effect on:

    1. The color and condition of the bones, including the germinal elements of the teeth, their "bookmark".
    2. Suppresses the growth and development of the skeleton, makes the bones fragile, including the skull.
    3. It prevents the absorption of a number of nutrients and vitamins, necessary for full development.
    4. It provokes the development of fatty infiltration of the liver and other anatomical anomalies.

    For these reasons, in the second and final stages of childbearing with Doxycycline, it cannot be treated under any circumstances, however, as with other drugs belonging to the tetracycline group of medicines.

    The use of antibiotics in general during lactation is contraindicated due to the fact that they fall into the composition of breast milk. However, this contraindication is very relative. For example, in the event that cystitis is diagnosed in a newborn child, mothers who practice breastfeeding, on the contrary, are prescribed antibiotics.

    Thus, the treatment of babies. Children receive the medicine together with food in an adapted form and in a less aggressive form than when taken directly with water. Of course, it is impossible to do this without permission; it is necessary not only the approval of physicians, but also an individual calculation of the dosage, and the determination of the order of taking the drug.

    Children under eight years of age are not allowed to take the medicine because of the following nuances of its effect on the growing body:

    • color change of tooth enamel, irreversible,
    • enamel hypoplasia,
    • slowing the growth of the long bones of the skeleton,
    • abnormalities in the formation of muscle tissue.

    In some cases, the development of bone tissue marrow dystrophy is also possible. * years - conditional figure. Doctors prefer in practice to limit the treatment of children with tetracycline drugs to ten years of age.

    However, if there is no alternative to the drug, and the treatment is vital, the therapy is carried out. But only under the control of physicians and in individually calculated doses for taking the drug. The order of treatment in these situations is also determined by doctors.

    Other strict contraindications to the treatment of cystitis with this antibiotic are not available. The remaining contraindications are conditional and require caution in the use of medication.

    Is it possible with liver disease?

    According to reviews of those treated with this drug, if there are problems with the liver, the course of taking Doxycycline leads to a deterioration in the health of a person. Indeed, the dystrophy of the liver tissue, dysfunction, pathology and diseases of this organ are relative contraindications for the use of the medicine.

    In case of liver diseases or other pathologies related to the functioning and condition of this organ, the antibiotics of the tetracycline group should be taken with extreme caution and in the dosage calculated individually.

    Moreover, for liver ailments, the drug requires limiting insolation, at least 5 days before the start of treatment and another 5 days after completion of treatment. Insolation is the effect of ultraviolet on the human body, in any form.

    That is, you can not sunbathe, you are required to wear closed clothes, and it is also forbidden to visit the tanning bed and carry out any other procedures associated with ultraviolet rays. No need to visit nightclubs and other places in which ultraviolet light is involved in the lighting.

    Interaction with other medicines

    In the treatment of cystitis, regardless of their type and form of development, not one drug is used, but a complex of drugs. Of course, this raises questions about their compatibility.

    Of course, doctors do not prescribe medications that are incompatible with each other, but pharmacies may not have prescribed medication, but its counterparts are present. To consult with doctors about replacing one remedy with another, there is no means always.

    Often, side effects or low effectiveness of treatment of cystitis are not formed due to the joint use of Doxycycline with other medicines, but due to the use of dietary supplements and vitamin complexes, the composition of which prevents the absorption and action of the tetracycline antibiotic.

    The medicine is incompatible with any medication or other means containing:

    1. Iron.
    2. Aluminum.
    3. Magnesium.
    4. Calcium.
    5. Barbiturates.
    6. Carbamazepine.
    7. Phenytoin.
    8. Sodium bicarbonate.
    9. Kolestiramine.
    10. Colestipol.

    The effectiveness of the antibiotic decreases with the use of food containing these components. For example, by eating cottage cheese, milk or sour cream, the active ingredient of the drug is absorbed only by 10%. Strawberries, currants, strawberries, apples reduce the absorption of the drug to 5%.

    When eating foods that adversely affect the absorption of an antibiotic, taking the medication is advisable either three hours before meals, or 3-4 hours after it.

    Particular attention should be shown to people accustomed to drinking herbal teas. Healing herbs are strong biologically active natural remedies and contain many trace elements that are not always compatible with antibiotic treatment. Moreover, all plants have the ability to accumulate in the body.

    That is, if a person drinks tea from lime blossom with strawberry leaf and carcade for a long time, for example, or uses pomegranate juice daily, you should stop drinking them no less than a month before using the tetracycline antibiotics.

    Simultaneous use of doxycycline and contraceptives can also cause a low efficacy of therapy or a complete lack of results. Most hormonal contraceptives contain components that are incompatible with the action of the tetracycline antibiotics.

    Accordingly, when using such methods of contraception, before starting treatment it is necessary to carefully study the composition of contraceptives and consult with your doctor about the time of removal of their components from the body. It is likely that treatment options for cystitis will have to be reviewed or delayed initiation of therapy.

    There is another important feature. The simultaneous use of tetracycline antibiotics, including doxycycline, with vitamin “A” in oil or gelatin balls, as well as with products containing retinol in large quantities, leads to an increase in intracranial pressure.

    It is especially important to remember this for older people, since they are more difficult to tolerate pressure drops than middle-aged people, young people or children. Of course, in no case should food be combined with vitamin A content, any pharmaceutical complexes, dietary supplements or teas with retinol for people prone to stroke or migraines, as well as for those who initially suffer from increased intracranial pressure.

    Treatment regimen

    The main rule in taking drugs of the tetracycline group is the same time of their direct use. This means that the time taken to take pills or capsules should be the same throughout the entire course of treatment.

    The maximum permissible and safe dosage of the drug is 300 mg per day. The only exceptions are cases in which cystitis is caused by staphylococcal or gonococcal infections. With such diseases, the dosage is doubled, conducting a kind of "shock therapy", in the absence of contraindications, of course, and with good tolerance to the components of drugs of the tetracycline group.

    The treatment for cystitis caused by staphylococcal or gonococcal infections is as follows: