Man's health

Finast: reviews of men, price, instructions for use

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Prostate adenoma is a proliferation of a benign prostate. This condition is on the verge of physiological and pathological, since it manifests itself in almost all men of old age and is considered a kind of sign of aging of the organ. But at the same time, it causes a huge number of unpleasant symptoms, and therefore requires treatment.

To get rid of this pathology, two methods of treatment are used - conservative and operative. If the prostate gland has grown slightly, and the disease is in its early stages, then resort to drug, that is, conservative, therapy.

Finasteride has proven to be an excellent drug for prostate adenoma. But you can't just drink it, you should carefully study the instructions for use and consult with your doctor before use. Since the drug is not for everyone.

What are the symptoms of Finasteride?

Before the appointment of treatment, it is necessary to undergo examinations that will help to find the disease. But the following subjective sensations should be the reason for turning to specialists:

  • the duration of urination increased significantly,
  • urine pressure noticeably weakened, jet sluggish, can sometimes be interrupted,
  • after going to the toilet there is no feeling of emptying the bladder,
  • at the very beginning of urination, there is a delay between muscle relaxation and the appearance of a jet,
  • at the end of urination, urine may begin to stand out in droplets,
  • at night you have to frequent the toilet,
  • trips to the toilet also increased in the afternoon,
  • in some cases you have to strain yourself to urinate,
  • incontinence incidents are sometimes possible.

All these signs may indicate prostate adenoma. In order not to start the process, treatment should begin at the first symptoms.

Finasteride Composition

The main active ingredient has the same name as the commercial name of the drug - finasteride. Usually one tablet contains 5 mg.

But, in addition to this component, there are also adjuvants:

  • lactose monohydrates,
  • cellulose and starch,
  • titanium dioxide,
  • magnesium stearate.

They all give a specific shape and type of tablet, and also do not give it too early to dissolve. They help deliver Finasteride exactly where it should begin to absorb and act.

The drug is prescribed to stop the proliferation of glandular tissue, as well as reduce prostate hyperplasia. It helps to restore the patency of the urethra, improve the flow of urine through it, as well as reduce the brightness of clinical manifestations. In addition, it significantly reduces the risk of acute urinary retention, which may require surgery.

When you can not drink the drug

Finasteride is strictly forbidden to take women, and during the carrying of the child is undesirable, in general, any contact with the drug. This is due to the fact that the active ingredient of this drug has a negative effect on the fetus, especially male. It interferes with the normal development of the genital organs in the embryo.

Also, do not use the drug for people who have a history of allergic reactions to any components of Finasteride. The experience of using this drug for the treatment of diseases in children do not have, so they are also contraindicated intake.

How to drink the drug

Take Finasteride should be 1 tablet once a day. It is not recommended to exceed the daily dose of 5 mg, because the drug contains hormonal substances. And this should not be abused.

The course of treatment is always very long. It can be from 5-6 months or more. But all these criteria should limit the doctor. The drug should be administered under the constant supervision of the attending physician with regular testing.

Side effects

Like any other, and especially hormonal preparations, Finasteride has not only a positive side - a healing effect, but also a negative one - adverse reactions. They can arise from various organs and systems:

  • immunity - allergies, angioedema on the lips and face,
  • epidermis - various types of rash on the skin, severe itching, sometimes - urticaria,
  • digestive organs - increasing the concentration of liver samples,
  • cardiovascular disorders - palpitia, that is, trembling of the heart muscle, in rare cases - tachycardia,
  • psyche - a sharp decrease in libido (craving for the opposite sex). Usually, this unpleasant moment occurs at the beginning of therapy and disappears completely by about the end of the second week of treatment. In rare cases, low libido can be observed during the entire course, as well as persist after discontinuation of the drug. Another mental disorder can be a depressive state,
  • genitals - transient impotence, pain in the scrotum, impaired sperm release (ejaculation), decreased sperm concentration and motility in sperm,
  • soreness, swelling, sometimes a significant increase in the mammary glands in men.

If you experience such unpleasant symptoms, you should inform your doctor. Since it may be necessary to adjust the dose of Finasteride or the selection of any analogue.

Reception features

Patients who take Finasteride increase the risk of obstructive uropathy. This is a condition during which the obstruction of the urinary tract is violated in any part of the entire system. It is dangerous in that it can lead to kidney pathologies and impairment of their functions.

Before you start taking Finasteride, you should make sure that the following diseases are absent in the body, which are easily confused with prostate hyperplasia:

  • oncological process in the prostate gland,
  • bladder muscle weakness
  • prostatitis,
  • urethra stricture,
  • violation of innervation of the bladder.

Opinion of patients

Reviews of Finasteride for prostate adenoma in men are very different. Some people write that taking the drug did not help them at all, and sometimes even made it worse, because it caused side effects. Still, most of the reviews are positive.

People say that the medicine helped them to get rid of the problem, removed the unpleasant symptoms and did not cause any negative changes in the body and well-being. Also, patients note that the pricing policy of Finasteride is very loyal, so even long-term use of the drug does not have a strong budget. Below are some reviews.

Pharmacodynamics

The essence of the action of finasteride is to suppress the activity of the enzyme 5-alpha reductase. This leads to the prevention of the transformation of testosterone into the active androgenic hormone 5-dihydrotesterone. The concentration of this androgen decreases both in the blood and in the prostate gland itself, which prevents the growth of gland tissue.

As a result of treatment, the prostate gland is reduced in size, and the symptoms of the disease become less pronounced.

Pharmacokinetics

Finasteride is very rapidly absorbed in the digestive system. Moreover, its bioavailability is 80%.

The maximum concentration of the drug in the blood will be reached in 1-2 hours after the medicine has been taken. Finasteride binds well to plasma proteins - up to 90%.

Drug metabolism occurs in the liver, and the metabolite is excreted in feces and urine.

Indications for use

The drug is prescribed for prostate adenomawhen necessary:

  • reduce the size of the gland when benign hyperplasia,
  • increase urine flow rate,
  • reduce the symptoms of hyperplasia,
  • reduce the risk of the need for urgent surgical intervention due to acute urinary retention.

Side effects

During drug treatment, the following side effects may occur:

  • allergic reactions to the components of the drug,
  • gynecomastia,
  • decrease or absence of sexual desire,
  • reducing the amount of ejaculate in volume
  • a slight increase in levels of LTG, FSH, testosterone, but not above the upper limit of normal.

Side effects during the treatment period occur in only 3-4% and usually go away after a while with continued therapy.

special instructions

Before you begin treatment, you need to conduct examinations that will help make sure that the patient has a benign hyperplasia, and not other diseases that give similar symptoms. And during drug therapy, periodically you need to conduct a study in order to exclude prostate cancer.

It is necessary to take very carefully Finast patients who have problems with the functioning of the liver.

It is forbidden to drink tablets Finast and even contact with them to all women of childbearing age, especially during pregnancy. This is due to the fact that the active substance can disrupt the formation of genital organs in boys in the period of embryonic development.

Composition and release form

The drug is available in tablet form. Tablets have a special coating that facilitates the delivery of the active substance to its destination. It protects Finasteride from the external effects of enzymes.

The composition of one tablet contains 5 mg of active substance. It is not the only component of the drug, because it also contains auxiliary substances. Among them:

  • sodium lauryl sulfate,
  • cellulose,
  • titanium dioxide,
  • starch,
  • lactose and others.

Full list of substances listed in the instructions for use. It should be familiar with people who are prone to allergic reactions.

Finasteride tablets are blue and engraved with the inscription "FNT 5". On the cross-section, one can observe a white core, in which the active substance is contained.

Mechanism of action

Finasteride is a synthetic hormone that affects the 5-alpha reductase enzyme found in the prostate gland. With it, testosterone, which is secreted by the testes, turns into a more active form - dihydrotestosterone.

Often, benign prostatic hyperplasia, in which Finasteride is indicated, is due to the excessive conversion of the male androgen into its active metabolite. By reducing the amount of the latter in the plasma and tissues of the prostate, the drug helps to normalize the size of this organ.

The medicine begins to act within half an hour after ingestion. The maximum concentration of its active component in the blood is observed 2 hours after taking the pill.

Prostate tissue reaches 80% of the active substance. The absorption of the drug does not depend on food intake. In the blood, Finasteride is almost completely bound to proteins, with which it is transported to the site of direct action.

The drug has the ability to slowly accumulate in the body. Prolonged therapy leads to the fact that the substance is detected in the semen, cerebrospinal fluid. This is not a pathology.

Displays the agent through the intestines and kidneys in a modified form. The half-life is from 6 to 8 hours. In older people, Finasteride is more slowly excreted, but this does not affect the dose of the drug.

Does not affect the removal of chronic renal failure. With her, most of the active substance is excreted through the intestines. Only the need for hemodialysis in a patient can affect the amount of medication taken.

Regimen

The drug is taken under the supervision of a doctor who decides whether to continue treatment.

Finasteride is taken orally once a day. The standard dosage is one tablet containing 5 mg of the active substance.

Conduct both monotherapy and combination therapy with this drug. In the latter case, it is taken along with Doxazosin.

Analogues of Finasteride differ only in their trade name. The active substance contain the same, but before they are taken it is necessary to consult with a specialist. Pharmacies can meet funds under the following names:

  • Prosterid
  • Finast,
  • Alfinale,
  • Urofin,
  • Penester
  • Zerlon and others.

The features of the course depend on the stage of the pathological process in the prostate gland and the individual susceptibility of the organism to treatment. Often, doctors resort to pulsterapii, a method that involves alternating methods of rest and means. After 6 months of treatment, the drug is canceled for 3 months, after which the course is repeated. This is done to consolidate the effect and prevent withdrawal.

Contraindications

There are the following contraindications to the use of Finasteride:

  1. Allergy to the active substance or any component that is part of the drug.
  2. Malabsorption syndrome, interfering with the normal absorption of the drug.
  3. The intolerance of the lactose which is a part of tablets.
  4. Age up to 18 years.
  5. Obstructive disorders of urine outflow.

Before taking especially careful should be people who have a large amount of residual urine. It is undesirable to take Finasteride in patients with liver failure. The latter is due to the fact that the liver is the main source of proteins that bind the active substance and transport it to the prostate. Their lack leads to a decrease in the effective concentration of the drug in the blood and tissues, which prevents the therapeutic effect of the drug.

Before starting a course of therapy, patients should make sure that they have no prostate cancer and bladder innervation disorders. Contraindications to the start of treatment is an infection of the prostate gland.

Pregnant women should avoid taking Finasteride by accident, which has a teratogenic effect. The substance is especially dangerous for male fetuses, since it violates the intrauterine development of their genitals.

Drug price

The price of funds depends on the manufacturer, as well as the place of purchase. A package of 30 tablets of 5 mg costs about 230–350 rubles.

Domestic counterparts are cheaper, although there are no studies proving their lower effectiveness in comparison with foreign funds. The latter are traditionally perceived as being of higher quality, but before buying a drug of a company, it is better to consult a practicing physician.

Reviews about the use of the drug in the treatment of prostate adenoma vary greatly. Some men write about their experiences using this drug.

Ivan, 50, Ufa:

“Finasteride had no effect in the treatment of adenoma. After 4 months of the course, he quit taking the drug, as he did not feel any visible improvement, although it did not get any worse. ”

Artem, 36, Moscow:

“I took it on the advice of a urologist. The pills helped to cope with urination problems. On ultrasound, the doctor recorded a decrease in the prostate after 6 months of administration. I was afraid of the side effects described in the instructions, but in fact I did not encounter them. ”

Andrei, 43, Perm:

“The drug has helped. After the first two months, I thought about stopping taking it, but I continued to drink and felt the effect. Now urination problems don't bother me anymore. ”

According to some reviews, patients often discontinue finasteride on their own. In such cases, one should not hope for a positive effect, because a violation of medical recommendations leads to a lack of effect from therapy.

Starting to take the drug, be sure to follow all the advice of the doctor. The decision to cancel treatment can only be made by a doctor based on the results of tests or data of objective examination.

Description of the pharmacological action

Finasteride is a competitive and specific inhibitor of steroid 5-alpha reductase - an intracellular enzyme that converts testosterone into the active androgen 5-dihydrotestosterone (DHT). By blocking 5-alpha reductase, finasteride prevents this transformation, thereby preventing the growth of prostate tissue and the development of benign hyperplasia. Reduces the concentration of DHT in plasma and gland tissue. It does not bind to androgen receptors. It reduces the size of the prostate gland and the severity of symptoms associated with prostate adenoma. The drug does not affect plasma lipids or plasma cortisol, estradiol, prolactin, TSH, thyroxine.

Release form

tablets, coated 5 mg, strip 10, pack cardboard 3, Composition Tablets, coated 1 tablet finasteride 5 mg adjuvants: lactose, MCC, carboxymethyl starch sodium (type A), corn starch, pregelatinized, sodium dokuzat, magnesium stearate, hygroelloid , titanium dioxide, talc in a strip of 10 pcs., in a pack of cardboard 3 strips.

Admission precautions

Before treatment, it is necessary to exclude diseases simulating benign prostatic hyperplasia (infectious prostatitis, prostate cancer, urethral stricture, hypotonic bladder and changes in the urinary system arising from certain diseases of the nervous system). With caution prescribed to patients with impaired liver function. Periodically, in the course of therapy, it is necessary to conduct an examination of patients in order to exclude prostate cancer in them (because when using finas erida a decrease in prostate-specific antigen - on 41 and 48%, respectively at 6 and 12 months from the beginning of therapy) .Zhenschinam of childbearing age and pregnant women should avoid contact with crushed tablets of the drug due to possible violations of the sexual organs in male embryos.

Causes of baldness

There may be a lot of them. Hair can fall out due to the lack of certain vitamins and minerals, severe stress. Serious diseases and the use of potent drugs, alcohol abuse and smoking - all this adversely affects the health and beauty of your hair. But today we are talking about focal prolapse, when a bald patch is formed at the place of the luxurious head of hair. The reason for such metamorphosis often lies in the change in hormonal levels. It is for the treatment of such conditions that the drug "Finasteride" is used. Reviews of men say about the high effectiveness of this tool. But it is necessary to warn those who want to solve hair problems with the help of this drug: it can be used only as prescribed by a doctor, because it is a hormonal remedy.

Women are especially sensitive to their hair, but we hasten to warn you: this problem does not solve many problems that contribute to hair loss in the fair sex.

pharmachologic effect

Today we are considering the drug "Finasteride". Men’s reviews can confuse the reader a little, as they mainly concern the treatment of prostatic hyperplasia. This is not surprising, if you look at the market for the treatment of baldness in general. All of them were originally made with completely different goals, but in the course of research, scientists discovered such a side effect as improving hair growth. The first drug, which at the time of the study was recognized as a cure for baldness, was "Finasteride". Reviews of men rightly point to a steady, though not too fast, effect. On average, researchers call the figure 12 months. This is the period in which healthy hair will appear.

Medicine for treating baldness and prostate gland

Today, the most famous anti-baldness drug is Finasteride. For hair it is really amazingly effective, provided that the reason for their loss lies in the area of ​​hormonal imbalance. The first country to recognize the drug as the No. 1 drug in the fight against androgenic alopecia is the United States. Additional research and clinical trials have been conducted here. During their conduct, the scope of the drug has expanded from the treatment of an enlarged prostate gland in men to purely cosmetic problems. Clinical studies have shown how effective "Finasteride" is for hair. Its use provokes their growth on the head and changes in the state of hair. The hairs themselves become stronger and tougher. After the course of treatment, it is necessary to carry out maintenance therapy in order to maintain the achieved result.

Finasteride is gaining popularity

Around 1977, Finasteride was actively used in the United States and then in Europe. Analogs began to appear much later, just below we devote time to them. At the same time, the stable interrelation of disturbances in the work of the prostate gland and the problem of baldness was emphasized more than once. The drug allows you to solve both problems simultaneously, assists in the treatment of benign prostatic hyperplasia, can reduce the size of the enlarged gland, improve the flow of urine and reduce the risk of its acute delay.

But even more often use the drug "Finasteride" for baldness. Reviews, analyzed by dozens of doctors, allow us to say that people who have taken it during the year achieve their goal. At the same time, experts draw your attention to the fact that if after 12 months the hair does not begin to recover, it does not make much sense to continue taking the drug. It is necessary to be examined again and to correct the direction of therapy. But at the same time it should be noted that the results are impressive. In 90% of men treated with Finasteride, the loss stopped and hair began to grow.

During the period of therapy, the number of bald patches significantly decreases or they disappear completely. At the same time, the drug "Finasteride" has a very positive effect on the structure of the hair. They become smoother and more beautiful.

Little about therapy

Fast results with this tool can not be achieved. The course of treatment of the prostate gland usually takes from 5 months, while the problem of baldness can persist much longer. In some cases, it is recommended to take the drug for several years. The tool is most often prescribed in pill form and taken orally. There is also "Finasteride" - lotion, reviews of which are also quite good. Apply it too on the scalp, about 1 ml (6-8 presses) twice a day. The drug is easily absorbed and penetrates the tissues and fluids of the body. The drug has a high level of bioavailability. It begins to act almost instantly, reaching maximum impact approximately two hours after application. Decomposition products are excreted by the kidneys and liver, while metabolites do not affect the work of the organs themselves.

It is considered that visible improvements will begin to appear approximately 3-4 months after the start of treatment, but for the result to be stable, it is necessary to apply the remedy from six months to several years, at the discretion of the attending physician. In this case, the dosage should also be prescribed by a doctor, under careful control, it can significantly increase for a certain period.

Patient's state of mind during therapy.

Finasteride is not always 100% well tolerated. Instruction, reviews of former and current patients warn of such changes as weakening of the libido. That is, a healthy man may have a natural craving for the opposite sex, signs of impotence and weakening of sexual desire will appear. This is a natural reaction of the body to treatment with hormonal drugs, at the end of the course the state will slowly return to normal.

Is this remedy for men only?

Why is the product focused on men and can Finasteride be used for women? Reviews suggest that in the fight for long and beautiful hair of the fair sex more than once tried to find salvation in this new drug. However, initially it is not focused on women. Only if the doctor, after examining and examining your endocrine system, diagnoses male-pattern baldness, will its use be justified. Most often, baldness in women has other reasons, so you can not take the drug yourself. It is especially dangerous during pregnancy, as it causes serious malformations of the fetus. In any case, you can not self-medicate and use "Finasteride" for women. Reviews do not contain any evidence of the effectiveness of such therapy, but health problems can be gained quite a lot.

Health status and duration of therapy

In no case should the drug be administered to children. Any hormone therapy for babies is dangerous. In addition, the physician must determine the safe duration of therapy for each individual patient. To do this, he needs to collect information about the age and illness of the patient, operations. It is very important to learn as much as possible about what drugs a person takes. Any of them can worsen or slow down the effectiveness of therapy with Finasteride. Analogs of this drug act in the same way, which means that they need to approach the question of their purpose with no less responsibility.

There are a lot of generics on the market today. These are drugs created on the basis of clinical studies that were conducted during the development of the original drug. That is why they differ greatly in price, that is, are more profitable, but no less effective. One of the most popular is the generic "Propecia". This is a drug for the treatment of the hereditary form of baldness in men. Externally, it is a pathological hair loss in the frontal and parietal lobes. The reason for this is quite specific - the high content of the active form of testosterone in the blood. This leads to malnutrition, thinning and subsequent hair loss. Other analogues of the drug are Alfinale, Penester, Proscar, Prosterid.

How long does the effect last

Indeed, the feedback from men who took Finasteride-Teva mostly reflects good results. Regardless of the area of ​​baldness, gradually begins to grow a new hair. Accordingly, the question arises as to how long this effect will be. Unfortunately, a complete cure of the drug can be given only if baldness is directly related to impaired function of the prostate gland. Then both problems are solved simultaneously.

If hair loss is a consequence of androgenic alopecia, that is, it has a genetic susceptibility to elevated levels of testosterone in the blood, then treatment will only give a temporary effect. After discontinuation of the drug, the hair will begin to fall out again. The physician may prescribe a maintenance dosage that must be taken continuously.

Let's sum up

If you are faced with a balding problem, then know that there is a solution. But at the same time, it is impossible to start taking the drugs yourself, there are professionals who, after conducting an examination, will prescribe you the most suitable treatment. By following all the recommendations of the doctors, you can avoid most of the side effects and achieve excellent results.

Composition and dosage forms

The manufacturer manufactures the drug in pill form. As the active substance of the drug used finasteride hydrochloride (5 mg per tablet for oral administration). Additional ingredients:

  • sodium carboxymethyl starch,
  • pregelatinized corn starch,
  • magnesium stearate,
  • sodium dokuzat,
  • propylene glycol,
  • hypromellose,
  • MCC
  • titanium dioxide,
  • dichloromethane,
  • purified talc,
  • lactose.

Finast was developed specifically to solve problems such as prostate adenoma (hyperplasia).

The tablets are packaged in packs of 30 pcs.

In old age

Specific selection of daily doses is not required. Clinical trials have shown that the T1 / 2 of the active substance slows down in this category of patients.

Terms and conditions of storage

Store in a dark place inaccessible to moisture at room temperature. Properties of the drug are stored for 24 months after manufacture.

Similar properties have such drugs:

Men reviews

Petr Korolev, 46 years old, Novomichurinsk

I'm already tired of the constant exacerbations and inflammation of the adenoma. Under the surgical scalpel I have not yet decided to lie down, the doctor advised me to complete a full course of hormonal treatment for a period of 6 months and wrote out these pills. Already I finish taking them, my condition has improved - my urine has improved, at night I don’t go to the toilet anymore, the pain and pain have disappeared, my mood has risen. In the first weeks, mild discomfort appeared in the chest and scrotum, but the discomfort soon passed away. Good drug, now I will recommend it to all my friends.

Vladimir Mitin, 44, Moscow

I was diagnosed with prostate hyperplasia accidentally when I was undergoing a routine medical examination in the direction of the employer. I was surprised, because I did not experience any problems. The doctor prescribed this hormonal drug. I was cautious about the medication because I studied the reviews on the Internet and saw many side effects among them. Gathered with strength and thoughts, began to take. I use pills for the third month. There were no complications due to them, even the potency increased.

Anton Korpatov, 53, Shilovo

I have prostatitis. I use the drug as directed by the urologist to normalize the urinary process. I observe the reception schedule appointed by the specialist, I never missed it. There is still discomfort when going to the toilet, but the intensity has become lower. The doctor said that the positive effect of taking this drug is gained gradually.

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