Thyroid

What is the use of Dexamethasone with Eufillin?

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The drug "Eufillin", reviews of which are very diverse, is a bronchodilator drug. This drug belongs to the group of xanthines. It can be purchased at almost any pharmacy, but it is desirable to use such a drug for therapeutic purposes only as directed by the doctor.

Forms of release and composition of the drug

Currently, the drug can be purchased in two different forms, namely:

  • In tablets that contain 150 mg of an active ingredient such as aminophylline. In the sale of this drug comes in carton 50, 10, 30 or 20 pieces.
  • The drug "Eufillin" in ampoules. 2.4% solution for injection (1 ml) contains 24 mg of aminophylline.

On what form of the drug to use for the treatment of a disease, you should recommend only the attending physician.

Drug properties

As mentioned above, the drug "Eufillin" in ampoules or tablets contains the main substance - aminophylline. In turn, this component is a mixture that consists of 80% theophylline and 20% ethylenediamine. This composition greatly facilitates the solubility of the drug, and also significantly improves its absorption.

The drug "Eufillin" from what is prescribed by doctors? The evidence of this tool is due to its effect on the bronchi. Thus, the drug "Eufillin" is able to relax the smooth muscle tissue of the above-mentioned organ and eliminate spasms arising in them. It rather effectively improves the functioning of the epithelial cilia of the respiratory tract, and also increases the contraction of the intercostal, diaphragmatic and other muscle tissues.

What is the feature of the drug "Eufillin"? Patient reviews state that this medicine is capable of stimulating the respiratory center in the medulla, as well as improving pulmonary ventilation, oxygenating the blood and reducing carbon dioxide content in it, that is, normalizing respiratory functions.

The principle of the drug

The mechanism of action of the presented agent lies in the fact that it inhibits the enzyme phosphodiesterase, due to which cyclic adenosine monophosphate accumulates in the tissues, and the influx of calcium ions into the cells responsible for muscle contraction is reduced, which relaxes the smooth muscles of the bronchi.

It should also be noted that the drug "Eufillin" (ampoules, tablets) is able to stimulate heart activity, due to the increased frequency and strength of myocardial contraction. It lowers the tone of the blood vessels of organs such as the kidneys, brain and skin.

Providing a relaxing effect on the walls of the veins in the pulmonary circulation, this medication helps reduce the pressure in it. The use of the drug "Eufillin" significantly improves the blood supply to the kidneys. Due to this, the formation and, accordingly, the excretion of urine significantly increases. The tool helps to slow down platelet aggregation. We can not say that "Eufillin" makes red blood cells resistant to damage. In other words, it significantly improves the rheological properties of blood.

It is also known about the tocolytic effect of this drug on the uterus. It can also increase the acidity of gastric juice.

Suction and excretion

The drug "Eufillin" - from what it is used by patients? Before answering the question, it should be said that this medicine is quite well absorbed from the digestive system. Its bioavailability reaches almost 100%, although with simultaneous intake with food, the absorption of the drug may slow down markedly.

This medicine penetrates the milk of a nursing mother and does not stop in front of the placental barrier. Metabolism means occurs exclusively in the liver. Its excretion from the human body through the kidneys.

The drug "Eufillin": indications for use

The drug “Eufillin” is prescribed for obstructive chronic bronchitis, for relieving attacks of asthma (in patients with physical stress asthma and as an additional remedy for other forms), for asthmatic status (only in combination therapy), heart failure, complex treatment of stroke, also other ischemic conditions of the brain, angina pectoris, Cheyne-Stokes respiration, pulmonary emphysema, pulmonary edema, and other abnormalities that are associated with congestion. According to patients, the drug "Eufillin" (solution for intravenous injection and tablets) effectively lowers the pressure during a hypertensive crisis. It is often used to treat apnea in newborns, that is, in a condition that is characterized by periodic cessation of breathing (for 15 seconds), and is accompanied by such deviations as bradycardia and cyanosis.

Contraindications to use

The drug "Eufillin" (indications for use of this drug include many exceptions) has a large number of contraindications.

So, the presented medicine is not recommended for treatment, if you have at least one of the following phenomena:

  • hypersensitivity to one of the component substances, including derivatives of such an element as xanthine (pentoxifylline, caffeine, theobromine),
  • arterial hypertension,
  • arrhythmia,
  • myocardial infarction,
  • myocardial pathology,
  • heart failure,
  • duodenal ulcer or stomach ulcer
  • chronic or acute (especially in the acute phase) gastritis,
  • diarrhea,
  • prostate adenoma,
  • pulmonary heart,
  • cystic fibrous mastopathy,
  • hypoxemia
  • alcoholism,
  • hyperthyroidism
  • fever,
  • diseases of the rectum,
  • respiratory tract infections
  • disruption of the liver,
  • acute or chronic kidney failure,
  • edematous syndrome,
  • breast-feeding,
  • hypernatremia,
  • pregnancy.

Instructions for use

In the form of a solution, such an agent is administered intramuscularly or intravenously. It should be noted that parenteral use of this drug is used only in emergency and emergency conditions. In this case, the dosage of the drug must be calculated individually and depend on the rate of excretion in different people, the severity of the patient’s condition and the weight of his body.

What rules should I know to inject intravenously drug "Eufillin"? The medicine dropper should be placed very carefully, and most importantly - slowly.

According to the instructions, for adults in emergency situations, the dosage of this drug is selected at the rate of 6 mg per 1 kg of weight. To do this, the drug must be diluted in 20 ml of physiological solution "sodium chloride" and the drug is administered intravenously. The injection is carried out very slowly (over 5-8 minutes).

If a patient has asthmatic status, then he is assigned to the infusion of the drug in the amount of 720 or 750 mg. The duration of such therapy should not exceed 14 days.

In order to alleviate the patient's condition in obstructive pulmonary diseases (especially in the acute phase), the administration of the drug begins with a dosage of 5 or 6 mg per 1 kg of patient weight. If necessary, it can be increased. However, this should be done very carefully, controlling the blood picture.

As for the pills, in this form of "Eufillin" prescribed to 0.15 g after a meal once or three times a day. The course of treatment may last several days or months.

When neonatal apnea, the initial dosage of this tool is 5 mg per 1 kg of body weight per day (in 2 doses). In this case, the drug is administered by nasogastric tube. After improving the condition, switch to maintenance therapy (2 mg per 1 kg per day in 2 divided doses). The duration of treatment of a disease can be several weeks or months.

Children younger and older drug is prescribed depending on the evidence and the severity of the condition. The daily dosage varies in the range of 6-15 mg per 1 kg of weight.

Inhalation "Eufillin"

The drug is indispensable for obstructive bronchitis. This is due to the fact that it facilitates the removal of sputum and well dilates the blood vessels of the bronchi. In physiotherapy rooms, which are located in each clinic, inhalation procedures are carried out on the basis of a large amount of this tool. So, for 3 ampoules of medication you need to use 10 ampoules of "Dimedrol", as well as 500 ml of water. If a conventional compressor nebulizer is used for treatment, this dosage will be much lower, although the proportions should be maintained.

Before you breed and use "Eufillin" for inhalation of the baby, you should always consult with the pediatrician.

Possible side effects

According to reviews, the drug "Eufillin" can cause such undesirable phenomena as dizziness, insomnia, excessive agitation, constant headaches, arrhythmia, tremor of extremities, lowering blood pressure, abdominal pain, heart palpitations, nausea, heart pain, heartburn, allergic reactions, vomiting, diarrhea, lowering of glucose in the blood, increased sweating, changes in urine tests.

special instructions

When should I take Eufillin with extreme caution? Reviews of experts indicate that this drug should be used only on prescription and strictly under his supervision, especially if the patient has a fever of unknown origin. With extreme caution should take the drug to the elderly.

It should be noted that the drug "Eufillin" can increase the level of uric acid in the urine. During the use of this medication, you must take special care while consuming large amounts of foods and drinks containing caffeine.

Before parenteral administration, the drug solution is recommended to be heated to body temperature.

Treatment of osteochondrosis with Dexamethasone

With mild indicators of exacerbation of this disease, anti-inflammatory drugs are more often recommended for oral administration (tablets). In cases of pain in the cervical regions caused by intervertebral hernia, injections are given with an anesthetic drug.

The use of Dexamethasone with Euphyllin helps to effectively eliminate severe pain in situations where nonsteroidal drugs are not able to have a full effect on pain in the spine. However, in Russian medicine, non-hormonal anti-inflammatory drugs are still preferred. Drops "Eufillin with Dexamethasone," doctors prescribe in extreme cases when it is necessary to neutralize the ability of Dexamethasone to provoke vasoconstriction.

When used Eufillin

Euphyllinum belongs to the group of bronchodilators and is prescribed mainly for asthma. It allows to stop various aggravations in vessels of atherosclerotic nature. Used in combination therapy for circulatory failure of the brain to reduce intracranial pressure and the occurrence of its edema. Euphyllinum improves blood circulation, has an analgesic effect and relieves muscle spasms.

However, it has a number of side effects and its contraindications: dropper Eufillin with Dexamethasone or another medicine is not suitable for the treatment of osteochondrosis for people suffering from:

  • cardiopathology,
  • severe hypertension or hypotension,
  • any form of epilepsy,
  • severe pathologies of the liver or kidneys,
  • intolerance to the drug.

When a drip is needed

Intravenous administration of Dexamethasone, mixtures of Dexamethasone, Eufillin and Novocain or Dexamethasone, Eufillin and Sodium Chloride is necessary in order to maintain the required concentration of the active substance. This allows you to achieve a certain therapeutic effect.

Dexamethasone and Eufillin in osteochondrosis is used in cases of extreme necessity with a sharp exacerbation and severe pain syndrome. Judging by the reviews, this technique is more effective for rapid relief of aggravation.

Radiculitic mixture

In the treatment of diseases of the musculoskeletal system, including osteochondrosis, often use combinations of drugs. The use of Dexamethasone with Euphyllin is often supplemented by analgesic and dehydrating drugs. One of the recipes of these cocktails, effectively used for the relief of acute pain during exacerbation of the disease, has the following description:

Prepare a mixture of 150 ml of saline and Eufillin, Dexamethasone, Baralgin (or Analgin), Lasix, taken in 1 ampoule for injection. The mixture of drugs Baralgin, Dexamethasone, Eufillin and Sodium Chloride is administered intravenously. Since Lasix is ​​a diuretic, it is added to the medicinal cocktail through the gum dropper at the end of the jet procedure.

The course of treatment is usually 3-5 droppers of such a cocktail daily or every other day. The indication for use is the exacerbation of osteochandrotic manifestations in various parts of the spine, accompanied by severe pain. However, all drugs included in the mixture have their own contraindications, so this drug cocktail should be prescribed by a doctor.

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The essence of the procedure

Many people mistakenly believe that the drip of the drug is prescribed in patients with a serious condition. In fact, the use of infusions due to special indications. What is a dropper?

The dropper set for emergency care.

This is a plastic tube, in the middle of which there is a small reservoir for solution, and at the ends there are two needles. One of them is inserted into the vial with the drug, and the second is injected into the vein. The dropper is equipped with a pipette through which the drug drip enters the end of the tube directed to the vein. The procedure provider can monitor the speed of the medication and regulate it using a special device that squeezes the upper part of the tube from the outside.
When adjusting the dropper, it is necessary to create a certain level of liquid medication in the lower part of the reservoir to prevent air from entering it, which can then penetrate into the vein.
Another long air inlet needle is inserted into the vial: without it, the drug cannot get into the tube. Another important point is the need to locate the reservoir above the level of the vein into which the solution will be injected. For this reason, the dropper is suspended on a special rack.

In what cases prescribed drip drug

With the usual administration, many medicines quickly disintegrate in the body or are eliminated, which prevents the achievement of the desired therapeutic effect.

Some drugs need to enter infusion

  1. In osteochondrosis, the dropper is prescribed in cases where it is necessary that the drug was in the blood in a certain constant concentration. It should not be too high so as not to cause side effects. However, another extreme should be avoided: too low concentration of the drug: in this case, the effect will not be achieved. When administered dropwise, the liquid agent enters the bloodstream gradually, evenly, for quite a long time.
  2. A dropper for osteochondrosis is also placed in case of need for emergency assistance - for example, in case of an exacerbation of the disease, the development of a strong pain syndrome. With this method of administration, the active substances have a faster and more pronounced effect. The doctor monitors the effect of the drug and can decide whether to increase the dose, reduce it, or completely cancel the medicine.
  3. Some drugs are designed specifically for drip. With another method of use, they do not have the proper effect.

Drip administration of mixtures of drugs for osteochondrosis

One of the most important components of the treatment of osteochondrosis is the use of painkillers. They are prescribed a course. In most cases, analgin, sedalgin, paracetamol are used. With a strong attack in the first days, patients are given mixtures of medicines, which include:

  • analgesics,
  • decongestants (dehydrating) drugs
  • anti-inflammatory,
  • muscle relaxants
  • sedatives.
Actovegin for droppers

1 or 2 ml of a 50% solution of dipyrone and analgesic other groups (5-10 ml of baralgin, 20-100 ml of a 0.5% solution of novocaine) are prescribed in most cases with 20-40 ml of hydrocortisone, 10 ml of a 2.4% solution of aminophylline, 20-40 mg lasix, 1-2 ml tranquilizers (for example, Relanium), up to 2000 µg of vitamin B12. When osteochondrosis droppers with these mixtures in various optimally compatible combinations are recommended twice a day.

Novocain and its derivatives are used in various dilutions:

  • sovkain - 0.5-10%,
  • Trimecain - 0.5-0.25%,
  • lidocaine - 0.5.1 or 2%.

In osteochondrosis, infusions of the following mixtures are most commonly used:

  • 50% solution of analgin + no-shpa + lasix + 0.25% solution of novocaine + saline,
  • Baralgin + Relanium + Dexazone + Novocain + Glucose,
  • 50% solution of dipyrone + 2% solution of no-shpy + reopyrin.

Decongestants, or dehydrating, complexes are prescribed mainly in the severity of radicular syndrome. In many cases, it is advisable to use fast-acting saluretics or dexazone. Regarding the efficacy of these medicines, specialists do not have a unanimous opinion.

Often prescribed drugs for drip

The drug is hemoderivate, obtained by dialysis and ultrafiltration. It contains 30% of organic compounds (amino acids, lipids, etc.), as well as trace elements.

In osteochondrosis, droppers with actovegin are prescribed to improve trophism and stimulate the regeneration of damaged tissues.

The drug stimulates the active consumption of oxygen and glucose, thereby increasing the energy potential of the cell and regulates the metabolism of neurons. Improving the diffusion of oxygen in the structures of neurons helps to reduce the severity of trophic disorders.

Actovegin Dropper

Actovegin stimulates peripheral microcirculation, vasodilation (expansion of the lumen of blood vessels), aerobic energy exchange of vessel walls and releases prostacyclin. Due to this effect, the edema of the affected area, hypoxia and microcirculation disorders in the nerve root compression zone are reduced.

In osteochondrosis, Actovegin can be administered intravenously with a dropper. The dosage ranges from 250 to 500 ml per day. The recommended infusion rate is about 2 ml per minute. The full course consists of 10-20 infusions. Since there is a potential for the development of an anaphylactic reaction, it is best to conduct a test before the procedure begins.

Vinpocetine

Droppers with Vinpocetine prescribed for cervical osteochondrosis. This drug contributes to the correction of cerebral circulatory disorders, which in this form of the disease occur very often. Vinpocetine dilates blood vessels and has an antihypoxic effect due to enhanced oxygen and glucose transport. However, it does not have a pronounced effect on the heart and peripheral circulation. The active substance selectively affects the affected areas and improves brain metabolism.

In case of cervical osteochondrosis, Vinpocetine is administered with a dropper. The maximum infusion rate is 80 drops per minute.

The initial dosage should not exceed 20 mg per day, or 2 ampoules. Concentrated product is diluted with a solution for intravenous administration.

In the future, the dose can be adjusted to 50 mg per day. Course duration - 10-14 days.

Ozone Dropper

In osteochondrosis, droppers with ozonized saline are also quite effective. It uses a composition with a fairly low concentration of ozone. This method provides a long-term effect on the internal environment of the body.

Device ozonostat

  • normalize metabolic processes,
  • improve microcirculation
  • restore oxygen transport
  • widen blood vessels
  • reduce the severity of the inflammatory process,
  • strengthen the immune system.

Drip injection of ozonized saline is carried out in two ways:

  • infusion against the background of incessant bubbling - in this case, the solution retains saturation throughout the procedure,
  • infusion with the termination of bubbling during the procedure - while the dose that the body receives in 30 minutes is equal to 67% of the dose received with continuous bubbling.

pharmachologic effect

The effect of aminophylline is due primarily to its theophylline content. Ethylenediamine enhances antispasmodic (relieving spasms) activity and contributes to the dissolution of the drug. Important features of aminophylline are its solubility in water and the possibility of its intravenous administration. Eufillin relaxes the muscles of the bronchi, lowers the resistance of blood vessels, dilates the coronary (heart) vessels, lowers the pressure in the pulmonary artery system, increases the renal blood flow, has a diuretic (diuretic) effect associated mainly with a decrease in canalic reabsorption (reabsorption of water in the renal tubules) causes an increase in urine excretion of water and electrolytes, especially sodium ions and chlorine. The drug greatly inhibits the aggregation (gluing) of platelets.

Blocks adenosine receptors, inhibits phosphodiesterase activity, increases the level of cyclic AMP, reduces - ionized calcium in smooth muscle cells.

Dosage and administration

In case of emergency, adults are administered intravenously (IV) in shock doses at the rate of 5.6 mg / kg of weight (10-20 ml of aminophylline is diluted in 10-20 ml of 0.9% sodium chloride solution, 250-500 ml of physiological solution are added , administered within 30 minutes) and maintenance (0.9 mg / kg for 1 - 3.5 h) doses. If the patient was taking theophylline, the dose should be reduced by 50% or more.

The maximum daily dose in adults is 10-13 mg / kg (0.4-0.5 ml / kg), in children aged 6-17 years - 13 mg / kg of body weight (0.5 ml / kg), from 3 years to 6 years - 20-22 mg / kg (0.8-0.9 ml / kg).

Side effect

Nervous system disorders: dizziness, headache, insomnia, agitation, anxiety, irritability, tremor.

Since the cardiovascular system: heartbeat, tachycardia (including the fetus when taking pregnant in the third trimester), arrhythmias, lowering blood pressure (BP), cardialgia, increasing the frequency of angina attacks.

On the part of the digestive system: gastralgia, nausea, vomiting, gastroesophageal reflux, heartburn, exacerbation of peptic ulcer, diarrhea, with prolonged use - loss of appetite.

Allergic reactions: skin rash, itchy skin, fever.

Other: pain in the chest, tachypnea, sensation of hot flashes to the face, albuminuria, hematuria, hypoglycemia, increased diuresis, increased sweating.

Side effects are reduced by reducing the dose of the drug.

Local reactions: induration, hyperemia, soreness at the injection site.

Overdose

Symptoms: loss of appetite, gastralgia, diarrhea, nausea, vomiting (including with blood), gastrointestinal bleeding, tachypnea, flushing of the skin of the face, tachycardia, ventricular arrhythmias, insomnia, motor agitation, anxiety, photophobia, tremor, convulsions. In severe poisoning, epileptoid seizures may develop (especially in children without any precursors), hypoxia, metabolic acidosis, hyperglycemia, hypokalemia, decreased blood pressure, skeletal muscle necrosis, confusion, renal failure with myoglobinuria.

Treatment: removal of the drug, gastric lavage, the appointment of activated carbon, laxative drugs, siphon enemas with the introduction of a combination of polyethylene glycol and polyelectrolyte solutions, forced diuresis, when the plasma level of the drug is more than 50 μg / ml - hemosorption, plasmapheresis, hemodialysis or peritoneal dialysis are less effective. Symptomatic therapy: perform hemodynamic indicators and respiratory support (oxygen supply and mechanical ventilation). In convulsive syndrome - intramuscular administration of diazepam 0.1-0.3 mg / kg (but not more than 10 mg) the use of barbiturates is contraindicated! With severe nausea and vomiting - metoclopramide or ondansetron (IV). As a specific antidote for intoxication with aminophylline, intravenous injection of Riboxin (Inositol) is used in dilution with saline (do not use glucose or dextrose solutions for dilution).

Interaction with other drugs

Pharmaceutically incompatible with acid solutions.

Increases the likelihood of side effects of GCS, MKS (hypernatremia), means for general anesthesia (increases the risk of ventricular arrhythmias), means that stimulate the central nervous system (increases neurotoxicity).

Rifampicin, phenobarbital, phenytoin, rifampicin, isoniazid, carbamazepine, sulfinpirazon, aminoglutetimid, oral estrogen-containing contraceptives and moracizin, as inducers of microsomal oxidation, increase the clearance of aminophylline, which may require an increase in aminocillin, may increase the dose of aminophylline, may require a dose increase

With simultaneous use of the macrolide group aminophylline may increase, which may require a decrease in its dose.

Enhances the effect of b-blockers and diuretics (including by increasing glomerular filtration), reduces the effectiveness of drugs containing lithium and b-blockers.

In connection with the possibility of potentiating the action of anticoagulants, special care must be taken when they are used together.

Precautionary measures

Intravenous administration should be carried out under the careful control of the blood circulation, respiration and general condition of the patient (heart rate, blood pressure, number of breaths).

The introduction of theophylline derivatives is associated with a high probability of developing a toxic effect due to its low therapeutic latitude.

Determining the content of theophylline is recommended at the beginning of treatment, before a dose increase in the absence of the expected results of treatment, with the use of high doses, with any side effect, with any change in the physiological state, as well as the appointment of a drug that affects the removal of the theophilin or a new drug with an unknown effect on removal of theophylline.

Leads to more side effects and is likely to be less effective in controlling asthma symptoms (including nocturnal).

In the treatment of bronchial asthma, theophylline drugs should not be considered as drugs of choice, they should be used in patients with inadequate response to anti-inflammatory and β-adrenergic drugs.

With an attack of bronchial asthma in adults, a routine IV administration of aminophylline in addition to β therapy2 - Agonists are not shown. This does not lead to an additional bronchodilating effect, but is accompanied by an increase in the frequency of side effects.

Cases of hypotension and cardiac arrest have been reported after rapid insertion through a catheter in the central vein.

Euphyllinum: recommendation for use

The main property of the components of the drug (theophylline and ethylenediamine) is the relaxation of the smooth muscles of various organs in humans, the removal of spasm, which interferes with their proper process, provokes risks to life:

  • respiratory arrest,
  • sharp increase in pressure
  • vasoconstriction
  • poor blood oxygen saturation
  • swelling, including the brain,
  • enhanced uterine contraction and more.

During pregnancy, edema becomes frequent. This condition arises due to an increase in the uterus. The embryo grows and begins to occupy more space. The walls of the uterus squeeze the adjacent organs, vessels. Blood circulation slows down. There is water retention in the body. Pregnant feels discomfort, mainly in the legs. But other parts of the body may suffer.

In a serious situation, preeclampsia develops - a change in the direction of blood flow in all or some of the organs of a pregnant woman. This is usually expressed in an increase in pressure and an increase in the protein content in the urine. If in a normal state (before fertilization), the woman did not have such problems, then high pressure, excess waste fluid in the blood, slow kidney function becomes a threat to both the mother and the embryo (hypoxia, heart failure, vascular elasticity).

The gynecologist decides to prescribe drugs that reduce puffiness during pregnancy. Euphyllinum is used only in cases when other methods have failed. Tablets or droppers is the choice of a doctor who must be motivated by the patient's condition.

Eufillin during pregnancy - tablets or dropper

If safe methods of relieving edema during pregnancy have failed, then the doctor prescribes Eufillin. The dosage is prescribed individually, because the instructions for use do not provide information. It only says that pregnancy, breastfeeding are contraindicated for use if there is no risk to the woman’s life.

Consultation of pregnant woman

With a complex form of preeclampsia, the pregnant woman is sent to the hospital. The introduction of the drug begins with a small dose, gradually increasing it, watching the state of the pregnant woman and the fetus.

In difficult situations, so that the drug entered the bloodstream faster, Eufillin is administered intravenously. Such droppers during pregnancy prescribed in small quantities, because the medicine can cause cardiac arrest. The dropper is administered once, and further treatment is continued with pills, gradually increasing the dose, if necessary.

The medicine dilates the blood vessels. As a result, the outflow of the liquid improves, the content of salts decreases, which also retain water. Edema decreases in the first days of treatment. Weight is lost, which during pregnancy is usually the result of hidden or obvious swelling.

In addition to gestosis, indications for using Eufillin during pregnancy can be a strong uterine tone, which is dangerous to miscarriage. To relieve muscle spasm, the patient is prescribed Euphyllinum.

Important! You can not take eufillin on their own, especially during pregnancy. The drug can cause tachycardia, hypoxia in the fetus.

Therefore, only a doctor under the supervision of an inpatient will prescribe a dropper, pills or injections during pregnancy. It is necessary to monitor the condition of the future mother and the embryo.

Instructions for proper use of dropper with eufillin

If during pregnancy there are reasons that allow the doctor to prescribe Eufillin to the patient, the dosage and method of administration are chosen individually in each case. The instruction attached by the manufacturer to the drug gives information on doses only for adults who do not have a pregnancy. The fact of pregnancy is a contraindication for taking Euphyllinum.

It is advisable that the gynecologist refer the pregnant woman for a course of treatment with Euphyllin to the hospital.

Droppers with aminophylline administered intravenously, starting with a low concentration of the substance. Use ampoules of Euphyllinum, where the substance content is 2.4%. If the vial contains a dosage of 24%, then Eufillin is used only intramuscularly. The drug is diluted in saline and injected very slowly, watching the blood pressure and heart rhythm of the mother and fetus.

The danger of using eufillina during pregnancy

Euphyllinum easily penetrates the placenta and has a serious effect on the embryo. Therefore, the use of medication in the first trimester of pregnancy is undesirable. Edema in women is most often observed in the second half of pregnancy, when the formation of organs in the baby is almost complete. But eufillin can cause adverse reactions in the fetus is much stronger than in pregnant women. Therefore, there is a risk when using this medication during pregnancy.

There are for the reception and other contraindications. If a woman has some symptoms before pregnancy or if it occurs, you should not use Eufillin:

  • low blood pressure
  • tachycardia,
  • arrhythmia,
  • caffeine intolerance,
  • problems in the gastrointestinal tract (gastritis, ulcer),
  • taking drugs that are incompatible with eufillin.

For example, with Dexamethasone, Prednisolone, antidiarrhoeal drugs and many other drugs. A detailed description of the compatibility of Eufillin gives instructions. This is due to the fact that while taking certain drugs, their effect on the body decreases or increases. The combination of Eufillina with Dexamethasone increases the possibility of adverse reactions in the second drug. The use of caffeine-containing drugs increases the absorbability of Euphyllinum.

If a patient is prescribed certain medication in addition to Eufillin, then this must be reported to the gynecologist so that all risks are excluded.

Having studied the characteristics of prescribing Eufillin for pregnant women, it became obvious that this is a serious drug, the use of which should be prescribed only by a doctor if there is such a need. In the practice of physicians, there are other techniques that can solve the problem of edema or other complications during pregnancy. In other cases, the use of droppers, tablets or injections with Euphyllin can be essential to alleviate the serious condition of the patient.

Composition, release form and prescription of the drug

The active ingredient of Euphyllinum is aminophylline (0.025 g), the additional substance is injection water (up to 0.001 l). The medicine is sold in several forms - tablets and injections.

Euphyllinum belongs to the pharmacotherapeutic group of bronchodilating agents, it is used to normalize the peripheral and cerebral blood flow. Prescribed vasodilator drug Eufillin for lung diseases (bronchitis, asthma, emphysema, etc.), disorders of cerebral blood flow (to eliminate intracranial pressure), heart failure. Действие препарата Эуфиллин способствует увеличению силы и частоты сокращений мышц сердца, стимуляции дыхательного цента.

Препарат выпускается в форме таблеток и инъекций.

In the treatment of osteochondrosis, the dropper with aminophylline is prescribed for:

  • Eliminate blood stagnation and improve its circulation in the affected area.
  • Decreased muscle spasms.
  • Normalization of the transmission of nerve impulses.

The effectiveness of the main active ingredient in the expansion of blood vessels, reducing vascular resistance and tone, which helps to improve blood flow through the body, including in the cervical, lumbar, thoracic regions, oxygenation and accelerated delivery to the tissues.

Mechanism of action on the disease

Pain in osteochondrosis can lead to vascular reflex spasm. Pathological bone growths can pinch and irritate arterial, nervous, vascular plexuses, which leads to their narrowing and disruption of normal blood circulation in the tissues of the cervical, thoracic or lumbar spine with osteochondrosis.

The drug Eufillin eliminates the problem of blood stagnation, improves its microcirculation.

The drug Eufillin has a relaxing effect on smooth vascular muscles in osteochondrosis, thereby eliminating the problem of blood stagnation, improves its microcirculation. Due to the increase in the lumen of blood vessels, the drug Eufillin also has an anticoagulant effect. In addition, the improvement of local blood circulation helps to reduce the pain symptom, which is a constant companion of osteochondrosis.

Cost and substitutes: which is better

The cost of a solution of Euphyllinum is rather low — it ranges from 30–70 rubles. In the pharmaceutical market there is only one drug with a similar active ingredient - Aminofillin-Eskom. There are also drugs with a similar therapeutic effect, but other active substances: Diprofillin (solution), Teopek (tablets), etc. However, the cost of analogues is much higher than that of Euphyllinum.

Euphyllinum is an effective drug to improve blood circulation. Due to its vasodilating properties, its use in osteochondrosis helps to eliminate congestive processes, pain and muscle spasms.

What is this drug?

Euphyllinum is an antispasmodic that helps to relax the smooth muscles of the uterus, bronchi, biliary tract. After use, the drug eliminates spasm and muscle contraction. For example, in case of diseases of the bronchi, it reduces bronchospasm, with the threat of miscarriage eliminates unnecessary contractions of the uterus.

The drug Eufillin is produced by several manufacturers. The brand name may differ, because pharmaceutical plants seek to register their own brand. This and Eufillin-Darnitsa, and Eufillin-UBF. But at the same time the composition of the solution does not change. It is produced according to the same formula that was patented many years ago.

Release form

The drug is available in the form of solution for injection and tablets. Solutions are of two types:

  • for intramuscular administration (concentration of 24% aminophylline).
  • for intravenous administration (concentration of 2.4% aminophylline).

Additionally, the composition of the solution includes water and a preservative. The preservative is determined by the formula of the manufacturer.

Action on the body

When using aminophylline improves the work of the muscles between the ribs and ventilation of the alveolar space. The drug enhances the local immune protection of mucous membranes against aggressive pathogenic agents (viruses, bacteria). It expands the lumen of blood vessels, relieving the tension of their walls, reduces the pressure of blood flow in the lungs. The drug improves the work of the heart muscle, increases the production of adrenaline, has a diuretic effect.

Dropper does not form blood clots and prolongs the vital activity of red blood cells in the body. It relaxes the walls of the uterus with contractions of the muscles, threatening preterm labor and abortion.

Indications for treatment

Euphyllinum is recommended if the patient has obstructive pulmonary disease in a chronic form, with asthma, with bronchitis, with apnea. It is used to reduce high intracranial pressure, to eliminate asthma attacks, with impaired blood circulation in the brain, which develops during strokes and swelling of the brain.

Injections of aminophylline intravenously administered if the patient develops acute or chronic heart failure. Such injections reduce the pressure in the vessels of the lungs, relieve swelling in kidney diseases. The medicine helps with neuralgia (as well as Milgamma and its substitutes). It is used in gynecology at the risk of premature birth or at risk of miscarriage. It has a relaxing effect on the smooth muscles of the uterus and relieves spasms.

Contraindications

Euphyllinum has a synthetic nature and a number of contraindications for which it should not be used:

  • It is not recommended to make injections with aminophylline for heart attacks, arrhythmias, tachycardias.
  • Do not put them in attacks of epilepsy, peptic ulcer gastrointestinal (acute phase), with gastritis.
  • There should be no treatment with solution for injection, if the patient has severe liver and kidney diseases, there is a risk of hemorrhage in the retina.
  • It is forbidden to take it in case of intolerance to aminophylline.

Doctors recommend using it with caution for the treatment of children under 14 years old and elderly patients. The risk group also includes nursing mothers, pregnant women, people suffering from atherosclerosis. This treatment is carried out only under the supervision of the attending physician, for any side effects or deterioration of health, the medicine is canceled.

Side Effects of Euphyllin

After taking the medication, patients may experience anxiety, insomnia. They feel dizzy, their limbs cramp, tremors in the muscles begin. At the same time, the work of the heart muscle is disturbed, and a rapid heartbeat begins. After injections, a migraine occurs, the patient is agitated, quickly irritated.

If a woman is pregnant, then heart palpitations and arrhythmia can occur when taking the medicine in the last months of pregnancy. In addition, angina develops, the pressure increases. With a long course of treatment with aminophylline, the appetite may decrease, nausea occurs, there are bouts of vomiting. Sometimes the drug provokes diarrhea or the development of gastric and duodenal ulcers.

  • Side effects can manifest as a rash on the skin, a person is reeling, itching.
  • Sternum pain may develop, diuresis increases, a person sweats a lot.
  • It is often enough to simply reduce the dose of medication in order to reduce the side effects that occur.
  • After puncture of the skin, this area may hurt, swell. There are seals and swelling.

Nuances of application

The drug should be used with caution in heart attacks, angina pectoris, atherosclerosis. Under the supervision of a physician, treatment is carried out for renal and hepatic insufficiency, for gastric ulcer or gastrointestinal Treatment should be monitored for hypothyroidism, thyrotoxicosis, and prostatic hypertrophy.

The drug should be used with caution for the treatment of the elderly and children. This is especially true taking pills.

Reducing the dosage may be necessary in violation of the functioning of the liver, in chronic alcohol dependence, if the person has a fever, in acute respiratory disease. Dose reduction is possible when treatment is prescribed for an elderly person. If you choose an analogue of the drug with the same active substance, then regular analyzes should be carried out to determine its concentration in the blood.

  1. During treatment you should not drink strong brewed tea and coffee, take theophylline derivatives and purine.
  2. Do not combine the drug with beta-blockers.
  3. It is not recommended to make injections if driving or other mechanisms is to be carried out. The ingredients of the drug, absorbed into the bloodstream, dispel attention, the sharpness of reactions is lost.

Medicine during pregnancy

The instructions for use spelled out that its use at this time may threaten the health of the child. In the blood of a newborn, doctors often detect a greater concentration of caffeine and aminophylline.

If the mother is undergoing a course of injections with this drug, but the children after birth are watched by doctors to rule out xanthine intoxication. When taking aminophylline, doctors conduct an assessment of the risks and possible consequences. The drug is prescribed for extreme vital signs.

Why pregnant women prescribed aminophylline?

Indications during gestation:

  • Swelling of tissues.
  • Placental insufficiency.
  • Gestosis.
  • The threat of miscarriage or premature birth.

Pregnancy in the annotation is registered as a contraindication, so there is no clear treatment regimen. The doctor prescribes the dosage and schedule of admission, based on the diagnosis of the woman, her state of health. In pregnant women, during a course of treatment, a strong heartbeat may begin, weakness is observed.

Electrophoresis with the drug

This procedure is performed for people of any age to relax muscles, reduce intracranial pressure. It is used in the treatment of diseases of the joints. Electrophoresis is used to improve the blood supply in certain areas (neck, lower back). It acts pointwise, without a systemic effect. Therefore, the procedure is applied even for infants and is well tolerated by all groups of patients.

For electrophoresis, a piece of gauze is wetted in the drug (at a concentration of 2, 4%), electrodes are applied to the desired area. During the procedure, the patient feels warm or tingling. The course of treatment is 10 sessions of 10-15 minutes. The procedure is done every other day, then you need a break.

Euphyllinum and alcoholic beverages

The drug is not combined with alcohol, because it enhances the toxic effect on the body, increasing the effects of the drug. Against this background, the pressure drops, suffocation begins, the heartbeat quickens, arrhythmia and tachycardia develop. Due to the relaxation of the muscles of the lungs, sometimes a complete cessation of breathing occurs, and hemorrhages are possible with weakened vessels of the brain. In rare cases, taking alcohol and euphyllinum simultaneously provokes a lethal outcome.

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