Domestic drug azipol is a bacterium probiotic preparation containing live cultures of lactic acid bacteria and polysaccharides of Tibetan milk (kefir) fungi. It is extremely intolerant of pathogenic and disguised as decent, but always ready to organize dysbacteriotic “putsch” microorganisms. Intestinal dysbiosis is a problem of millions of people. Many suffer from it, even without being aware of the tectonic changes that occur with their own bacterial microflora. The imbalance of the latter inevitably impairs digestion, absorption and assimilation of food in all intestinal “milestones”, significantly worsens the immune status and aggravates the patient’s general health. The most obvious signs of intestinal dysbiosis are known by a little less than all: discomfort (heaviness, rumbling, bloating) in the stomach, constipation or diarrhea, poor appetite, nausea, persistent fatigue, drowsiness. If you do not respond properly to these symptomatic bells, you can wait for the real pathogenetic bell in the form of anemia, significant loss of vitality, toxic headaches, sleep disorders, deterioration of appearance (fragility and loss of hair, acne on the skin, corners in the mouth) . In children suffering from chronic intestinal dysbiosis, the growth and development of the body is slowed down. One of the most effective drugs in the treatment and prevention of intestinal dysbacteriosis is the probiotic drug acipol. Probiotics include live microorganisms that have a positive effect on health in general and the state of the intestinal microflora in particular. Atsipol is a combined probiotic in which microorganisms - living lactobacilli - are found in conjunction with components of the nutrient medium - kefir polysaccharides. The former promote the growth of normal intestinal microflora, restoring the disturbed balance between populations of bacterial strains. The latter improve the immune status of the organism, showing an immunomodulating effect.
Lactobacilli of the drug are not destroyed in the aggressive-acidic environment of the stomach, reaching the intestine with the least loss of "numerical composition" and ensuring the rapid deployment of "military units" (read: the rapid onset of therapeutic action). Atsipol is a drug with almost no negative side effects. The favorable safety profile allows you to assign it to children from the age of 3 months. In addition to this, it should be added that acipol is included in the Industry Standard for the “Patient Management Protocol. Intestinal Dysbacteriosis”.
Atsipol is produced by the Russian pharmaceutical company Pharmstandard in encapsulated form. The daily dose and duration of the drug course are set individually in each specific clinical case and are determined by the patient's age, the severity and duration of the disease and the severity of dysbacteriosis. Children falling under the age limit of "+3", acipol prescribed 1 capsule 2-3 times a day during meals. It is not necessary to swallow the capsule entirely for such young patients: it is opened before taking it, and its content is dissolved in boiled water or milk at room temperature. Adults and children aged 3 years and older are prescribed 1 capsule 3-4 times a day for half an hour before meals. In infectious diseases of the intestine of viral and bacterial etiology, abbreviated as "OKA (" acute intestinal infections ") acipol should be used in exchange rate mode for 5-8 days. Longer drug courses are indicated for children with chronic dysbacteriosis, resulting in a lag in weight and height. In order to prevent gastrointestinal symptoms of acipol, it is recommended to use 1 capsule once a day for two weeks. The minimum time interval between repeated pharmacotherapeutic courses (if necessary) must be at least 1 month. Adults and children over 3 years old take capsules whole, washed down with boiled water.
Pharmacodynamics and pharmacokinetics
Kefir fungusthanks to a special polysaccharides in composition, creates an unfavorable atmosphere for development pathogenic microorganisms. This is due to the effect of the drug, which is close to the effects of antibiotics. Also, the drug speeds up immune response organism.
Lowering overall pH, lactobacillus contribute to the binding of the destructive for the body, ammonia with hydrogen (the reaction occurs mainly in an acidic environment) and its unhindered conclusions from the body in a natural way, that is, along with feces.
As it is known in the intestine, a synthesis of important of vitamins andbioactive substances. Also in the intestine should be quickly and efficiently digested food, absorbed from it ingested vitamins and nutrients. An important factor in the normal functioning GIT is good peristalsis and intestinal motility. Atsipol normalizes all these processes. The pharmacokinetics of the drug has not yet been precisely studied.
What pills Atsipol?
- acute intestinal infectionsaicaused by gram-positive and gram-negative bacteria,
- chronic colitis, enterocolitis, bowel disorders,
- acute and chronic dysbacteriosisaccompanied by reduced immunitybut, weaknesses, constipationx and diarrhea.
It also serves as an indication for Atsipol:
- medication that may cause dysbacteriosis and various intestinal disorders,
- at allergiesto reduce intoxication.
Analogs of Acipol
Analogues of drugs are other eubioticswith a similar active ingredient. Such as Biobacton, Linex, Bifidumbacterin, Hilak Forte and other drugs normalizing intestinal microflora.
The use of candles has a similar effect. acylact. The composition of the acylact suppositories is similar to that of Acipol, except for excipients (due to the dosage form).
What is better Acipol or Linex?
Atsipol contains bacteria of the same species. And in Linx there are three of them at once, which means it is more efficient. The number of acido, lacto - and bifidobacteria in the analogue is much higher than Atsipol. But, at the same time, the advantage of Acipol can be considered low costThere is also the fact that all microorganisms trapped in the body will retain their capacity.
What is better Acipol or Hilak forte?
Hilak forte a well-known medium often mentioned in advertising. The drug is prebioticmit only regulates normalization. microfloraAs a rule, not effective for young children.
Atsipol for children from three years prescribed in the amount of 3 capsules per day. To make it easier for the child to swallow the medicine, it is usually dissolved in water or milk. The drug has positive feedback when constipation in children. It is safe, non-toxic and well absorbed. The price of the drug for children is not so high.
Atsipol for newborns is prescribed most often when allergiescaused by an imbalance in the intestinal microflora of the mother and child. The course and dosage should be prescribed by the doctor, before taking the capsule is dissolved in milk. The reviews for newborns are positive, the medicine copes well with the task of adapting the GTC to self-feeding.
Reviews of Acipol
Reviews on the forums: both negative and positive. The effectiveness of the drug is high, if prescribed by a doctor, as part of a comprehensive treatment. Patients who began to drink the medicine on the advice of friends and acquaintances, most often did not observe significant improvements and independently stopped taking.
Reviews during pregnancy: helps well to cope with dysbiosis during pregnancy, great as a prophylactic.
When taken by children and babies, the following reviews: in general, the drug is well tolerated, although it sometimes occurs in children flatulence. The drug for infants helps ZhTK to get used to the new type of food.
Reviews on the use of Atsipol to children from three years old are good, the medicine is effective when stomach disorders.
Forms of release and name
Currently Atsipol is available in a single dosage form - capsules for ingestion. Capsules Atsipol are oblong gelatin cylinders, consisting of two parts. Inside the capsules is a dry powder, painted in a light cream or cream color and having a characteristic fermented milk smell. The drug is available in plastic opaque jars of 10, 20 or 30 capsules.
Earlier, a few years ago, Acipol was also produced in tablets and lyophilisate, but at present the production of these dosage forms is discontinued, since in their qualities they are significantly inferior to capsules.
Thus, the Atsipol tablets were a compressed lyophilisate, so they had to be chewed in the mouth and washed down with water or milk. And the lyophilisate was a powder that, before taking, had to be diluted in 5-10 ml of water or milk and the resulting suspension was drunk. In such cases of taking the drug, most of the microorganisms died in the stomach, because they could not withstand the effects of acid, and only a small amount of bacteria of normal microflora reached the intestine.
Capsules Atsipol have a huge advantage over tablets and lyophilisate, since their shell protects microorganisms from the effects of gastric juice and dissolves only in the intestine, releasing beneficial bacteria exactly where it is needed. That is, in the capsule all the bacteria of the drug reach the intestine, which provides a much faster cure and normalization of the condition.
In principle, inside the capsules is a powder, which is the same lyophilisate, which was previously produced as an independent dosage form and from which the tablets were pressed. That is, in addition to better delivery of the active ingredients in the intestine, the capsules are no different from tablets and lyophilisate.
Quite often, people are looking for candles Acipol, but the drug was never released in this dosage form. Most often under the candle Atsipol understand and imply a drug analogue - candles Atsilakt. In this case, there is confusion provoked by the similarity of the names "Atsipol" and "Atsilakt".
Acipol contains dried live acidophilic lactobacilli and kefir polysaccharides as active components. This means that first lactobacilli were grown in a nutrient medium, after which they were dried in a special way, that is, they were subjected to freeze-drying. Lactobacilli, subjected to the procedure of lyophilization, remain alive, but turned into an inactive state. If you add water or milk to lyophilized lactobacilli, then after 4 to 5 hours they will become active again. This means that Atsipol contains live lactobacilli, which are able to colonize the intestine and eliminate dysbacteriosis.
Kefir polysaccharides are substances produced by these microorganisms as a result of their vital activity and remaining in the nutrient medium. This means that in order to obtain them, kefir fungus was first grown, after which it was inactivated so that it does not multiply again, and then the entire available nutrient medium was lyophilized. As a result, substances produced by the kefir fungus appear in the lyophilisate.
These substances are an excellent nutrient substrate for bacteria of the normal intestinal microflora, thanks to which they can multiply quickly and well, colonizing the intestines and preventing the development of dysbacteriosis. That is, in fact, polysaccharides of kefir fungus are prebiotic substances. Acidophilic lactobacilli are microorganisms that are normally part of the human intestinal microflora. That is, the presence of lactobacilli in the composition makes Atsipol capsules the drug of the probiotic group. Thus, the presence of probiotics and prebiotics in Atsipol at the same time makes this preparation a synbiotic.
In addition to the active components in the capsules Atsipol as auxiliary substances include titanium dioxide, gelatin and red iron oxide. These excipients are used for the production of capsules.
Since Atsipol contains both probiotic (lactobacilli) and prebiotic (kefir polysaccharide fungus), both therapeutic effects and action are determined by the properties of these components.
Lactobacilli that are part of Atsipol have the following therapeutic effects:
- Pathogenic and conditionally pathogenic microbes in the lumen of the intestine (for example, shigella, pathogenic Escherichia coli, Proteus, Dysenteric bacilli, Salmonella, Klebsiella, Yersinia, Staphylococcus, etc.) are detrimental. Thanks to this action, alien microflora is destroyed, intestinal infections and dysbacteriosis are cured,
- They produce lactic acid, lowering the acidity of intestinal contents, which also creates favorable conditions for representatives of normal microflora and acts detrimentally on pathogenic and conditionally pathogenic bacteria. This effect also cures intestinal infections and eliminates dysbiosis,
- Synthesize B vitamins,
- Increase the body's resistance to various pathogens of infectious diseases,
- Disaccharides are cleaved, such as lactose, galactose, glucose, fructose, maltose, sucrose, cellobiose, mannose, trihalose and salicin. Consequently, Atsipol can be prescribed as a means of substitution therapy for lactase deficiency,
- Strengthen the general body resistance to various diseases.
All the listed therapeutic effects of lactobacilli are very strong and are expressed due to the polysaccharides of kefir fungus, also part of Acipol. After all, these polysaccharides are actually a nutrient substrate for lactobacilli. Thus, when taking Acipol, a person simultaneously receives both normal microflora bacteria and nutrients for better engraftment, growth and reproduction.
In addition, polysaccharides of kefir fungus have an additional therapeutic effect, which consists in a direct stimulating effect on the immune system, as a result of which its work is activated and it becomes possible to cure long-term current chronic infectious and inflammatory processes in various organs and systems of the body. Polysaccharides of kefir fungus increase the number of lymphocytes by activating the process of their maturation in the thymus and spleen.
Atsipol - indications for use
The general indication for the use of Atsipol is dysbacteriosis, which has arisen for various reasons in various organs (intestines, vagina, mucous membrane of the oropharynx and respiratory tract, etc.). It should be remembered that dysbacteriosis of any mucous membrane can be cured only after normalization of the intestinal microflora. Therefore, Atsipol, normalizing the intestinal microflora, indirectly leads to the elimination of dysbacteriosis and other organs (mouth, nasopharynx, bronchi, etc.).
More accurate and specific indications for use of Acipol as the primary means of therapy are the following conditions or diseases in children and adults, leading to dysbiosis:
1. Acute intestinal infections (for example, rotavirus infection, salmonellosis, dysentery and others), including unspecified,
2. Chronic colitis and enterocolitis of infectious or non-infectious genesis,
3. Intestinal disorders and disorders of the digestive tract, provoked by opportunistic microorganisms, such as staphylococcus, Klebsiella, etc.
4. Long-term use of antibiotics.
In addition, Acipol is indicated for use. as part of complex therapy in the following diseases, accompanied by dysbiosis and lag in the set of body weight in children:
- Active and massive antibiotic therapy for purulent and inflammatory diseases of various organs and systems in infants,
- Chronic, long-lasting or recurrent respiratory infections (for example, bronchitis, pneumonia, laryngitis, tracheitis, etc.),
- Atopic dermatitis and other allergic diseases or reactions.
Separately, it is worth mentioning the indications for use of Atsipol, which consists in increasing the general body resistance to diseases and preventing dysbacteriosis against the background of various factors and situations that can lead to an imbalance of microflora, such as for example stresses, errors in diet, antibiotics, colds, flu and etc. As a means of increasing resistance to diseases, Atsipol is recommended to be used with a tendency to frequent, prolonged, chronic or recurrent pathologies of the gastrointestinal tract and respiratory tract.
Before using and taking the capsules, carefully inspect the packaging (plastic white opaque jar) and the appearance of the red shell of each capsule.If the jar in which the capsules are placed has damage (for example, cracked), there is no marking on it, the marking with the expiration date is missing or not clearly visible, then such a preparation cannot be used, since most likely the person is dealing with counterfeit.
Also, capsules with an expired shelf life should not be taken, since their therapeutic effect will be very low. Indeed, after the expiration date, the beneficial bacteria contained in the capsules simply die, and the drug loses its effectiveness.
You should not take Acipol capsules packed in damaged blisters (long flat foil packs or paper in which tablets are often found — see the picture below), because they could lose their properties.
If the capsule shape is broken or there are any inclusions and dots in its color, then such a preparation should also not be taken.
Atsipol should be taken at the same time with other drugs prescribed for the treatment of an existing condition or disease. It is not recommended to postpone the use of Atsipol for the period after the completion of therapy with other drugs, since this approach only aggravates dysbacteriosis and lengthens the period of time necessary for its elimination.
Capsules Atsipol should be taken orally, swallowing them whole, not clearing through, not chewing or crushing in other ways. The capsule must be washed down with at least half a glass of water, milk, or a fermented milk product (ryazhenka, yogurt, kefir, bifidok, etc.) at room temperature.
If Atsipol is given to an infant who is not yet able to swallow the whole capsule, first it is opened, the contents are poured into a spoon or a small container (for example, a glass), 10 ml of water (one teaspoon) are added and slightly stirred until a homogeneous, homogeneous suspensions. The resulting suspension give the baby. If the child swallows the suspension from a spoon, then you can give him Atsipol this way. If the child refuses to swallow the suspension from a spoon, then it is added to a small amount (20–30 ml) of expressed breast milk or an artificial formula and given to the child in a bottle.
Optimally take the drug for 30 - 40 minutes before meals. However, when using Atsipol for infants, they should be given the drug with food during the next feeding. Along with food, you can give Acipol to a child under the age of three. But after reaching three years, it is necessary to withstand the interval between taking the capsules of Acipol and food for at least 15 minutes.
The dosage and duration of therapy with Acipol is usually determined by the doctor based on the severity of the course of the disease and the rate at which improvements appear, taking into account the individual characteristics of the organism. However, there are developed averaged recommended dosages and durations of courses of therapy for various conditions and diseases, which can be oriented.
Atsipol with a therapeutic purpose for any diseases should be taken in the following dosages depending on age:
- Children aged 3 months - 3 years - take one capsule 2 to 3 times a day with food,
- Children over 3 years old and adults - take one capsule 3-4 times a day, half an hour before meals.
If necessary, you can increase the daily dosage to 9 capsules for kids under 3 years old and up to 12 capsules for adults and children over 3 years of age.
It should maintain approximately the same time intervals between capsules. For example, when taking capsules twice a day, it is recommended to take them in 10 - 12 hours, that is, in the morning after waking up and in the evening before going to bed. When taking capsules three times, it is recommended to drink them approximately every 8 hours, etc.
In acute conditions and diseases (for example, acute intestinal infection, acute bronchitis, ARVI, flu, etc.) Atsipol is recommended to be taken within 5 to 8 days. Moreover, the sooner after the onset of the disease, Acipol is started, the better for humans. With ARVI, flu and other acute diseases of the respiratory or digestive organs, Acipol should be taken simultaneously with other drugs, and not wait for the end of the main course of treatment. With such an application, a 5–8 day course of therapy with Atsipol is sufficient to restore the microflora balance and eliminate dysbacteriosis. If, however, capsules are used after the completion of the treatment of acute infections with other drugs, then it will take at least 10 days to restore the balance of microflora and eliminate dysbiosis.
With long-term current, chronic, recurrent diseases (for example, enteritis, colitis, bronchitis, persistent dysfunction of the intestines, etc.), as well as in infants with a lack of body weight Atsipol should be used in long courses of 2 - 3 weeks. If necessary, treatment can be extended to 3 months.
In chronic diseases or persistent dysbacteriosis, difficult to correct, courses of therapy with Acipol can be repeated. Between two consecutive courses of taking Acipol, one should withstand an interval of at least one month.
For the prevention of dysbiosis and functional disorders of the intestine, Acipol should be taken at any age, one capsule once a day, for 10 to 15 days. Prophylactic courses for taking Acipol can be performed 3-5 times per calendar year.
Atsipol for children
Capsules Atsipol can be used in children from three months of age. Previously, it is not recommended to give the child Atsipol, since it contains only lactobacilli and there are no bifidobacteria, which can disrupt the normal relationship between these types of bacteria in the intestine and provoke diarrhea in the baby. Upon reaching three months, it is no longer possible to upset the balance between bifidobacteria and lactobacteria in the intestines of a child, because his body acquires the ability to independently regulate this parameter. In this case, even if the child receives more lactic acid bacteria with the capsules of Atsipol than he needs, they will simply be removed from the intestine with feces.
Atsipol is used in children, as in adults, to eliminate dysbacteriosis caused by any reasons, and to treat intestinal infections. We should also dwell on the use of the drug for the treatment of dysbacteriosis. The fact is that a child has practically any violation of the diet, stress suffered from acute respiratory viral infections, acute respiratory infections or inflammatory diseases of any organ (including bronchitis, tonsillitis, laryngitis, pharyngitis, etc.) always provoke dysbacteriosis of one degree or another. . Therefore, so that after the illness the child does not become ill often and does not acquire chronic pathology, dysbacteriosis should be eliminated. For this purpose, perfect capsules Atsipol.
French pediatricians recommend that during the treatment of any cold, flu, acute respiratory infections or infectious inflammatory diseases of various organs (bronchitis, tonsillitis, otitis, urethritis, etc.), in addition to the main drugs, give the child any probiotics, including Atsipol. As shown by studies conducted in Russian clinics, such use of Acipol accelerates recovery and reduces the incidence of diseases in young children. Therefore, it is recommended to use Atsipol in children with various infectious and inflammatory diseases of any organs even before signs of dysbacteriosis appear.
In addition, a separate mention should be made of the benefits of using Atsipol in infants suffering from lactose intolerance. If the baby suffers from this condition, it is possible to give him half a capsule of Atsipol before feeding, and the symptoms of lactose intolerance will disappear, since the bacteria contained in the preparation are able to break down and digest milk sugar. This means that against the background of the use of Atsipol, it will be possible to continue breastfeeding and not transfer the child to a lactose-free mixture.
The entire set of reasons for the use of Acipol in children can be divided into two large groups - preventive and therapeutic drug intake. When treating Acipol, it should be given to children under three years old, one capsule 2 to 3 times a day with meals. Children over three years old - 1 capsule 3-4 times a day 30 minutes before meals. The duration of therapy depends on the rate of improvement and is on average 5–8 days for acute infections (intestinal infection, influenza, SARS, acute respiratory infections, etc.), and for chronic or long-lasting diseases (colitis, enteritis, bronchitis, etc.) d.) - 2 - 3 weeks.
When prophylactic use of Atsipol in children of any age should be given to them, one capsule per day during or 30 minutes before meals for 10-15 days. Prophylactically, the child can be given a drug after any infectious-inflammatory disease of various organs.
The capsule in its entirety should be given to children only if it can be swallowed. In this case, you need to give kids Atsipol half an hour before meals. It is necessary to ensure that the child swallows the capsule and washed it down with half a glass of water or milk.
If the child cannot swallow the capsule, then it is opened, the contents are poured into a spoon, 5-10 ml of water or milk are added and mixed well to obtain a homogeneous turbid suspension. This suspension is given to the child to drink. With this version of the use of capsules, Acipol is given to the baby during meals.
To eliminate lactose intolerance, you must give the baby half a capsule before each feeding. To do this, open the capsule, pour the contents on a clean plate, divide it in half. Then, one half of the powder is diluted in a spoonful of boiled water at room temperature until a turbid suspension is obtained and given to the child before feeding. If the child does not swallow the contents of the spoon, the suspension should be diluted in 10 - 30 ml of milk or a mixture. The suspension is given to the baby at the beginning of feeding, and when he eats everything, he is breastfed or with the required amount of artificial formula.
How to take Atsipol baby
Atsipol babies should be given in the form of a suspension during meals. To obtain a suspension, open the capsule, pour its contents into a spoon and add 5 - 10 ml of water (a teaspoon). Stir the water and powder from the capsule until a cloudy suspension is obtained. Then this suspension should try to give the child directly from the spoon. If he swallows it, then immediately after that you need to start feeding, giving him a breast or a prepared bottle with the mixture. If the child does not swallow Atsipol suspension from a spoon, then it should be mixed with 10 - 30 ml of the mixture or expressed breast milk and poured into a bottle. This bottle is given to the child, and when he completely eats its contents, he is breastfed or with the required amount of the mixture.
For the treatment of various diseases, babies are given one capsule 2 to 3 times a day for 5 to 20 days. For prophylaxis, give 1 capsule 1 time per day for 10-15 days.
Use during pregnancy
Practicing doctors and scientists believe that Atsipol is safe for pregnant women, because it contains bacteria of normal microflora and waste products of kefir fungus. Both components do not harm the fetus and the woman herself, and therefore can be considered safe.
However, the instructions for use indicate that there is no data on the use of pregnancy. This phrase should not be feared, since it reflects only the fact that manufacturers did not conduct special studies of the drug in pregnant women. But common sense dictates that kefir and lactobacilli that a woman can receive during the entire pregnancy with the corresponding dairy products are not capable of causing any harm to her or the baby. Therefore, if you are guided by common sense, and not by international requirements for writing instructions, then Acipol can be used by pregnant women, as practitioners and scientists say.
Side effects and contraindications
Contraindications to the use of Acipol is intolerance to the components of the drug. With caution should use the drug for candidiasis (thrush), because it can provoke its exacerbation or weighting of the course.
As side effects, Acipol can provoke only various allergic reactions, with the development of which it is necessary to stop taking the drug.
Antsipol analogues are considered drugs, which as active ingredients also contain any types of lactobacilli. Moreover, analogues can contain only lactobacilli or a combination of lactobacilli, bifidobacteria, enterobacteria and prebiotics.
So, to the analogs of Acipol include the following drugs:
- Acylact (lactobacillus only),
- Biobactone (Lactobacillus only),
- Bonolact Pro + Biotic,
- Bonolact Re + General,
- Darm-Symbioten Pasco,
- Yogulakt and Yogulakt Forte,
- Lactobacterin (Lactobacillus only),
- Narine (lactobacilli only),
- Normoflorin –L,
- Primadophilus (Lactobacillus only),
- Regulin (lactobacillus only),
- Rela-Life (lactobacillus only),
- Santa Rus B,
- Trilact (lactobacillus only),
- Euflorin - L (lactobacillus only),
- Effidigest (lactobacillus only).
Brackets indicate which drugs contain only lactobacilli.
Bifiform or Acipol?
Bifiform contains in the composition of bifidobacteria, and Atsipol - lactobacilli. That is, the preparations contain different types of bacteria, which are components of normal microflora and have somewhat excellent properties. Thus, Atsipol is effective for the treatment of viral infections, and Bifiform - for the elimination of thrush and bacterial infections. Therefore, you should choose drugs on the basis of what kind of disease a person has.
In dysbacteriosis, it is optimal to first apply Atsipol and then Bifidumbacterin, since it is in this sequence that the maximum recovery of normal microflora is achieved.
Read more about the drug Bifiform
Author: Nasedkina A.K.Specialist in conducting research on biomedical problems.
Pharmacological properties of the drug
Capsules of Atsipol have a pronounced antimicrobial action against pathogenic intestinal microflora, which, multiplying, cause digestive disorders and infectious diseases.
The suppression of the growth of pathogenic bacteria in the intestine occurs due to the multiplication of lacto and bifidobacteria, which create unfavorable survival conditions for the pathogenic flora. By increasing the number of beneficial microbes in the intestine, the patient’s immunity and ability to withstand various viral and infectious diseases is increased.
Part of the capsule of the drug Lactobacilli during reproduction change the pH level of the intestine, which causes growth inhibition for pathogenic pathological microorganisms.
When normal intestinal microflora is restored, the production and absorption of B, K vitamins and other biologically active substances is normalized. Against the background of the restored microflora, cholesterol and bilirubin levels normalize due to Acipol capsules in the blood. Regular use of the drug in therapeutic and prophylactic doses improves the digestive processes, relieves the patient from such unpleasant phenomena as nausea, belching, heartburn, flatulence and increased gas formation, constant rumbling in the abdomen. Thanks to the lacto and bifidobacteria that are part of the Atsipol capsule, the intestinal function is improved, the peristalsis is improved, which serves to prevent chronic constipation and rotting processes in the large intestine.
Indications for use of the drug
Capsules Atsipol prescribed to patients for the prevention and treatment of the following conditions:
- Chronic constipation due to decreased intestinal motility,
- As part of complex therapy for acute poisoning, accompanied by diarrhea,
- Salmonellosis, dysentery, acute intestinal infections, as a result of which the patient’s body is dehydrated, and together with the feces beneficial microorganisms are derived,
- Enterocolitis with severe bowel function disorders,
- Dysbacteriosis caused by long-term antibiotics,
- Frequent infectious and viral infections,
- Comprehensive treatment of allergic skin eruptions, atopic and contact dermatitis,
- Monotonous poor nutrition.
Dosage and administration of the drug for children
The dosage of the drug and the duration of the course of therapy is determined by the doctor for each individual patient individually. This largely depends on the patient's age, body weight, diagnosis, and severity of the disease.
Children over the age of 3 months are prescribed 1 capsule of the drug 2 times a day before feeding or during meals. Since babies often cannot swallow a capsule, it can be opened and the contents mixed in 1 teaspoon of warm boiled water.
For babies up to 3 months, it is recommended to take ½ of the contents of the capsule, after dissolving it in water.
Детям старше 3 лет рекомендуется принимать по 1 капсуле 3 раза в сутки во время еды или за полчаса до приема пищи.
In order to prevent the development of dysbacteriosis as a result of treatment with antibiotics or other drugs, a course of treatment with Atsipol for at least 2 weeks, 1 capsule 2 times a day is recommended.
The minimum course of therapy is at least 10 days, the maximum 1 month. If necessary, drug treatment can be repeated after 1 month according to the scheme indicated by the doctor.
Use of the drug during pregnancy and breastfeeding
The drug Atsipol can be used for the treatment and prevention of the above conditions during pregnancy and lactation. While breastfeeding, the baby’s reaction should be monitored, since with frequent or prolonged use of probiotics, babies may develop an allergic skin rash.
With simultaneous use of Atsipol capsules and dairy products to restore the intestinal microflora, the effect of the drug is enhanced.
It is not recommended to take probiotic capsules at the same time as antibiotics, since in this case drugs suppress the growth and reproduction of lacto and bifidobacteria and there will be no therapeutic effect from such treatment. Probiotics are recommended to be taken after the end of the course of treatment with antibiotics. During therapy with small children, if it is necessary to dilute the contents of the capsule with water, care should be taken that the fluid temperature does not exceed body temperature, otherwise it will lead to the death of beneficial bacteria and the lack of a therapeutic effect.
Conditions of storage and release of the drug
Capsules Atsipol dispensed in pharmacies without a prescription. The drug should be stored in the refrigerator or other cold place where the temperature does not exceed 10 degrees Celsius. The shelf life of the capsules is 2 years from the date of the date of manufacture of the drug, which is indicated on the carton. Avoid direct sunlight on the bottle with capsules, as this can lead to the death of lactobacilli.
Analogues with the same composition does not currently exist.
Analogues of the pharmacological group (means normalizing the intestinal microflora): Acilact tablets, Bactisubtil, Bifidumbacterin, Bifidumbacterin dry, Bifidumbacterin forte, Bifikol, Bifidumbis, Bifiform, Goodluck, Lactofilterrum, Linex, Primadofilus, Try out to be gravitated.