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Vinpocetine - instructions for use


In this medical article can be found with the drug Vinpocetine. Instructions for use will explain in what cases you can take pills and shots, which helps the medicine, what are the indications for use, contraindications and side effects. The annotation presents the release form of the drug and its composition.

In the article, doctors and consumers can leave only real reviews about Vinpocetine, from which you can find out whether the medicine has helped in the treatment of the effects of stroke and other vascular diseases in adults and children, for which it is prescribed. The manual lists analogues of Vinpocetine, the prices of the drug in pharmacies, as well as its use during pregnancy.

Anti-aggregation, anti-hypoxic and vasodilator drug is Vinpocetin. Instructions for use offers to take tablets 5 mg and 10 mg forte, injections in ampoules for injection in case of acute and chronic disorders of cerebral circulation, with neurological and mental disorders in patients with cerebrovascular insufficiency, with vascular eye diseases.

Release form and composition

In pharmacies with a prescription, you can buy Vinpocetine in dosage forms:

  1. 5 mg tablets
  2. concentrate for solution for infusion 5 mg / ml, 2 ml each in ampoules of dark glass,
  3. injection of 5 mg / ml, 2 ml each in ampoules of dark glass (shots).

The active substance of the drug - Vinpocetine.

pharmachologic effect

Vinpocetine instructions for use refers to the means with vasodilator, antiaggregatory, antihypoxic effect. The drug improves cerebral circulation, has a relaxing effect on the smooth muscles of blood vessels in the brain and stimulates, above all, the blood supply to ischemic areas, without changing the intensity of blood supply in intact areas.

Reception means leads to the expansion of blood vessels of the brain and increased blood flow. As a result of using Vinpocetine, the supply of brain tissues with oxygen and energy substrates improves, tissue metabolism switches to an energetically more favorable aerobic direction, and the tolerance of hypoxia to brain tissues improves. The drug slightly reduces systemic blood pressure.

The drug increases the content in the brain tissues of cAMP and ATP, as well as catecholamines, namely dopamine and noradrenaline. When it is taken, the functional activity of transmembrane sodium and calcium channels, NMDA and AMPA receptors is reduced.

Efficacy and Bioavailability

Vinpocetine tablets and other forms of the drug increase the deformability of red blood cells and reduce platelet aggregation, thereby reducing blood viscosity. The active ingredient of the drug has an antioxidant effect, and also provides a neuroprotective effect.

Vinpocetine, when ingested, is rapidly and completely absorbed from the gastrointestinal tract. Bioavailability of the drug is 50 - 70%. The active substance has the ability to pass through the placenta and penetrate into breast milk.

In the liver it is biotransformed to metabolites, the main of which, apovincaminic acid, is characterized by a certain pharmacological activity. The removal of this drug from the body by the kidneys in the urine is mainly in the form of metabolites, a small amount is excreted unchanged.

What is Vinpocetine prescribed for?

Indications for use of medications include:

  • vegetovascular dystonia in menopausal syndrome,
  • chronic and acute cerebrovascular insufficiency,
  • Meniere's disease, hearing impairment of toxic or vascular origin, dizziness of labyrinth origin,
  • posttraumatic encephalopathy,
  • vascular diseases of the choroid and retina,
  • dyscirculatory encephalopathy, accompanied by headache, dizziness, memory impairment.

Vinpocetine (tablets)

Inside 5 mg (1 tablet) after a meal. The drug is used 3 times a day. The initial daily dose is 15 mg. The maximum daily dose of 30 mg. Duration of treatment up to 3 months. Possible repeated courses 2-3 times a year.

In diseases of the kidneys or liver, the drug is prescribed in the usual dose. Before cancellation, the dosage of the drug should be gradually reduced.

Intravenous drip (infusion rate should not exceed 80 drops / min). The initial daily dose is 20 mg (dissolved in 0.5-1 l of 0.9% sodium chloride solution or solutions containing dextrose). The average daily dose for a body weight of 70 kg - 50 mg.

With good tolerance for 2-3 days, the dose is increased to the maximum - 1 mg / kg per day. The course of treatment is 10-14 days. After achieving improvement, they switch to ingestion of the drug.


  • lactase deficiency
  • intolerance to galactose,
  • hypersensitivity to any of the components of the drug Vinpocetine, from which tablets and shots can cause side effects,
  • children under 18 (due to insufficient data),
  • pregnancy (possibly placental bleeding and spontaneous abortions, probably as a result of increased placental blood supply),
  • glucose-galactose malabsorption,
  • lactation period
  • acute phase of hemorrhagic stroke, ischemic heart disease, marked arrhythmias.

Side effects

  • skin allergies,
  • nausea,
  • general weakness
  • dizziness,
  • heartburn,
  • dry mouth
  • headache,
  • tidal sensation
  • ECG change (ST depression, prolongation of the QT interval),
  • increased sweating
  • extrasystole
  • tachycardia,
  • blood pressure lability
  • sleep disorders (insomnia, increased sleepiness).

special instructions

According to the instructions, inside Vinpocetine should be taken with caution with angina, arrhythmias, low vascular tone and unstable blood pressure.

As a rule, parenterally the drug is used in acute cases, and, after improving the clinical picture, switch to the form of tablets.

In the treatment of chronic diseases, the drug should be taken orally.

Drug interaction

The simultaneous use of vinpocetine and methyldopa sometimes caused some enhancement of the hypotensive effect, therefore, such treatment requires regular monitoring of blood pressure. Increases the risk of hemorrhagic complications on the background of heparin therapy.

No interaction was observed with simultaneous use with beta-blockers (chloranolol, pindolol), clopamide, glibenclamide, digoxin, acenocoumarol and hydrochlorothiazide, imipramine.

Analogues of Vinpocetine Drugs

The structure determines the analogs:

  1. Cavinton Forte.
  2. Telektol.
  3. Vinpocetine Acre (ESCOM, AKOS).
  4. Vincentin
  5. Vinpocetine Forte.
  6. Vinpoton.
  7. Bravinton
  8. Cavinton
  9. Vero-Vinpocetine.

Vinpocetine medicine

Patients with circulatory disorders of the brain often complain of fatigue, migraine, problems with pressure, lack of energy. Vinpocetine is a medicine that stimulates blood circulation in the brain. Tablets and injection are prescribed to patients after angiography or tomography. In case of critical circulatory disorders of the brain, the medicament is taken in courses of 2 months 2-3 times a year.

Composition and release form

The drug Vinpocetine produced in the form of tablets and solution for injection. The main active ingredient of the drug is vinpocetine, obtained by mixing vincamine and the periwinkle small alkaloid. Magnesium stearate is added to the tablets to stabilize the active substance. Solution for injection includes ascorbic acid, sodium metabisulfite, tartaric acid, which enhance the positive effect of the drug. The table contains the full composition of the two forms of release of the drug.

Concentration in mg

Magnesium stearate, talc, corn starch, lactose, silicon dioxide


Ascorbic acid, sodium metabisulfite, tartaric acid, benzyl alcohol, sorbitol, water for injection.

Pharmacodynamics and pharmacokinetics

The drug improves blood circulation in the brain's blood vessels, stimulates metabolism and has a positive effect on the rheological properties of the blood. The neuroprotective effect is realized by blocking excitatory amino acids. The instructions for use say that the substance improves brain metabolism. Thanks to this drug, glucose and oxygen consumption increases, inertness to hypoxia increases. The exchange of serotonin and norepinephrine in the brain is growing.

The drug has a vasodilating effect on cerebral vessels, which leads to a decrease in pathological blood viscosity. The tool improves glucose metabolism and may slightly lower blood pressure. According to the instructions, the substance is absorbed within 1 hour after ingestion. Cleavage is mostly carried out by the proximal intestinal tract. The active substance easily penetrates histohematogenous barriers.

Indications for use

The tool is prescribed for chronic and acquired vascular diseases of the brain. The solution is prescribed for acute forms of disease. According to the instructions means improves cerebral blood flow. In some cases, it is considered rational to use drugs for the treatment of cerebral stroke. Indications for use of the drug are as follows:

  • vascular diseases of the retina and shell of the eye,
  • secondary glaucoma,
  • degenerative changes in the macula,
  • age-related or medication-induced hearing loss,
  • neurological manifestations of menopausal syndrome,
  • chronic forms of circulatory insufficiency of the brain (different types of encephalopathy, dementia, transient ischemic attacks, etc.).

Dosing and Administration

For long-term improvement of cerebral circulation take 1 tablet 3 times / day for 2 months. Before the abolition of the drug dose should be gradually reduced. Capsules are taken after meals and washed down with plenty of water. The initial dosage of the solution for injection is 20 mg per 1 liter of saline. Gradually, the dose is increased to 1 mg per 1 kg of the patient’s body weight. The course of treatment is 14 days.

This form of the drug is considered more convenient to take. The instructions for use say that 1 tablet contains 5 mg of active ingredient. Capsules take a long time to achieve a lasting improvement in the blood supply to the brain. It is not recommended to drink pills on an empty stomach, because magnesium stearate will come into contact with undiluted hydrochloric acid, causing nausea and vomiting.

Vinpocetine Acre

The main difference of this form of the drug from the classic is the presence of aerosil in the composition of the tablets. This substance enhances the absorption of the drug. The bioavailability of the drug, based on the instructions for use, will be higher than that of the usual drug. In order to avoid hemorrhagic complications, the medicine is not taken together with anticoagulants after a stroke.

Solution for injection has a more saturated composition. It contains ascorbic acid, which increases the tone of cerebral vessels. Tartaric acid is a natural antioxidant that promotes the splitting of excess platelets. Vinpocetine is prescribed in ampoules if a patient has acute circulatory disorders. Long-term use of this form of the drug increases the risk of bleeding. Concentrate for infusion diluted on the basis of the recommendations of the instructions for use.

During pregnancy

The active ingredient penetrates the placental barrier, so the drug is not used during gestation and breastfeeding. When ingested, the drug is distributed through the blood to all organs. If a woman takes 2-3 tablets at the same time, then placental bleeding and spontaneous abortion may occur, the cause of which will be increased placental blood supply.

In childhood

The instructions for use of Vinpocetine said that it is impossible to give it to persons under 18 years of age. To date, no studies have been conducted confirming the safety of the drug for the fragile and developing organism. The drug can be used to treat vegetative-vascular dystonia or increased intracranial pressure in a child, but only after consulting a specialist.

Vinpocetine and Alcohol

The side effect of the drug is similar to the effect that alcohol has on the body. At the same time taking Vinpocetine and alcoholic beverages, people develop heavy sweating. A person may begin tachycardia. The drug improves blood circulation, so the decay products of ethanol quickly reach the brain, which provokes a strong migraine. When taking alcohol and this drug at the same time, a person may experience the following side effects:

  • nausea and vomiting
  • deterioration of visual acuity
  • a sharp drop in blood pressure,
  • hearing problems and heart work,
  • increased sleepiness.


The mechanism of action of vinpocetine consists of several elements: it improves cerebral blood flow and metabolism, has a beneficial effect on the rheological properties of blood.

The neuroprotective effect is realized by reducing the adverse cytotoxic effect of excitatory amino acids. Blocks Na + and Ca 2+ channels and NMDA and AMPA receptors. Vinpocetine stimulates metabolism in the brain: it increases the absorption and consumption of glucose and oxygen. Increases tolerance to hypoxia, increases glucose transport, the only source of energy for brain tissue, through the BBB, shifts glucose metabolism towards an energetically more favorable aerobic pathway. Selectively inhibits Ca 2+ -calmodulin-dependent cGMP-PDE. It increases the metabolism of serotonin and norepinephrine in the brain, stimulates the noradrenergic neurotransmitter system and has an antioxidant effect.

It improves microcirculation in the brain by inhibiting platelet aggregation, reducing pathologically increased blood viscosity, increasing red blood cell deformability and inhibiting adenosine reuptake, promotes the transfer of oxygen into cells by reducing red blood cell affinity for it. Selectively increases cerebral blood flow by reducing cerebral vascular resistance without significantly affecting the systemic blood circulation parameters (BP, cardiac output, heart rate, OPSS), does not cause a “steal” effect.

Vinpocetine is rapidly absorbed after ingestion, Tmax is achieved after 1 h. Absorption occurs mainly in the proximal intestine. Not metabolized when passing through the intestinal wall. Easily penetrates histohematogenous barriers (including BBB).

In preclinical studies of the administration of radioactively labeled Vinpocetin inside it was determined in the highest concentrations in the liver and gastrointestinal tract. Cmax in tissues observed 2-4 hours after ingestion.

The amount of radioactive isotope in the brain did not exceed that in the blood. Communication with proteins in the human body - 66%. Vd is 88.5 liters, indicating a significant binding to the tissues. When administered parenterally Vd - 5.3 l / kg. Bioavailability by ingestion - 7%. Clearance is 66.7% and indicates extrahepatic metabolism.

With repeated ingestion of doses of 5 and 10 mg, the kinetics is linear, with Css plasma levels were (1.2 ± 0.27) and (2.1 ± 0.33) ng / ml, respectively. T1/2 in humans it is (4.83 ± 1.29) hours. In studies with radioactively labeled vinpocetine, it was found that the main ways of elimination are kidney excretion through the intestine in a 3: 2 ratio. In preclinical studies, the highest radioactivity was determined in bile, however, no evidence of significant enterohepatic circulation was found.

The main metabolite of vinpocetine is apovincaminic acid (AVK), whose share in humans is 25–30%. After taking Vinpocetine inside the AUC AVK is 2 times greater than that after iv administration. This suggests that AVK is formed in the process of metabolism during the first passage of Vinpocetine. AVK is excreted by the kidneys by simple glomerular filtration, T1/2 depends on the dose taken and the route of administration of vinpocetine. Other known metabolites are hydroxyquinpocetin, hydroxy-AVK, dihydroxy-AVK-glycinate, as well as their conjugates with glucuronides and / or sulphates. In unchanged form, vinpocetine is released in a small amount.

Special patient groups

Due to the lack of cumulation due to the nature of the metabolism, there is no need for dose adjustment for liver and kidney diseases.

The pharmacokinetics of vinpocetine in elderly patients is not significantly different from that in young patients, cumulation of vinpocetine is absent. Therefore, Vinpocetine can be prescribed for elderly patients with impaired liver and kidney function for a long time and in usual doses.

Use of Vinpocetine

Violation of cerebral circulation (includingstroke, vertebro-basilar insufficiency, brain injury, atherosclerotic changes in brain vessels, vascular dementia, hypertensive and post-traumatic encephalopathy), intermittent insufficiency and vasospasm of the brain, partial occlusion of arteries, headache, dizziness (occlusion of arteries, partial occlusion of arteries, headache, dizziness) , memory impairment, movement disorders, including apraxia, aphasia, arteriolosclerotic and angiospastic changes of the retina and choroid, arterial and venous vascular thrombosis of the eye vessels, degenerative changes in the yellow spot, secondary glaucoma due to obstruction of the vessels, age, vascular or toxic (medical) hearing impairment, H. in ears, vasovegetative manifestations of menopausal syndrome (in combination with hormone therapy).

Use during pregnancy and lactation

Vinpocetine penetrates GPB and is therefore contraindicated in pregnancy. Moreover, its concentration in the placenta and in the blood of the fetus is lower than in the blood of the pregnant. At high doses, placental bleeding and spontaneous abortions are possible, probably as a result of an increase in placental blood supply.

Within 1 hour, 0.25% of the dose of vinpocetine penetrates into breast milk. When using Vinpocetine, breastfeeding should be stopped.

Indications for use Vinpocetina

What is Vinpocetine prescribed for? The therapeutic properties of the tablets have been described above. In therapeutic practice, Vinpocetine is used to treat the following conditions and pathologies:

  • treatment of various forms of cerebrovascular disease,
  • treatment of perceptual senile hearing loss, Meniere's disease and tinnitus,
  • vertigo labyrinth genesis, cochleovestibular neuritis,
  • ischemic transient attack, stroke,
  • traumatic brain injuries,
  • with encephalopathy of various origin,
  • atherosclerosis of cerebral vessels, dementia,
  • in the post-stroke period.

In order to avoid complications, apply strictly as prescribed by a doctor.

Instructions for use Vinpocetine dosage

How to take vinpocetine before or after a meal? The instructions for use are recommended after meals with plenty of water.

The initial dosage of Vinpocetine tablets is usually 15 mg per day, taken in the morning after a meal, without chewing or grinding.

Further therapy is determined individually, depending on the diagnostic indicators and the response of the body.

The maximum dose of the active substance per day is about 30 mg (depending on body weight).

The standard course of therapy, according to the instructions for use, provides a course with a dosage of 15-30 mg (5-10 mg 3 times daily after meals) for a duration of 90 days. Stable effect from taking the drug will be noticeable after 7 days.

Up to 30 mg dosage increase only when necessary.

At the end of therapy, reduce the dosage gradually, in order to avoid the "effect of cancellation."

A dosage of 30-45 mg can contribute to the formation of memory in healthy people, but it is more likely isolated cases.

Be wary of prescribing to patients with a Q – T interval extension. In hemorrhagic stroke, the introduction of the product can not be started earlier than 5-7 days.

Increases the risk of hemorrhagic complications on the background of heparin therapy. Strengthens the action of antihypertensive drugs.

In case of impaired liver or kidney function, you can use the usual doses of the drug.

Vinpocetine is suitable for long-term use, as it does not accumulate in the body.

How to take vinpocetine children up to a year? In pediatrics, the drug has not been properly tested and is not recommended for use in children under one year old.

Analogues of Vinpocetine, a list

Similar substances in the active substance:

If you want to replace it with an analog, you must consult a doctor, you may need a dosage adjustment or treatment regimen.

Important - Vinpocetine instructions for use, price and reviews below have no relation to analogues and cannot be used as a guide or instruction. Any replacement of the drug should be under the supervision of the attending physician.

Which is better, Vinpocetine 10 or 20? This is one and the same drug in different dosages. It is more convenient to use the one that is prescribed for treatment in a single dose.

Features of the use of Vinpocetine in the form of tablets

The mechanism of action of Vinpocetine is aimed at improving blood circulation in the brain, as well as providing a positive effect on the body's metabolism.

Pharmacokinetics of the drug is the rapid absorption from the gastrointestinal tract and the absorption of the active components in the intestine through histohematogenous barriers and tissues.

The purpose of treatment with Vinpocentimo in the form of tablets is the most convenient method of therapy.

Start taking pills 5 mg 3 times a day. Further, the dose is increased to 2 tablets 5 mg - 3 times a day. In the main period of treatment must be taken before 20 mg of drug for 1 reception. The dosage should be gradually increased to match the body weight (1 mg of the drug per 1 kg of the body).

Before withdrawal of treatment, the dosage should also be gradually reduced.

Treatment courses can be carried out 2-3 times a year.

Features of the use of ampoules Vinpocetina

The use of Vinpocetine injections is an alternative to taking 10 mg tablets. The preparation solution contains a number of auxiliary acids and alcohols.

Rules for the appointment of a solution in ampoules: start the course with 20 mg and is brought to the figure corresponding to the weight of the patient. The solution is injected both intramuscularly in the form of injections, and intravenously in the form of droppers 1 time per day. The course of treatment is 10-14 days.

Vinpocetine solution for use in the form of droppers should be diluted with saline or 5% glucose solution.

In the event of side effects, the maximum dose should be left at the level of 50 mg/day.

Appointment of Vinpocetine to children

Vinpocetine is contraindicated in the children's return, but in a number of diseases the doctor may be prescribed a course of drug treatment. The drug is prescribed for vegetative dystonia and increased intracranial pressure in a child. In such cases, reduce the dosage of the drug, and it is 1/3 or 1/4 adult dosage 3-4 times a day after meals, drinking plenty of water.

Compatibility Vinpocetine with alcohol

In connection with the therapeutic effect and indications for the use of Vinpocetine, among which are diseases of the brain, stroke, dementia, the use of alcohol during treatment is prohibited. Drinking alcohol during the course of treatment can lead to such side effects as:

  • the occurrence of nausea and vomiting,
  • blurred vision
  • a sharp drop in pressure
  • hearing and heart problems

Analogues of Vinpocetine

Vinpocetine has a number of analogues that have a similar therapeutic effect and affordability.

Vinpocetine substitute drugs include:

  1. Vinpocetine Forte, Vinpocetine Forte Canon, Vinpocetine-Ros,
  2. Cavinton,
  3. Piracetam,
  4. Etc.

Analogues of Vinpocetine are similar in composition, and, accordingly, to achieve a therapeutic effect. At the same time, the analogues have some differences from Vinpocetine, which consist both in the conditions of administration, the duration of the course of treatment, and the presence of contraindications.

Therefore, it should be noted that the use of Vinpocetine analogue must be coordinated with the attending physician, who will assess the feasibility and safety of taking the drug.

Application Vinpocetina Forte

Vinpocetine Forte tablets are equivalent in effect to Vinpocetine 10 mg tablets. A special feature of Vinpocetine Forte is that it has a number of auxiliary components that have a more pronounced treatment effect. Also, the difference is that the treatment with Vinpocetine Forte is longer, the duration of which can reach 3 months.

Rules of application: at the first stage, tablets are used 20-30 days, 5-10 mg - 3 times a day, at the second stage - 50-60 days - 5 mg 3 times a day.

Comparison of Vinpocetine and Piracetam

When choosing one or another analogue, the patient's history is evaluated. Despite the similarity in the composition of these drugs there is a significant difference in the appointment. Detailed information can be found in the annotations to the drugs. However, recent studies have shown the effectiveness of the use of Vinpocetine and Piracetam in the complex. It is important to note that only the attending physician can recommend the use of these drugs at the same time.

It is worth noting that Piracetam is relatively cheaper than Vinpocetine due to the difference in the countries-producers.

Comparison of Vinpocetine and Cavinton

The composition of both drugs contains the active ingredient - Vinpocetine, so the mechanism of action of drugs is almost the same, despite the insignificant differences that can be found in a detailed study of the annotations of drugs.

The important difference between drugs is price. Caviton is several times higher than Vinpocetine due to the difference in manufacturers and place of production.

But It is worth noting that when prescribing the drug, specialists make a choice in favor of Caviton, since it is believed that it is better tolerated. Moreover, it is produced by a reputable import manufacturer, while Vinpocetine is produced by small pharmaceutical companies and its quality may be in doubt.

Please note that not all analogs of Vinpocetine are easily found in pharmacies. Before buying an analogue, it is necessary to monitor pharmacy chains for the sale of a particular drug.

It is important to note that there are many drugs on the Internet with similar indications, but one should not rely on the patient reviews that are presented to them, since there is a risk of being taken by an unscrupulous manufacturer. When choosing analogues it is always necessary to familiarize yourself with the instructions, indications for use, contraindications, as well as side effects.

Price Vinpocetine

The cost of the drug depends on the form of release, the pharmacy chain that implements Vinpocetine, from the city in which the medicine is purchased:

  • in ampoules (10 pcs., 0.5%, 2 ml) - average price - 50-60 rubles,
  • in tablets - 10 mg - 30 pieces, 5 mg - 50 pieces. - 50-130 rubles.


Thus, Vinpocetine is the best option for the treatment of problems of cerebral circulation, because it has several advantages compared with a group of analogues. These include: optimal pricing, availability of the drug, convenient forms of taking the medicine, a large number of positive feedback from patients.

What does Vinpocetine treat?

The drug is used in various fields of medicine:

  1. Neurology: in chronic forms of circulatory disorders, dementia, cerebral stroke, vascular atherosclerosis, post-traumatic and hypertensive encephalopathy, vertebrobasilar insufficiency. Also, the drug is used: traumatic brain injury, impaired memory and attention, severe headaches, dizziness, movement disorders in atherosclerosis, hemorrhage and cerebral infarction.
  2. Ophthalmology: in chronic diseases of the eye membranes, in particular the retina, the presence of secondary glaucoma.
  3. Otology: with a decrease in hearing of various etiologies, vascular diseases of the ear.
  4. Gynecology, endocrinology: menopause and menopause in women.

High effective functions of the drug were noted. The use of Vinpocetine reduces platelet sticking, improves viscosity, fluidity, blood, increases the transfer of oxygen to the blood cells of the whole organism. Absorption and utilization of glucose increases. Strengthens the general condition of the body, it is recommended for older people.

Use and dosage

Available in tablets and capsules with solutions for injection. Vinpocetine tablets taken orally, after or during meals, one 3 times a day. Daily dose of the drug - 15-30 mg. The treatment lasts about three months.

In acute periods of disease, intravenous administration of the drug is recommended. First, use 20 mg of the drug, which is dissolved in a liter of infusion solution. After 10 days - two weeks, after the patient's condition improves, the treatment is continued with tablets (5-10mg per day). Depending on age and disease, the dosage of the drug may vary.

Can not be applied

Contraindications Vinpocetine:

  • children under 18 years old
  • pregnant women and nursing mothers,
  • patients with severe coronary artery disease,
  • people with increased intracranial pressure,
  • patients with severe arrhythmia,
  • patients with hypersensitivity to the active substance.

Before using the drug, be sure to read the instructions, as possible adverse reactions.

It is important to know! If side effects such as fever, nausea, weakness, feeling of heaviness in the abdomen, dryness of the oral mucosa, flushing of the skin on the face, decrease in pressure appear when using the medication, consult a doctor immediately!

Less common may occur:

  • eating disorders (loss of appetite, diabetes),
  • mental disorders (poor sleep, feeling of fear),
  • malfunction of the organs of hearing (tinnitus),
  • violations of the gastrointestinal tract (diarrhea, delayed stool, etc.),
  • on the part of the cardiovascular system (ischemia, myocardial infarction, cardiac arrhythmias - increase and decrease, hypotension),
  • various damage to the skin (itching, rash).

Features of use. In the case of the appointment of the drug to elderly patients, it should be remembered that this drug produces a large percentage of adverse reactions in these people.

Recommendation! Special instructions: it is strictly forbidden to consume alcoholic beverages.

Newborns and children under 18 years of age do not recommend Vinpocetine. Obviously its negative impact on the child's body. However, specific research data has not yet been obtained, since no tests were conducted on children. Nevertheless, many neurologists recommend this drug to infants, after carefully conducted research and test results. As an exception, prescribed in cases of perinatal pathology of the nervous system, to restore hearing, with its sharp decline, for the treatment of eye diseases, epilepsy.

With brain concussion, taking Vinpocetine improves the activity of the nervous system, provokes the production of serotonin (this makes emotions brighter), is combined with Piracetam, is an antidepressant.

Release form Vinpocetine, product packaging and composition.

1 tab.
5 mg

25 pcs. - Contour cell packages (1) - cardboard packs.
25 pcs. - Contour cell packages (2) - cardboard packs.

All the above information is presented only for familiarization with the drug, the possibility of the use should be consulted with the doctor.

A means of improving cerebral circulation and brain metabolism. Inhibits phosphodiesterase activity, which contributes to the accumulation of cAMP in tissues. It has a vasodilating effect mainly on the vessels of the brain, which is caused by direct myotropic antispasmodic action. Systemic blood pressure drops slightly. It improves blood flow and microcirculation in the brain tissues, reduces platelet aggregation, and contributes to the normalization of the rheological properties of blood. It improves the portability of hypoxia by brain cells, facilitating the transport of oxygen to tissues due to a decrease in the red blood cell affinity for it, enhancing the absorption and metabolism of glucose. Increases the content of catecholamines in brain tissue.

Special instructions for use Vinpocetine.

With caution used internally for arrhythmias, angina, with unstable blood pressure and low vascular tone. Parenteral, as a rule, is used in acute cases to improve the clinical picture, then move to oral administration. In chronic diseases, Vinpocetine is taken orally. In hemorrhagic cerebral stroke, parenteral administration of vinpocetine is allowed only after the reduction of acute events (usually 5-7 days).