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Can I take diphenhydramine for allergies?


Diphenhydramine (diphenhydramine) is a domestic drug used in medicine for over 50 years. Diphenhydramine is most commonly used as it blocks the production of histamines in the patient’s body, preventing the development of allergic symptoms.

Despite the fact that this drug belongs to the first generation of anti-allergic drugs and has some side effects, it is still in demand in medical practice for allergies.

Its demand, first of all, is connected with availability in a price category. In 2012, according to the WHO recommendation, Dimedrol was again added to the list of essential medicines. Currently, the drug is most often used in inpatient treatment to relieve allergies. In addition, it can be actively used to relieve pain and high body temperature. In this case, the drug is combined with a 50% solution of analgin and 2% solution of papaverine hydrochloride.

pharmachologic effect

Diphenhydramine is able to enhance the effect of alcohol (ethanol) and certain drugs acting on the nerve endings. The drug may decrease the efficacy of some emetic medications. For example - apomorphine, used to treat toxic poisoning.

Diphenhydramine blocks histamine receptors (H1), thereby blocking severe allergic manifestations. In addition, it is able to prevent spastic processes in smooth muscles, reduce vascular permeability, eliminate hyperemia, swelling and itching.

Dimedrol has a local analgesic effect. When it is used, there is a slight decrease in blood pressure and a sedative effect.

The maximum accumulation of the drug in the blood during allergies is achieved after 1 hour. Duration of medicinal action is from 4 to 6 hours. Metabolic processes occur in the liver. The active substance (diphenhydramine) can penetrate into the brain tissue, the placenta and breast milk.

Indications for use

The following manifestations can serve as indications for the use of Dimedrol:

  • vasomotor rhinitis, allergic conjunctivitis,
  • acute development of iridocyclitis, pollinosis, urticaria,
  • any manifestations of allergies to dermatitis and dermatosis,
  • the development of angioedema (Quincke), capillary toxicosis,
  • development of an asthmatic attack with bronchitis,
  • radiation sickness, anaphylactic shock,
  • Parkinson's disease, hemorrhagic vasculitis.

In addition, Dimedrol is actively used in preparation for surgery as a premedication (reduction of anxiety and anxiety in a patient).


The use of Dimedrol is not recommended:

  • with increased individual sensitivity to the drug,
  • do not use Dimedrol in angle-closure glaucoma, epilepsy,
  • prostatic hyperplasia, cervical stenosis in the bladder,
  • peptic ulcer of the stomach complicated by stenosis
  • children up to 7 months.

In addition, with caution prescribed medication for allergies during pregnancy.

special instructions

In the first two trimesters of pregnancy, the drug is strictly prohibited, since it can cause an abortion. At the beginning of the third semester, when it is impossible to carry out another therapy, tablets of Dimedrol can be used no more than twice.

Diphenhydramine during pregnancy has a positive effect for six hours. The drug is completely removed from the woman’s body in 24 hours. The side effects of this drug in this difficult period for a woman are manifested by weakness, trembling of the extremities, and increased fatigue. There may also be a sharp drop in blood pressure, tachycardia, the appearance of seizures. The most dangerous complication may be the negative impact of the drug on the baby and preterm labor.

However, Dimedrol has a number of positive points: sedative effect, hypnotic, antihistamine. Very often the drug is used in combination with analgin for relieving painful contractions in the case of incomplete opening of the uterus. In addition, diphenhydramine actively relieves allergic bronchospasm.

When treating Dimedrol, it is necessary to exclude the driving of any vehicles and labor activity, which requires special care and a quick psychomotor reaction.

In case of allergy, Diphenhydramine is not recommended to be injected subcutaneously, due to the risk of abscesses, and ultraviolet radiation and interaction with ethanol should be avoided.

Drug action

Means Dimedrol has a complex effect, so it can be used at all stages of the manifestation of an allergic reaction. It quickly suppresses the histamine jump in the human body, and unpleasant symptoms are instantly removed, regardless of their severity.

The drug is released in pill form and after taking it, the person immediately feels a significant relief. Swelling of the soft tissue is reduced, itching disappears, passing the remaining signs indicating an allergy. Even if there is angioedema, which is dangerous due to its consequences, diphenhydramine from allergies can effectively cope in this situation. And all because this medicine has the following effect:

  • anti-inflammatory,
  • antispasmodic,
  • anesthetic,
  • antiemetic,
  • antiallergic,
  • antipruritic
  • ganglioblokiruyuschee.

Not every drug can boast of such an extensive effect.

Indications and contraindications

The drug Dimedrol for allergies is indicated in the following cases:

  1. if, against the background of such a reaction, Meniere's syndrome occurs,
  2. in the formation of the development of conjunctivitis and runny nose,
  3. when soft tissues swell,
  4. with allergic dermatitis, which are accompanied by intolerable itching and extensive rashes,
  5. when it comes to pollinosis and hemorrhagic vasculitis,
  6. in the presence of serum sickness.

Moreover, this medicine has a positive effect in insomnia and neurosis. But, despite the large number of useful properties, the drug Dimedrol has its own contraindications. It cannot be used in the following cases:

  • When chronic gastric diseases or intestinal ulcers become acute.
  • With the body intolerance to the components contained in the composition of this tool.
  • If a person suffers from angle-closure glaucoma.
  • With bronchospasm, epilepsy and bronchial asthma.
  • When there are serious irregularities in the urogenital system and the person is experiencing problems urinating.
  • With existing dysfunctions of the prostate gland.

As for side effects, they can manifest themselves with an overdose of the drug. Then there are convulsions, some internal organs begin to work worse and cease to cope with their main tasks, consciousness becomes confused. Drowsiness appears, the pressure is greatly reduced, problems with coordination of movements may begin. In women, sometimes there are failures of the menstrual cycle, increased nervousness. Some patients while taking Dimedrol complain of a decrease in the clarity and quality of vision, on photophobia, on violations in relation to taste buds.

Rules for taking this medicine

It is better to take the drug Dimedrol according to the recommendation of the doctor, who determines the daily dosage and frequency of doses based on the patient’s general condition and age. This medicine is allowed to use to combat allergies to children over 12 years old.

Adults are usually recommended to use one tablet once a day, washing it down with a sufficient amount of water. If the drug is prescribed with a minimum concentration of an active substance such as diphenhydramine, then it should be drunk three times a day. The duration of the entire treatment course is usually two weeks.

In addition to tablets, diphenhydramine can be used in ampoules for allergies, which occurs as a side reaction to the use of certain medications. In this case, histamine concentration in the blood decreases rapidly. Especially effective this type of medicine for dermatosis, urticaria, pollinosis and vasomotor rhinitis. Introduced this tool intramuscularly or intravenously.

With extreme caution, Dimedrol in ampoules is prescribed to elderly people, and also if a person has problems with blood vessels and the heart. With hyperthyroidism and increased intraocular pressure, allergy shots are also not recommended.

During treatment, you should exclude the use of alcoholic beverages. Otherwise, you can provoke unwanted reactions from the body. Do not immediately after taking the drug to get behind the wheel or perform actions that require special concentration of attention. But, despite such negative moments, Dimedrol is considered one of the most effective and effective drugs for allergies.

Composition and forms of release

Diphenhydramine is produced in various forms. Among them:

  • tablets (50 mg of active ingredient),
  • injection solution (10 mg of active ingredient per 1 ml of water),
  • ointment, gel (1-2%),
  • rectal suppositories (5-20 mg).

Each medicine consists of the active substance - diphenhydramine, as well as formative components, which do not produce any effect on the body.

There are also eye drops for allergies with Dimedrol, which is part of the drug as one of the ingredients (for example, Polynadim or Dinaf is a combination of Dimedrol and Naphthyzinum).

According to the doctor’s prescription at the pharmacy, Dipedrol-zinc paste or drops in the eye can be prepared (0.2-0.5% solution in 2% boric acid solution).

Indications for use Dimedrol from allergies

Diphenhydramine is used for a wide variety of diseases and conditions.

Diphenhydramine is quite common in other medicines.

It may be food allergiesmanifested by swelling of the mucous membranes (with a strong swelling of the face, a feeling of distention from the inside, an ambulance must be called)

Skin allergy, developed for a variety of reasons, including urticaria and dermatosis, accompanied by itching. In this case, tablets or injection are used, they are also used for allergic rhinitis and pollinosis, allergic reactions to medications.

With allergic conjunctivitis and iridocyclitis eye drops are applied. Gel with Dimedrol for allergy is used for sunburns I degree, photodermatosis, insect bites, any skin manifestations of allergy, accompanied by itching.

Apply also ointment with Dimedrol against allergies in the form of contact dermatitis.

This drug has many indications of a non-allergic nature (including the already mentioned premedication, radiation sickness, peptic ulcer, Parkinson's disease, vomiting, including in pregnant women, etc.) - as part of complex therapy.

A well-known combination - diphenhydramine with analginum - is not used for allergies. It is used in the case when it is necessary to strengthen the antipyretic and analgesic effects of dipyrone by the sedative effect of Dimedrol (for example, during high fever).

Therefore, the question of what prick for diphenhydramine from allergies is relevant only if the allergic reaction is accompanied by a rise in temperature.

Standard Adult Dosages

In cases of severe allergies (for example, angioedema, as well as secondary measures in the treatment of anaphylactic shock) Dimedrol is administered intravenously slowly 2-5 ml of 1% solution in 100 ml of saline (such measures are carried out only by a medical worker or during transportation).

Reviews on the use of Dimedrol from allergies - only for the night, strongly tend to sleep

Dimedrol is administered intramuscularly, 1-5 ml of 1% solution. Often, people have a question: how to prick diphenhydrol with allergies? The answer is simple: strictly prescribed by a doctor.

The maximum single dose for intramuscular injection - 50 mg, daily - 150 mg, i.e. at most one day you can put three injections of 50 mg, but without a doctor's prescription it is better not to do this.

Inside take 10-50 mg 1-3 times a day (but no more than 100 mg at a time, 250 mg a day). On the Internet there is a question: can I take Diphenhydramine in ampoules with allergies? In principle, yes, because the injection solution does not contain any substances hazardous to the digestive tract, and the tablets do not contain any additional active ingredients.

If you drink diphenhydramine in ampoules - allergies will pass faster? The concentration of the main substance in the tablets is higher, in addition, it is in any case the same drug, therefore - no.

Other uses

  1. Eye drops instilled into each conjunctival sac three times a day, using a 0.2-0.5% solution in a 2% solution of boric acid.
  2. Local allergy medications with Dimedrol, i.e. gels, ointments and creams are applied to the itchy and inflamed areas with a thin layer 3-4 times a day.
  3. In the case of allergic rhinitis use a special form of release - sticks with Dimedrol, each with 50 mg of the active ingredient. They are administered intranasally.

The course of allergy treatment with Dimedrol depends, again, on the age of the patient, the severity of the disease, as well as the form of release of the drug and averages from 7 to 15 days. It must be remembered that if the treatment is started independently, if it is ineffective within 7-10 days, it is necessary to consult a doctor.

The dose of Dimedrol for children with allergies is different from that in adults. This is due not only to the lower weight of the child, the immaturity of the digestive tract and a higher susceptibility to any medication, but also to the high risk that Allergy to Diphenol will develop.

In this regard, it is necessary to immediately clarify some issues:

Yes, maybe, like any other drug. Moreover, an adult can also "give out" an allergic reaction to this remedy, only the probability of this is lower.

Allergy to Dimedrol, like any drug allergy, can manifest itself in several ways:

  • alimentary (nausea, vomiting, diarrhea, abdominal pain),
  • skin (allergic rash with itching and peeling of the skin, urticaria),
  • angioedema, angioedema,
  • anaphylactic shock,
  • photosensitization.

That is, if you developed an allergy to diphenhydramine - the symptoms will differ little from an allergy to any other drug.

In the studies presented in the medical journal "The attending physician" concerning the calls of ambulance teams as a result of drug allergy, the statistics of allergic reactions to certain drugs are presented.

The most allergenic are NSAIDs and analgesics (analgin, aspirin), as well as antibiotics. Several more groups of drugs cause allergies more often than others. 33% of all calls were made as a result of single cases of drug allergies, including mucolytics (4), diuretics (4), hormonal drugs. Allergies to antihistamines developed only in two cases, and these were Pilpofen and Klaratodin.

More reliable studies have not been conducted, and in the instructions for use the frequency of allergic reactions is not spelled out. Based on these facts, we can conclude that allergy to diphenhydramine is a very rare phenomenon.

Instructions for use and dosage

In each box of pills is an abstract to the drug. The daily dosage and frequency of administration is determined by the doctor. taking into account the condition of the patient. The doctor also suggests the optimal duration of the therapeutic course. It is forbidden to violate the rules of admission, independently adjust the dosage.


  • take the pill inside, chew the drug can not
  • a sufficient amount of water will help speed up the passage of Dimedrol through the esophagus,
  • the dosage for adults is 1 tablet, the frequency of administration is 1 to 3 times a day (the concentration of diphenhydramine is 0.03 or 0.05 g),
  • as a sleeping pill, 1 tablet is recommended just before bedtime (the content of the active substance is 0.05 g),
  • antiallergic medicine with a sedative effect to take no more than 14 days,
  • a drug based on diphenhydramine hydrochloride is allowed for patients over 12 years old,
  • the absence of noticeable relief from the course of allergic diseases is a reason for a visit to the doctor. With a low efficacy of the drug, the doctor will select another drug.

Side effects

Diphenhydramine is an antihistamine with a sedative effect on the body. During therapy, some patients complain of negative reactions. Tablets antiallergic drug of classical action are more likely to cause negative manifestations than modern formulations.

In case of overdose, the negative symptoms increase, the condition worsens quickly, especially in childhood. There are dangerous phenomena: convulsions, confusion, problems with the functioning of organs. Failure to help may end badly.

Learn about the symptoms of dust allergies and pathology treatments.

About the causes and treatment of allergic microbial eczema on the feet is written in this article.

Перейдите по ссылке и прочтите о правилах и способах применения мумиё для лечения аллергических заболеваний.

Possible side effects:

  • apathy, malaise, drowsiness,
  • decrease in blood pressure, negative effects on the cardiovascular system,
  • painful urination
  • tremor of the upper limbs,
  • dizziness,
  • problems with coordination of movements,
  • failures in the menstrual cycle
  • bronchospasm, nasal congestion, discomfort in the chest area,
  • urticaria, rash on different parts of the body, swelling of the mucous bronchi,
  • irritability, nervousness,
  • dry mouth, diarrhea or constipation, nausea, flatulence, abdominal pain, impaired taste receptor sensitivity,
  • convulsions
  • reduced quality of vision
  • photophobia, excessive sweating, patient chills,
  • confusion

Storage conditions


  • the room is dry, with a temperature of +15 С… + 25 С,
  • children should not have access to a blister with pills,
  • Diphenol is 48 months old,
  • expired medication is prohibited.

For the relief of allergy symptoms, it is difficult to find a drug at the same low cost as Diphenhydramine tablets. The average price of Dimedrol is not higher than 8–10 rubles.

Diphenhydramine injections

Composition, action, application:

  • the active component of the anti-allergic agent, diphenhydramine, 1 ml of the medicinal solution contains 10 mg of the active substance,
  • sedative, antihistamine, hypnotic effect,
  • treatment of diseases of an allergic nature, including a negative response to the use of medicines of various groups,
  • Diphenhydraz in ampoules quickly blocks receptors responsible for the immune response, reduces the concentration of histamine in the blood,
  • the drug is effective in the treatment of urticaria, vasomotor rhinitis, dermatosis (eliminates severe itching with allergies, redness), allergic conjunctivitis, pollinosis,
  • the drug in the form of injections is prescribed for problems with sleep, as a sedative composition,
  • the route of administration is intravenous or intramuscular. Subcutaneous administration is excluded (diphenhydramine exhibits an irritant effect),
  • the average daily dosage for adults: intravenous - from 20 to 50 mg dimedrol + from 75 to 100 ml of isotonic solution (component - sodium chloride). Intramuscular injection of 10 to 50 mg of dimedrol (from 1 to 5 ml of a solution of 1%),
  • with caution Dimedrol in injections is prescribed to elderly patients, with severe diseases of the heart and blood vessels, with high levels of intraocular pressure, hyperthyroidism,
  • the combination of antihistamine and alcohol during therapy is excluded,
  • noticeable sedation, drowsiness after the administration of the medicinal solution - signs that adversely affect the speed of psychomotor reactions. While receiving injections of Dimedrol, you should not drive motor vehicles or perform actions associated with complex mechanisms,
  • antihistamine injections are allowed for children after 12 years,
  • The average cost of antiallergic, hypnotic, sedatives is suitable for all patients: 20 rubles for 10 ampoules.

Despite the emergence of effective and safe antihistamine formulations of new generations, doctors use Dipedrol until now, when it is necessary to actively influence histamine receptors. Tablets and shots on the basis of diphenhydramine hydrochloride quickly remove the pronounced swelling, calm the patient, prevent panic, depression, overexcitement, often developing with severe allergic reactions. Side effects - a negative moment with intramuscular, intravenous administration of the solution or taking pills, but a significant antiallergic effect often explains the use of the drug.

What is Diphenhydramine?

According to the accepted medical classification, diphenhydramine belongs to histamine receptor blockers and antiallergic drugs. The active ingredient of the composition is diphenhydramine hydrochloride, which acts on the central nervous system, inhibiting histamine and cholinergic structures with brain receptors. Due to this effect, a spasm of smooth muscles is relieved, and a person’s condition for allergies is relieved.

Composition and release form

The main forms of release of the drug are injection solution and tablets. The first can be taken orally or instilled into the eyes. In addition, rectal suppositories are produced based on the active ingredient. The composition, description of the drugs are listed in the table:

White flat-cylindrical with chamfer and risky

The concentration of diphenhydramine, mg

30, 50 or 100 per 1 pc / 20 for children

Purified water for injection

Stearic acid, potato starch, colloidal silicon dioxide, lactose

Ampoules of 1 ml, 10 pcs. in a pack with instructions for use

Blisters or strips of 6 or 10 pcs., Packs of one blister

Physical and chemical properties of Dimedrol

The drug belongs to the blockers of histamine receptors in the brain. Due to this, Diphenhydramine relieves smooth muscle spasm, reduces capillary permeability, reduces the intensity of allergic reactions. Actively working substance of the composition of the local anesthetic drug has antiemetic activity, sedative effect, hypnotic effect.

The drug causes local anesthesia, which is manifested in the short-term sensation of numbness of the oral mucosa, has an antispasmodic effect. Dimedrol shows great efficacy in bronchospasm caused by histamine liberators (morphine), and less in allergic type. The drug is ineffective against asthma, can be combined with bronchodilators (Theophylline, Ephedrine).

Diphenhydramine shows antagonism with the effect of histamine, increases blood pressure. In patients with circulating blood volume deficiency, parenteral administration of Dimedrol may cause a decrease in pressure and increase hypotension due to ganglioblokiruyuschego action. With local brain damage and epilepsy, the drug can activate epileptic discharges and provoke an attack of epilepsy.

The drug begins to act in a few minutes, its effect lasts up to 12 hours. Diphenhydramine binds to plasma proteins by 98%, is metabolized in the liver, lungs and kidneys, excreted by the kidneys, with breast milk in the form of metabolites conjugates with glucuronic acid. The active substance of the composition penetrates the blood-brain barrier, the trace amount is found in breast milk.

Dosing and Administration

Depending on the form of release Dimedrol different method of its use and dosing regimen. For example, tablets are taken orally, have a child and adult dosage, the course of administration depends on the type of disease and the severity of its course. The solution has a wider range of applications - it is administered intramuscularly, intravenously, used in the form of drops and orally.

Standard dosages for children

Inside the drug can be used in the form of a solution for injection (just from the ampoule).

  • Children up to 1 year at a dose of 2-5 mg
  • from 2 to 5 years - from 5 to 15 mg,
  • from 16 to 12 years old - from 15 to 30 mg at a time.

It is best to give Diphenhydramine with allergies to the child in the form of rectal suppositories - candles. First you need to make a child microclysters, and then enter the candle with the content of diphenhydramine:

  • 5 mg (for children under 3 years),
  • 10 mg (from 3 to 4 years),
  • 15 mg (from 5 to 7 years),
  • 20 mg (from 8 to 14 years).

Dosage for intramuscular and intravenous administration is not given, since It is impossible to administer the drug independently to the children, the dose is discussed with the doctor.

Regarding the duration of the reception, Dr. E.O. Komarovsky says: it makes no sense to take the drug for more than 6 days. If during this period diphenhydramine did not help, you need to change the drug.

Side effects

The most famous side effect of Diphenhydra is perhaps the drowsiness it causes. Other manifestations of its influence on the nervous system:

Photo: A negative feedback from a girl about Dimedrol, associated with its side effects.

  • general weakness
  • dullness of attention
  • headache,
  • dizziness,
  • discoordination
  • anxiety, irritability (in children),
  • confusion,
  • tremor,
  • visual impairment.

Among other side effects of the drug Dimedrol, the instructions for its use in allergy include the following:

  • lowering blood pressure
  • increase in heart rate,
  • dry mouth
  • numbness of the oral mucosa,
  • nausea,
  • vomiting
  • loose stools
  • violation of urination,
  • nasal congestion,
  • bronchial secretion thickening
  • difficulty breathing
  • allergic reactions.

When used together with the drug, as well as with long-term use in high doses, it can cause hallucinations, so sometimes it is used as a drug.

Among those who take diphenhydramine from allergies, reviews, mostly positive. Sedative and hypnotic effect is noted by almost everything, but the other side effects occur very rarely.

Allergy ointment with Dimedrol - recipe known

  • distilled water - 20 ml
  • 90% ethyl alcohol - 20 ml,
  • anesthesin - 1 cube,
  • Dimedrol - 5 ml,
  • white clay - 30g,
  • zinc oxide powder - 30g (can be replaced with baby powder).

Preparation: In a clean bowl, mix water and alcohol, dissolve 1 cube of anesthesin in the mixture. In the resulting solution, enter the clay, diphenhydramine and zinc oxide. Stir the mixture thoroughly.

I must say that the recipe for talkers for allergies with Dimedrol includes components that are not always possible to quickly find, so it is easier to buy a talker ointment at the pharmacy.

Diphenhydramine for allergies

Diphenhydramine for allergies

Diphenhydramine (diphenhydramine) is a domestic drug used in medicine for over 50 years. Diphenhydramine is most commonly used as it blocks the production of histamines in the patient’s body, preventing the development of allergic symptoms.

Despite the fact that this drug belongs to the first generation of anti-allergic drugs and has some side effects, it is still in demand in medical practice for allergies.

Its demand, first of all, is connected with availability in a price category. In 2012, according to the WHO recommendation, Dimedrol was again added to the list of essential medicines. Currently, the drug is most often used in inpatient treatment to relieve allergies. In addition, it can be actively used to relieve pain and high body temperature. In this case, the drug is combined with a 50% solution of analgin and 2% solution of papaverine hydrochloride.


With an incorrectly chosen dosage of the drug, diphenhydramine overdose may occur. It can be expressed in depression (agitation) of the central nervous system, facial flushing, dry mouth. With an overdose in childhood, convulsive syndrome may develop.

In this case, you must provide first aid to the victim:

  • it is important to induce artificial vomiting,
  • perform a gastric lavage,
  • the use of enterosorbents (activated carbon, enterosgel, lactofiltrum, polysorb, etc.) is recommended. These drugs actively remove harmful substances from the body.

After these activities, symptomatic therapy prescribed by the attending physician is recommended.

Side effects

The use of diphenhydramine for allergies can cause the following negative symptoms:

central nervous system

  • painful headache, weakness, dizziness,
  • confusion, inhibition, drowsiness,
  • over-stimulation, poor coordination of movements,
  • sometimes there are insomnia, neuritis, paresthesia,
  • euphoria, cramps, possibly anxiety.
  • bouts of nausea, accompanied by a gag reflex,
  • may experience loose stools or constipation, anorexia,
  • pain in the stomach, increased dryness of the mucous membranes.
  • a sharp drop in blood pressure, tachycardia, extrasystoles.
  • possible deterioration of vision
  • acute labyrinthitis, diplopia, hearing impairment.
  • development of anaphylaxis,
  • urticaria, photosensitivity.

From the side of blood formation organs

  • there may be urinary retention,
  • marked failures of the menstrual cycle.

In addition, the drug can cause a feeling of fever and excessive sweating.

Similar drugs for pharmacological properties are suprastin, pipolfen, tavegil. These drugs have a similar effect, but differ from Dimedrol less adverse manifestations.

More modern antihistamines include Erius, Zyrtec, Claritin, Cetrin, Loratadine. They are more easily tolerated, do not have a hypnotic effect, act longer.

Diphenhydramine copes well with allergic manifestations. Among all the drugs intended for the treatment of the disease, it has a low cost. However, despite the affordability, many patients suffer from numerous side effects associated with taking the drug.

Especially unpleasant is the constant drowsiness and lethargy accompanying patients throughout the treatment. Therefore, allergy sufferers are forced to spend most of their time in the hospital or at home. They complain of dizziness and weakness.

Many parents prefer, when allergies occur in children, preparations of the latest generations, the side effects of which are minimal. Moreover, most pediatricians prohibit the use of Dimedrol in childhood.

However, there are such situations when Dimedrol is simply necessary. At high temperatures, which cannot be removed by other drugs, a lytic mixture with the addition of dimedrol solution is used.

In conclusion, it should be noted that all drugs should be taken only after prior consultation with your doctor. Only a qualified allergist can identify the true cause of allergies and prescribe adequate treatment.

General information about the drug

Often, this drug is prescribed during inpatient treatment to relieve seizures. In addition, it is often used in the "trinity":

These drugs are mixed in a syringe and injected against high fever and pain in infectious diseases.

There are several forms of release of the above drug:

  • tablet,
  • powder,
  • candles (for the smallest),
  • for external use - gel, cream, ointment.

Tablets are rarely used because of the high probability of side effects and a wide range of contraindications. Diphenhydramine is most often administered intramuscularly. How can he help allergies?

Operating principle

The main effects of the drug:

The drug reduces the permeability of blood vessels, blocks the activity of histamine receptors, thereby preventing the development of an allergic attack.

In addition, it eliminates puffiness, visibly alleviates itching, has an antispasmodic effect and serves as a local anesthetic. After administration of the drug inside its maximum effectiveness occurs in an hour or three.

The duration of exposure to the body is equivalent to four to six hours.

Now you know what Dimedrol helps a person with hypersensitivity. By the way, this medication can treat allergic attacks not only in adults, but also in a child. What about its use during pregnancy?

Is it possible or not medicine is pregnant?

In such a crucial period in the life of a woman, the above medication is not taken. In addition, it is contraindicated nursing moms. In a newborn, a drug can develop pathologies of a different nature and provoke complications of congenital diseases.

Safe analogues are antihistamine generations 3:

The only drawback of the above analogs is the higher price.

How is the medicine applied?

Adults are recommended to take the injection three times (if the reaction is severe) per day at a dosage of 30-50 mg. The duration of treatment is equivalent to ten to fifteen days.

Children between two and six years old are prescribed a maximum daily dosage of 75 mg, children ages 6-12 years old - 150 mg maximum per day. The ointment with diphenhydramine is applied several times a day to areas of the body affected by rashes or peeling.

Sometimes the above medication is used to treat allergic attacks in animals, in particular in dogs. The amount of medication for a single injection is selected individually, taking into account the weight of the pet.

In no case is it recommended to prick the medicine to the pet on its own without prior consultation with the veterinarian.

Are there any contraindications / side effects?

Above in the article it was already mentioned that this drug has some prohibitions to receive and side effects. Reception is prohibited to people with:

  • individual intolerance,
  • pregnant and lactating moms,
  • gastric and duodenal ulcer,
  • angle-closure glaucoma,
  • under two years old
  • alcoholics (medication with alcohol is categorically incompatible).

Side effects of the drug are manifested mainly after exceeding the permissible dosage. These include:

  • difficulty breathing
  • violations of a different nature in the central nervous system,
  • dry mouth and redness of the face,
  • seizures (develop mainly in children).

Knowing the risks, think again whether to use diphenhydramine for non-serious episodes of hypersensitivity. For the prevention of attacks, it is better to give preference to light antihistamines.

The high cost of drugs such as Zyrtec, Loratadin, Erius, etc., due to the absence of serious contraindications and side effects.

The effectiveness of the drug is confirmed by the positive reviews of allergies, which I suggest you familiarize yourself with.

This medicine helped me quickly cure a serious reaction to pollen. The only thing that did not please was the feeling of sleepiness, which haunted me constantly during the treatment.

Pricked the drug to the child with a strong allergic attack. After the first injection, most of the symptoms disappeared. Then they were treated with Diazolin, because they did not want to risk it.

In general, I can’t say anything bad about Dimedrol. The only thing that can be alerted is contraindications, since there are too many of them.

Once this shot saved my life. Not knowing, I ate a piece of red fish, to which I have a terrible allergy. Soon there was a seizure in the form of suffocation and shock.

In the restaurant where all this happened, fortunately, there was a medic. He sent a waiter for Dimedrol to the pharmacy. If it were not for this medicine, everything could have ended in failure.

That's all the information about the anti-allergic properties of Dimedrol. If you liked the article, tell your friends about it on social networks, and subscribe to updates of this site. Good luck to you!

Article author: Elena Smirnova (dermatologist)

General information about the drug

Diphenhydramine is available in several dosage forms:

  1. Tablets - a form round flat-cylindrical, white shade, there is a facet.
  2. Intravenous and intramuscular solution - liquid without color, in ampoules.

The active substance in tablets is hydrochloride diphenhydramine (50 mg per tablet). In solution, the content of diphenhydramine is 10 mg per 1 ml.

In addition, auxiliary components are included in the drug. For tablets, this is:

  • water soluble methylcellulose,
  • lactose monohydrate,
  • colloidal silicon dioxide,
  • corn starch,
  • stearic acid.

For the solution, an additional component is water for injection.

Impact on the body

Diphenhydramine tablets and injections can block histamine receptors, eliminating histamine effects. It can reduce or prevent spasms of smooth muscle mass, increase capillary permeability, eliminate puffiness and itching.

The medicine taken inside is quickly and efficiently absorbed by binding to plasma protein by almost 100 percent. The maximum content in the plasma occurs after 4 hours from the moment of oral administration. A significant amount of the drug is metabolized in the liver cells. Spread throughout the body is wide, up to the passage of the placenta and the blood-brain barrier.

The withdrawal from the body is one day. The maximum effectiveness of the effect of the drug occurs within an hour after administration and lasts from 4 to 6 hours.

Who is appointed and what contraindications exist

Indications for taking Dimedrol from allergies are as follows:

Taking this drug is not recommended in the following cases:

  1. If the patient suffers from a strong sensitivity to certain components.
  2. A patient has been diagnosed with closed-type glaucoma, prostatic hyperplasia, gastric or duodenal ulcer, bladder neck stenosis, bronchial asthma, epilepsy.
  3. No pills are prescribed if the age category of the patient is under seven years old.

Pregnant women and nursing mothers in the treatment of this drug is recommended to be very careful and be regularly monitored by a doctor.

Symptoms of overdose and side effects

When deviations from the prescribed doses of the drug may appear certain symptoms:

  • depression of the central nervous system
  • excitement or depression (typical for children),
  • pupil expansion,
  • feeling of dryness in the mouth.

There is no special antidote in such situations. In cases of overdosing, it is necessary to perform a gastric lavage, if there is a need - to conduct symptomatic treatment in the form of medication to increase the pressure in the arteries, intravenous administration of fluids replacing the plasma, oxygen pillow. Analeptic and epinephrine are strictly prohibited. Read more about the overdose of this drug can be found here.

As a manifestation of side effects, many note a state of drowsiness, dry mouth, dizziness, numbness of the oral mucosa, nausea, tremor, headaches, general weakness, a decrease in mental health, deviations in coordination of movements.

In childhood insomnia may develop, irritability appears or euphoria is felt.

Application features

People involved in activities involving increased attention and a quick mental reaction, you must be extremely careful when taking Diphenol. During the period of therapy it is best not to be in the sunlight, not to drink alcohol.

When visiting the hospital, it is imperative to warn the doctor about taking this drug formulation. The fact is that antiemetic actions can make it difficult to diagnose appendicitis or identify signs of overdose of other medicines.

Children under seven years old are best to give pills whose weight is 30 mg. At the same time, they should be divided by the number of visits per day set by the doctor.

For babies who are not yet a year old, you need to order cooked powders from pharmacies.

Monoamine oxidase inhibitors can enhance anticholinergic activation of diphenhydramine. If a psychostimulant is prescribed with Dimedrol, then antagonistic interaction is possible.

This medicine can reduce the effectiveness of apomorphine, which is used as an emetic during the treatment of poisoning.

Opinion of patients and doctors

Reviews of specialists and patients confirm the effectiveness of Dimedrol in the fight against allergies. The drug quickly eliminates allergenic signs, relieves the condition, creates a long-lasting effect.

But at the same time there is an important feature - it is necessary to take it only as directed by the doctor, strictly observing the dosage. And it is necessary to take into account that in sleep it tends very much.

When my child was two years old, he behaved excitedly at night. The doctor prescribed diphenhydramine. My grandmother and I gave him a quarter pill for the night, but the effect was completely unexpected. The son did not fall asleep at all, told me that bunnies run around the walls. Probably, the dose was still high.

For a long time I suffer from allergies, I have tried a huge amount of drugs. From time to time the doctor prescribes diphenhydramine. Recently, he did not drink, because there was no need for this. The medicine helps a lot, especially if I'm on a trip. True, after half an hour I want to sleep a lot. But the performance is beautiful - it saves from allergenic symptoms for three to four days. In a critical situation, it helps out great!

Svetlana, 45 years old

Recently prescribed diphenhydramine. A very powerful remedy, when compared with Aleron, literally in 30 minutes all the symptoms of allergy disappeared. But he began to dream at a dream - there was simply no strength to endure. I do not advise using this medicine in the workplace - it will fly in from the authorities!

The drug is serious, different sedative effects, the dose must be determined in each case individually. Even my children are allergic to citrus fruits, and only Dimedrol helps. I give the fourth part of the tablet, are redness and itching. In any treatment it is necessary to remember the main principle - not to harm.

How much is the conditions of sale and storage

Price Dimedrol pharmacy kiosks ranging from 27 Russian rubles, depending on the form of release. It is possible to buy medicine upon presenting a prescription issued by a doctor.

Tablets are best stored in a dry place, protected from sunlight. For a solution, the storage temperature should not exceed 30 degrees Celsius. The medicine must be protected from children.

The term of the drug - up to 5 years.

What can replace

The main analogues of Dimedrol that act like this drug are:

  1. Diphenhydra bufus - solution with anti-allergic activity, creating antispasmodic and moderate ganglioblokiruyuschee effects. Is taken orally, causes sedation and drowsiness, has antiemetic effects. When used outdoors, it helps well against allergenic manifestations.
  2. Dramina - available in pill form. After ingestion, the medicine is perfectly absorbed, being distributed among the tissues of the organs. It creates a sedative, antiemetic, anti-allergic effect, relieves from dizziness. From the body is excreted along with urine almost in full during the day.
  3. Kalmaben - tablets of a white shade. They create a sedative and hypnotic effect, significantly facilitate the process of falling asleep, increase the duration of sleep. The effect of the drug occurs 30 minutes after administration. Can be used for allergies.
  4. Dimedrol UVI - after ingestion, the drug causes sedative and hypnotic effects, creates a parietal effect (moderate), has a central anticholinergic activity. Absorbed from the gastrointestinal tract quickly enough.